Penn State vs. Michigan State CFB Predictions and Odds - Nov 27, 2021

Michigan State hosts Penn State in College Football Week 13 action at Spartan Stadium on Saturday, beginning at 3:30 PM EST.

Dimers' free betting picks for Penn State vs. Michigan State, as well as game predictions and best odds, are detailed below.

Who will win Penn State vs. Michigan State?

Using advanced machine learning and data, Dimers.com has simulated Saturday's Penn State-Michigan State NCAA Football game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives Penn State a 60% chance of winning against Michigan State.

MORE: Penn State vs. Michigan State Simulated 10,000 Times

Penn State vs. Michigan State Point Spread, Moneyline and Over/Under

Michigan State is listed as the +3.5 underdog at home to Penn State, with -105 at FanDuel Sportsbook the best odds available.

For the favored Penn State (-3.5) to cover the spread, FanDuel Sportsbook also has the best odds on offer at -115.

DraftKings Sportsbook has the best moneyline odds for Michigan State at +180. That means you can bet $100 to profit $180, earning a total payout of $280, if it wins.

Meanwhile, PointsBet has the best moneyline odds for Penn State at -185, where you can risk $185 to win $100, for a total payout of $285, if it comes out on top.

The Over/Under sits at 51.5 with FanDuel Sportsbook, which has the best odds for the Over at -105, while PointsBet has the best odds for the Under at -110.

As always, check out all the sportsbooks that are available in your state for the best College Football odds and lines.

According to DimersBOT, Michigan State (+3.5) is a 51% chance of covering the spread, while the Over/Under total of 51.5 points is a 53% chance of going Under.

MORE: Today's Best Bets for All Major College Sports

Best Bets for Penn State vs. Michigan State

• Spread: Michigan State +3.5 at -105 with FanDuel Sportsbook (51% probability)
• Moneyline: Michigan State Win at +180 with DraftKings Sportsbook (4.3% edge) 🔥
• Over/Under: Under 51.5 at -110 with PointsBet (53% probability)

Any time you see a 🔥, you know it's one of Dimers' best free picks today across any sport.

While Penn State is more likely to win the game, according to DimersBOT, betting on Michigan State moneyline is the best option because of the 4.3% edge identified when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges seen on Dimers.com is crucial to being profitable in the long run.

Penn State vs. Michigan State Score Prediction

Dimers.com's predicted final score for Penn State vs. Michigan State at Spartan Stadium on Saturday has Penn State prevailing 27-24.

Use our interactive widget below to explore the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Penn State-Michigan State matchup, including pre-game predictions, best betting picks, and live updates.

Remember, DimersBOT updates often, so refresh this article for any changes to our betting insights ahead of Penn State vs. Michigan State on Saturday November 27, 2021.

Penn State vs. Michigan State 2021 CFB Game Info

When does Michigan State play Penn State in College Football?

• Date: Saturday November 27, 2021
• Time: 3:30 PM EST / 12:30 PM PST
• Venue: Spartan Stadium

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