Phillies vs. Cubs Prediction and Odds - Sep 27, 2022

The Chicago Cubs take on the Philadelphia Phillies in MLB action at Wrigley Field on Tuesday, starting at 7:40PM ET.

Marcus Stroman (4-7, 3.80 ERA) will start for the Cubs, pitting him against Zack Wheeler (11-7, 2.98 ERA) for the Phillies.

Dimers' top betting picks for Phillies vs. Cubs, as well as game predictions and best odds, are detailed in this article.

Who will win Phillies vs. Cubs?

Using state-of-the-art computer power and data, Dimers.com has simulated Tuesday's Phillies-Cubs MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Phillies a 60% chance of getting the W against the Cubs.

More: Full Betting Analysis for Phillies vs. Cubs

Phillies vs. Cubs Odds

• Run Line: Cubs +1.5 (-120), Phillies -1.5 (+105)
• Moneyline: Cubs +146, Phillies -165
• Total: Over/Under 6.5 (-120/+105)

Run Line, Moneyline and Over/Under

The Cubs are +1.5 underdogs against the Phillies, with -120 at DraftKings Sportsbook the best odds currently available.

For the favored Phillies (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +105.

FanDuel Sportsbook currently has the best moneyline odds for the Cubs at +146. That means you can throw down $100 to profit $146, earning a total payout of $246, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Phillies at -165, where you can risk $165 to win $100, for a total payout of $265, if they come out on top.

The Over/Under for total runs scored is set at 6.5 with Caesars Sportsbook, which currently has the best odds for the Over at -120, while BetMGM currently has the best odds for the Under at +105.

As always, check out all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 54% chance of covering the run line, while the 6.5-run Over/Under is a 60% chance of going Over.

More: Free Prop Picks

Best Bets for Phillies vs. Cubs

• Run Line: Cubs +1.5 @ -120 via DraftKings Sportsbook (54% probability)
• Moneyline: Cubs @ +146 via FanDuel Sportsbook
• Total: Over 6.5 @ -120 via Caesars Sportsbook (60% probability) 🔥

When you see a 🔥, that means you've found one of Dimers' best free picks today across all major pro and college sports.

Our best bets are based on detailed modeling and wagering expertise to serve you the best possible plays every time.

While the Phillies are more likely to win the game, according to DimersBOT, betting on the Cubs moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers is pivotal to achieving long-term profitability as a bettor.

Phillies vs. Cubs Probabilities

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Dimers has full betting coverage of Tuesday's Phillies-Cubs matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so refresh this article for any changes to our betting analysis before Phillies vs. Cubs on Tuesday September 27, 2022.

Phillies vs. Cubs 2022 Game Info

Tuesday's action between the Cubs and Phillies at Wrigley Field is scheduled to begin at 7:40PM ET.

• Who: Philadelphia Phillies vs. Chicago Cubs
• Date: Tuesday September 27, 2022
• Time: 7:40PM ET / 4:40PM PT
• Venue: Wrigley Field

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What other MLB games are on today?

Now you've got the 411 on Phillies vs. Cubs, check out the latest betting predictions for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.