Pirates vs. Dodgers Prediction: Dodgers Predicted to Win Friday's MLB Matchup [4/25/2025]

The Los Angeles Dodgers and Pittsburgh Pirates will meet in MLB action at Dodger Stadium on Friday, starting at 10:10PM ET.

The Dodgers will start Yoshinobu Yamamoto (3-1, 0.93 ERA), pitting him against Paul Skenes (2-2, 2.87 ERA) for the Pirates.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Dodgers as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Pittsburgh-LA Dodgers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Dodgers' chance of winning is 63%, while the Pirates' is 37%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Pirates vs. Dodgers predictions page.

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Dodgers vs. Pirates Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the outcome of Friday's MLB matchup between the Pirates and Dodgers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Dodgers a 63% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 59% chance of covering the run line, while the 7-run over/under has a 53% chance of staying under.

Pre-Game Probabilities

Last Updated: 2:28AM, Apr 26

Moneyline

Over / Under

Run Line

Pirates

Win %

36%

64%

+190

-220

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Dodgers

Pirates PIT

+190

Win %

36%

64%

See Matchup

Dodgers LAD

-220

Paul Skenes 2-2, 2.87 ERA

Yoshinobu Yamamoto 3-1, 0.93 ERA

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Pirates vs. Dodgers Odds [4/25/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Pirates vs. Dodgers Picks and Best Bets

Our model's strongest edge in today's Pirates vs. Dodgers matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Pirates vs. Dodgers Game-Day Updates and Essential Details

Friday's MLB game between the Dodgers and Pirates at Dodger Stadium is scheduled to start at 10:10PM ET.

• Who: Pittsburgh Pirates vs. Los Angeles Dodgers
• Date: Friday, April 25, 2025
• Time: 10:10PM ET/7:10PM PT
• Venue: Dodger Stadium

Dimers.com's full preview of Friday's Pirates vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. LA Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Dodgers, with a 63% win probability, will likely beat the Pirates on Friday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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