Pirates vs. Reds Prediction: Cincinnati Predicted to Win Saturday's MLB Matchup [4/12/2025]

The Cincinnati Reds will take on the Pittsburgh Pirates in MLB action at Great American Ball Park on Saturday, beginning at 6:40PM ET.

Andrew Abbott (0-0, 0.00 ERA) will be on the bump for the Reds, while the Pirates are going with Andrew Heaney (0-0, 1.50 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Pittsburgh-Cincinnati game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Reds are more likely to win, while the Pirates have a lower chance of victory."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Pirates vs. Reds predictions page.

Pirates vs. Pirates Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the result of Saturday's MLB matchup between the Pirates and Reds 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Reds a 54% chance of beating the Pirates.

According to our model, the Pirates (+1.5) have a 64% chance of covering the run line, while the 8-run over/under has an equal 50-50 chance of hitting.

Pirates vs. Reds Odds [4/12/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Reds
Run Line	+1.5 (-198)	-1.5 (+165)
Moneyline	+106	-124
Total	o8 (-115)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Reds Picks and Best Bets

Our model's biggest edge in today's Pirates vs. Reds matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Pirates vs. Reds Game-Day Updates and Essential Details

Saturday's MLB action between the Reds and Pirates at Great American Ball Park is scheduled to commence at 6:40PM ET.

• Who: Pittsburgh Pirates vs. Cincinnati Reds
• Date: Saturday, April 12, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Great American Ball Park

Dimers.com's comprehensive preview of Saturday's Pirates vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Reds, with a 54% win probability, will likely beat the Pirates on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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