Padres vs. Phillies Prediction - Oct 21, 2022

The Philadelphia Phillies take on the San Diego Padres in Game of the League Series at Citizens Bank Park on Friday, beginning at 7:37PM ET.

The Phillies will send Ranger Suárez (0-0, 2.70 ERA) to the mound, while the Padres will counter with Joe Musgrove (1-0, 1.38 ERA).

Dimers' top betting picks for Padres vs. Phillies, plus game predictions and best odds, are featured in this article.

Who will win Padres vs. Phillies?

Using state-of-the-art computer power and data, Dimers.com has simulated Friday's Padres-Phillies MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, can't split the two teams, giving both the Padres and Phillies a 50% chance of winning the game.

More: Padres vs. Phillies Simulated 10K Times

Padres vs. Phillies Odds

• Run Line: Phillies +1.5 (-165), Padres -1.5 (+145)
• Moneyline: Phillies +106, Padres -120
• Total: Over/Under 7.5 (+110/-115)

Run Line, Moneyline and Over/Under

The Phillies are currently +1.5 underdogs against the Padres, with -165 at DraftKings Sportsbook the best odds currently available.

For the favored Padres (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +145.

FanDuel Sportsbook currently has the best moneyline odds for the Phillies at +106, which means you can bet $100 to profit $106, earning a total payout of $206, if they win.

Elsewhere, BetMGM currently has the best moneyline odds for the Padres at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at +110, while BetMGM currently has the best odds for the Under at -115.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Phillies (+1.5) are a 64% chance of covering the run line, while the 7.5-run Over/Under is a 52% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Padres vs. Phillies

• Run Line: Phillies +1.5 @ -165 via DraftKings Sportsbook (64% probability)
• Moneyline: Phillies @ +106 via FanDuel Sportsbook (50% probability)
• Total: Over 7.5 @ +110 via Caesars Sportsbook (52% probability) 🔥

If you see a 🔥, you know you've found one of Dimers' best bets of the day across all sports.

Our best bets are based on complex simulations and wagering expertise to bring you the best possible plays 24/7.

Padres vs. Phillies Prediction

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Dimers has full betting coverage of Friday's Padres-Phillies matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for the latest betting analysis before Padres vs. Phillies on Friday October 21, 2022.

Padres vs. Phillies 2022 Game Info

Friday's game between the Phillies and Padres at Citizens Bank Park is scheduled to start at 7:37PM ET.

• Who: San Diego Padres vs. Philadelphia Phillies
• Date: Friday October 21, 2022
• Time: 7:37PM ET / 4:37PM PT
• Venue: Citizens Bank Park

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