Pirates vs. Marlins Prediction: Pittsburgh Predicted to Win MLB Opening Day Matchup [3/27/2025]

MLB Opening Day action continues on Thursday at 4:10PM ET as the Pittsburgh Pirates square off with the Miami Marlins at loanDepot park.

The Marlins will start Sandy Alcantara (0-0, 0.00 ERA), while the Pirates will counter with Paul Skenes (0-0, 0.00 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Pirates as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's Pittsburgh-Miami game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Pirates with a win probability of 58% and the Marlins with 42%."

For a closer look at Thursday's matchup, including best bets and picks, visit our interactive Pirates vs. Marlins predictions page.

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Pirates vs. Pirates Prediction: Who Will Win on MLB Opening Day?

Using trusted machine learning and data analysis, we have simulated the result of Thursday's MLB game between the Pirates and Marlins 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Pirates a 58% chance of beating the Marlins.

According to our model, the Marlins (+1.5) have a 58% chance of covering the run line, while the over/under total of 6.5 runs has an equal 50-50 chance of hitting.

Pre-Game Probabilities

Last Updated: 8:28PM, Mar 27

Moneyline

Over / Under

Run Line

Pirates

Win %

57%

43%

-146

+130

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See Matchup

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Marlins

Pirates PIT

-146

Win %

57%

43%

See Matchup

Marlins MIA

+130

Paul Skenes 0-0, 0.00 ERA

Sandy Alcantara 0-0, 0.00 ERA

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Pirates vs. Marlins Odds [3/27/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Marlins Picks and Best Bets

Our model's strongest edge in today's Pirates vs. Marlins matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Pirates vs. Marlins Game-Day Updates and Essential Details

Thursday's MLB game between the Marlins and Pirates at loanDepot park is scheduled to commence at 4:10PM ET.

• Who: Pittsburgh Pirates vs. Miami Marlins
• Date: Thursday, March 27, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: loanDepot park

Dimers.com's full preview of Thursday's Pirates vs. Marlins matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. Miami picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Pirates, with a 58% win probability, will likely beat the Marlins on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Marlins insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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