Pirates vs. Yankees Prediction and Odds - Sep 21, 2022

The New York Yankees square off with the Pittsburgh Pirates in MLB action at Yankee Stadium on Wednesday, commencing at 7:05PM ET.

Luis Severino (5-3, 3.45 ERA) will start for the Yankees, while the Pirates will counter with Roansy Contreras (5-4, 3.24 ERA).

Dimers' free betting picks for Pirates vs. Yankees, as well as game predictions and betting odds, are featured in this article.

Who will win Pirates vs. Yankees?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's Pirates-Yankees MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Yankees a 70% chance of defeating the Pirates.

More: Pirates vs. Yankees Simulated 10K Times

Pirates vs. Yankees Current Odds

• Run Line: Yankees -1.5 (-130), Pirates +1.5 (+114)
• Moneyline: Yankees -275, Pirates +240
• Total: Over/Under 7.5 (-115/+100)

Run Line, Moneyline and Over/Under

The Yankees are -1.5 favorites against the Pirates, with -130 at Caesars Sportsbook the best odds currently available.

For the underdog Pirates (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +114.

BetMGM currently has the best moneyline odds for the Yankees at -275. That means you can risk $275 to win $100, for a total payout of $375, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Pirates at +240, where you can put down $100 to profit $240, earning a total payout of $340, if they win.

The Over/Under is set at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Yankees (-1.5) are a 53% chance of covering the run line, while the 7.5-run Over/Under is a 53% chance of going Over.

More: Best Prop Bets Today

Best Bets for Pirates vs. Yankees

• Run Line: Pirates +1.5 @ +114 via FanDuel Sportsbook (0.8% edge)
• Moneyline: Pirates @ +240 via FanDuel Sportsbook (0.7% edge)
• Total: Over 7.5 @ -115 via Caesars Sportsbook (53% probability)

Our best bets are based on detailed modeling and betting expertise to help you make better investments with your state's legal sportsbooks.

Even though the Yankees are more likely to cover the run line, our best bet of Pirates +1.5 is based on the expectation of that happening, according to DimersBOT, and the best odds available.

And while the Yankees are more likely to win the game, according to DimersBOT, taking the Pirates moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers is crucial to being a profitable sports bettor in the long run.

Pirates vs. Yankees Prediction

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Dimers has full betting coverage of Wednesday's Pirates-Yankees matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so refresh this article for any changes to our betting insights ahead of Pirates vs. Yankees on Wednesday September 21, 2022.

Pirates vs. Yankees 2022 Game Info

Wednesday's matchup between the Yankees and Pirates at Yankee Stadium is scheduled to commence at 7:05PM ET.

• Who: Pittsburgh Pirates vs. New York Yankees
• Date: Wednesday September 21, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Yankee Stadium

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Want more MLB previews like this?

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That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find value in the markets. This allows us to create the most authoritative MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not see for yourself?

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.