Patriots vs. Colts Predictions and Odds - Dec 18, 2021

The Indianapolis Colts and New England Patriots lock horns in Week 15 of the NFL season at Lucas Oil Stadium on Saturday, starting at 8:15 PM EST.

Dimers' free betting picks for Patriots vs. Colts, plus our score prediction, best odds and player props, are featured in this article.

Who will win Patriots vs. Colts?

Based on cutting-edge computer power and data, Dimers.com has simulated Saturday's Patriots-Colts NFL game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Colts a 58% chance of getting the W against the Patriots.

MORE: Free Betting Analysis for Patriots vs. Colts

Point Spread, Moneyline and Over/Under

The Colts are listed as -1 favorites versus the Patriots, with -110 at Caesars Sportsbook the best odds available.

For the underdog Patriots (+1) to cover the spread, Caesars Sportsbook also has the best odds on offer at -110.

FanDuel Sportsbook has the best moneyline odds for the Colts at -118, which means you can risk $118 to win $100, for a total payout of $218, if they get the W.

Elsewhere, BetMGM has the best moneyline odds for the Patriots at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.

The Over/Under for total points scored is set at 46.5 with BetMGM, which has the best odds for the Over at -110, while DraftKings Sportsbook has the best odds for the Under at -105.

As always, make sure you check all the sportsbooks that are available in your state for the best NFL odds and lines.

According to DimersBOT, the Colts (-1) are a 53% chance of covering the spread, while the 46.5-point Over/Under is a 52% chance of going Under.

MORE: Super Bowl LVI Probabilities and Odds

Best Bets for Patriots vs. Colts

• Spread: Colts -1 at -110 with Caesars Sportsbook (53% probability)
• Moneyline: Colts Win at -118 with FanDuel Sportsbook (58% probability)
• Over/Under: Under 46.5 at -105 with DraftKings Sportsbook (52% probability)

Patriots vs. Colts Score Prediction

Dimers.com's predicted final score for New England vs. Indianapolis at Lucas Oil Stadium on Saturday has the Colts winning 23-21.

Use our interactive widget below to view the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Patriots-Colts matchup, including pre-game predictions, computer picks, and live win probabilities.

Patriots vs. Colts Player Props

Who will score the first touchdown in Patriots vs. Colts? The data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Patriots and Colts, as well as projected player stats.

And you know what, we provide this information to you for FREE to help you discover the best prop bets for Saturday's game.

According to DimersBOT, Indianapolis' Jonathan Taylor is most likely to score the first TD in Patriots vs. Colts.

DimersBOT gives Taylor a 19.0% chance of getting in for six first at Lucas Oil Stadium, while the Colts RB is a 63.0% chance of reaching the end zone at any point in the game.

First Touchdown Scorer Probabilities

New England Patriots

• Rhamondre Stevenson: 9.9% probability
• Jonnu Smith: 8.1% probability
• Nelson Agholor: 5.3% probability
• Brandon Bolden: 5.0% probability
• Jakobi Meyers: 4.9% probability

Indianapolis Colts

• Jonathan Taylor: 19.0% probability
• Michael Pittman: 7.6% probability
• Zach Pascal: 4.7% probability
• T.Y. Hilton: 4.5% probability
• Nyheim Hines: 3.8% probability

Anytime Touchdown Scorer Probabilities

New England Patriots

• Rhamondre Stevenson: 41.3% probability
• Jonnu Smith: 36.8% probability
• Nelson Agholor: 24.7% probability
• Jakobi Meyers: 24.0% probability
• Brandon Bolden: 23.0% probability

Indianapolis Colts

• Jonathan Taylor: 63.0% probability
• Michael Pittman: 35.2% probability
• Zach Pascal: 22.1% probability
• T.Y. Hilton: 21.1% probability
• Nyheim Hines: 18.2% probability

Projected Box Score

Of the starting quarterbacks, the Patriots' Mac Jones is projected for 238 passing yards and 1.5 passing touchdowns. The Colts' Carson Wentz is expected to throw for 231 yards and 1.3 TDs.

Patriots Starting QB

• Mac Jones: 238 Passing Yards, 1.5 Passing TDs

Colts Starting QB

• Carson Wentz: 231 Passing Yards, 1.3 Passing TDs

Patriots Rushing

• Rhamondre Stevenson: 73 Rushing Yards, 0.4 TDs
• J.J. Taylor: 19 Rushing Yards, 0.1 TDs
• Brandon Bolden: 16 Rushing Yards, 0.1 TDs

Colts Rushing

• Jonathan Taylor: 97 Rushing Yards, 0.8 TDs
• Carson Wentz: 17 Rushing Yards, 0.2 TDs
• Nyheim Hines: 11 Rushing Yards, 0.1 TDs

Patriots Receiving

• Nelson Agholor: 46 Receiving Yards, 0.2 TDs
• Jakobi Meyers: 42 Receiving Yards, 0.2 TDs
• Hunter Henry: 32 Receiving Yards, 0.2 TDs
• Kendrick Bourne: 30 Receiving Yards, 0.1 TDs
• Jonnu Smith: 27 Receiving Yards, 0.2 TDs

Colts Receiving

• Michael Pittman: 63 Receiving Yards, 0.3 TDs
• T.Y. Hilton: 37 Receiving Yards, 0.2 TDs
• Zach Pascal: 33 Receiving Yards, 0.2 TDs
• Nyheim Hines: 22 Receiving Yards, 0.1 TDs
• Jonathan Taylor: 21 Receiving Yards, 0.1 TDs

Don't forget, DimersBOT updates often, so keep checking this article for any changes to our betting analysis ahead of Patriots vs. Colts on Saturday December 18, 2021.

Bet $10, Win $200 if Patriots or Colts Score a TD

BetMGM, the king of sportsbooks, is offering new users the chance to Bet $10, Win $200 if the Patriots or Colts score a touchdown on Saturday.

That's right – bet 10 bucks and get 200 bucks in Free Bets if either team goes in for six. It's that simple.

To take advantage of this promo, join BetMGM via this exclusive link, deposit $10+ and place, as your first real-money bet after opening your account, a single $10 pre-game, moneyline wager on New England vs. Indianapolis.

If either team scores a TD, you'll receive $200 in Free Bets from BetMGM. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a partnership with (such as an online sportsbook), we may earn a referral fee.

Patriots vs. Colts 2021 Game Info

When do the Colts play the Patriots?

• Date: Saturday December 18, 2021
• Time: 8:15 PM EST / 5:15 PM PST
• Venue: Lucas Oil Stadium

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