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Pirates vs. Angels Prediction: Angels Predicted to Win Tuesday's MLB Matchup [4/22/2025]
Our expert prediction for Tuesday's Pittsburgh Pirates vs Los Angeles Angels matchup.

The Los Angeles Angels and Pittsburgh Pirates will meet in MLB action at Angel Stadium on Tuesday, starting at 9:38PM ET.
José Soriano (2-2, 3.16 ERA) will be the starting pitcher for the Angels, up against Bailey Falter (1-2, 4.91 ERA) for the Pirates.
Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Angels as the most likely winner of today's game.
"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Pittsburgh-LA Angels game," said Dimers' Chief Content Officer, Nick Slade.
"By incorporating recent updates and various factors, our prediction shows the Angels with a win probability of 64%, compared to 36% for the Pirates."
For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Pirates vs. Angels predictions page.
Angels vs. Pirates Prediction: Who Will Win, Cover the Run Line?
Using trusted machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB game between the Pirates and Angels 10,000 times as part of our MLB predictions coverage.
Our leading predictive model gives the Angels a 64% chance of beating the Pirates.
According to our model, the Pirates (+1.5) have a 54% chance of covering the run line, while the 8.5-run over/under has a 51% chance of staying under.
Pirates vs. Angels Odds [4/22/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
Bet Type | Pirates | Angels |
---|---|---|
Run Line | +1.5 (-130) | -1.5 (+116) |
Moneyline | +155 | -180 |
Total | o8.5 (-115) | u8.5 (+102) |
All odds are correct at the time of publication and are subject to change.
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Pirates vs. Angels Picks and Best Bets
Our model's strongest edge in today's Pirates vs. Angels matchup is on the run line.
Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free MLB Picks
Calling Our Shot produces daily MLB betting content, including the predictions featured below.
Pirates vs. Angels Game-Day Updates and Essential Details
Tuesday's MLB game between the Angels and Pirates at Angel Stadium is scheduled to begin at 9:38PM ET.
- Who: Pittsburgh Pirates vs. Los Angeles Angels
- Date: Tuesday, April 22, 2025
- Time: 9:38PM ET/6:38PM PT
- Venue: Angel Stadium
Dimers.com's in-depth preview of Tuesday's Pirates vs. Angels matchup includes our prediction, picks and the latest betting odds.
Before making any Pittsburgh vs. LA Angels picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Angels, with a 64% win probability, will likely beat the Pirates on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Angels insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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