Trail Blazers vs. Celtics Prediction: Boston Predicted to Win Wednesday's NBA Game [3/5/2025]

NBA action continues on Wednesday at 7:00PM ET as the Portland Trail Blazers look to defy the odds against the Boston Celtics at TD Garden.

Based on updated simulations and today’s injury news, Dimers' advanced NBA model (see Dimers Pro for full access) projects the Celtics as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Portland-Boston game 10,000 times," said Damien Souness from Dimers.

"With the latest updates and numerous other variables, we estimate the Celtics' chance of winning at 76%, with the Trail Blazers at 24%."

This prediction follows the latest NBA Injury Report, which suggests the Celtics lineup will feature players like Jaylen Brown, Payton Pritchard and Derrick White, while the Trail Blazers will rely on Anfernee Simons, Deni Avdija and Shaedon Sharpe.

For a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Trail Blazers vs. Celtics predictions page.

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Celtics vs. Trail Blazers Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NBA game between the Trail Blazers and Celtics 10,000 times as part of our NBA predictions coverage.

Our famous predictive model gives the Celtics a 76% chance of beating the Trail Blazers. Our predicted final score has the Celtics winning 116-108.

According to our model, the Trail Blazers (+9) have a 54% chance of covering the spread, while the 224.5-point over/under has a 51% chance of going over.

Pre-Game Probabilities

Last Updated: 12:08AM, Mar 6

Spread

Over / Under

Moneyline

Trail Blazers

Trail Blazers +9.0

54%

46%

-106

-108

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Celtics

Trail Blazers POR

-106

Trail Blazers +9.0

54%

46%

See Matchup

Celtics BOS

-108

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Trail Blazers vs. Celtics Odds

We have researched the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Our model's biggest edge in today's Trail Blazers vs. Celtics matchup is on the total.

Our expert predictions, matched against the best odds, reveal the best NBA picks for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Trail Blazers vs. Celtics Player Props

Betting on Trail Blazers vs. Celtics NBA prop bets? We have crunched the numbers to project how each team's leading players will perform at TD Garden.

Anfernee Simons is expected to lead the Trail Blazers with 19 points, 3 rebounds and 5 assists, while Jaylen Brown is projected to have 24 points, 6 rebounds and 5 assists for the Celtics.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Projected Box Scores for Every NBA Game

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Calling Our Shot's Free 🏀 Picks

Calling Our Shot produces daily NBA betting content, including the predictions featured below.

Blazers vs. Celtics Game-Day Updates and Essential Details

Wednesday's matchup between the Celtics and Trail Blazers at TD Garden is scheduled to commence at 7:00PM ET.

• Who: Portland Trail Blazers vs. Boston Celtics
• Date: Wednesday, March 5, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: TD Garden

Dimers.com's full preview of Wednesday's Trail Blazers vs. Celtics matchup includes our prediction, picks and the latest betting odds.

Before making any Portland vs. Boston picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Celtics, with a 76% win probability, will likely beat the Trail Blazers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Trail Blazers vs. Celtics insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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