Phillies vs. Cubs Prediction: Close Contest Projected After New Data Released for Saturday's MLB Matchup [4/26/2025]

The Chicago Cubs will take on the Philadelphia Phillies, in what is expected to be a tight MLB game, at Wrigley Field on Saturday, starting at 4:05PM ET.

Ben Brown (2-1, 4.57 ERA) will be on the bump for the Cubs, while the Phillies have opted for Jesús Luzardo (2-0, 2.08 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts an equal chance for both the Cubs and Phillies to win today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Philadelphia-CHI Cubs game," said Dimers' Chief Content Officer, Nick Slade.

"Based on the latest updates and extensive data, we predict a 50-50 chance for both the Cubs and Phillies, making it a highly competitive matchup."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Phillies vs. Cubs predictions page.

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Cubs vs. Phillies Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Saturday's MLB matchup between the Phillies and Cubs 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently can't split the two teams, giving both the Phillies and Cubs a 50% chance of winning the game.

According to our model, the Cubs (+1.5) have a 64% chance of covering the run line, while the 7-run over/under has an equal 50-50 chance of hitting.

Pre-Game Probabilities

Last Updated: 8:28PM, Apr 26

Moneyline

Over / Under

Run Line

Phillies

Win %

50%

50%

-114

-102

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See Matchup

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Cubs

Phillies PHI

-114

Win %

50%

50%

See Matchup

Cubs CHC

-102

Jesús Luzardo 2-0, 2.08 ERA

Ben Brown 2-1, 4.57 ERA

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Phillies vs. Cubs Odds [4/26/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Cubs Picks and Best Bets

Our model's biggest edge in today's Phillies vs. Cubs matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Phillies vs. Cubs Game-Day Updates and Essential Details

Saturday's MLB game between the Cubs and Phillies at Wrigley Field is scheduled to commence at 4:05PM ET.

• Who: Philadelphia Phillies vs. Chicago Cubs
• Date: Saturday, April 26, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: Wrigley Field

Dimers.com's comprehensive preview of Saturday's Phillies vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Philadelphia vs. CHI Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict a close game between the Phillies and Cubs on Saturday, with each team having a 50% chance of winning.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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