Pirates vs. Reds Prediction for MLB Friday [9/22/2023]

The Cincinnati Reds and Pittsburgh Pirates are scheduled to meet in MLB action at Great American Ball Park on Friday, starting at 6:40PM ET.

Andrew Abbott (8-5, 3.68 ERA) will be the starting pitcher for the Reds, while the Pirates will counter with Andre Jackson (1-3, 5.40 ERA).

Dimers' top betting picks for Pirates vs. Reds, plus game predictions and best odds, are featured in this article.

Who Will Win: Pirates vs. Reds

Using state-of-the-art machine learning and data, Dimers.com has simulated Friday's Pirates-Reds MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Reds a 60% chance of winning against the Pirates.

More: Pirates vs. Reds Simulated 10K Times

Pirates vs. Reds Odds [9/22]

• Run Line: Reds -1.5 (+140), Pirates +1.5 (-148)
• Moneyline: Reds -150, Pirates +135
• Total: Over/Under 9.5 (-102/-110)

The Reds are listed as -1.5 favorites against the Pirates, with +140 at PointsBet the best odds currently available.

For the underdog Pirates (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -148.

PointsBet currently has the best moneyline odds for the Reds at -150, which means you can risk $150 to win $100, for a total payout of $250, if they get the W.

On the other hand, BetMGM currently has the best moneyline odds for the Pirates at +135, where you can bet $100 to profit $135, earning a total payout of $235, if they win.

The Over/Under for total runs scored sits at 9.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -102, while PointsBet currently has the best odds for the Under at -110.

As always, check out all the legal sportbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) have a 58% chance of covering the run line, while the Over/Under total of 9.5 runs has a 53% chance of going Under.

More: Free Prop Picks

Best Bets: Pirates vs. Reds

• Run Line: Reds -1.5 @ +140 via PointsBet (0.6% edge)
• Moneyline: Reds @ -150 via PointsBet (60% probability)
• Total: Under 9.5 @ -110 via PointsBet (53% probability)

Our best bets are based on complex modeling and betting intelligence to serve you the best possible plays 24/7.

Even though the Pirates are more likely to cover the run line, our best bet of Reds -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

Pirates vs. Reds Prediction

Dimers.com predicts that the Reds are more likely to beat the Pirates in the MLB game on Friday.

This prediction is based on detailed data-driven analysis, with the Reds boasting a 60% chance of winning after conducting 10,000 game simulations.

Click or tap on See Matchup to find out more.

Dimers has full coverage of Friday's Pirates-Reds game, including pregame predictions, best betting picks, and live updates.

Don't forget, DimersBOT updates often, so keep checking this article for any changes to our betting insights before Pirates vs. Reds on Friday September 22, 2023.

Pirates vs. Reds 2023

Friday's MLB game between the Reds and Pirates at Great American Ball Park is scheduled to begin at 6:40PM ET.

• Who: Pittsburgh Pirates vs. Cincinnati Reds
• Date: Friday September 22, 2023
• Time: 6:40PM ET / 3:40PM PT
• Venue: Great American Ball Park

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Make Smarter Sports Betting Decisions with Dimers

Dimers' predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Pirates vs. Reds picks can help you make informed decisions, it's important that you gamble responsibly and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the World Series, with our data-driven probabilities compared to the best odds on the market.