Padres vs. Giants Prediction for MLB Wednesday [6/21/2023]

The San Francisco Giants take on the San Diego Padres in MLB action at Oracle Park on Wednesday, beginning at 9:45PM ET.

Ryan Walker (2-0, 1.65 ERA) will get the ball for the Giants, up against Yu Darvish (5-5, 4.74 ERA) for the Padres.

Dimers' free betting picks for Padres vs. Giants, plus game predictions and best odds, are featured below.

Who Will Win: Padres vs. Giants

Based on cutting-edge computer power and data, Dimers.com has simulated Wednesday's Padres-Giants MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Padres a 52% chance of getting the W against the Giants.

More: Padres vs. Giants Simulated 10,000 Times

Padres vs. Giants Odds [6/21]

• Run Line: Giants +1.5 (-165), Padres -1.5 (+150)
• Moneyline: Giants +105, Padres -115
• Total: Over/Under 7.5 (-115/+100)

The Giants are listed as +1.5 underdogs versus the Padres, with -165 at DraftKings Sportsbook the best odds currently available.

For the favored Padres (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +150.

PointsBet currently has the best moneyline odds for the Giants at +105. That means you can bet $100 to profit $105, earning a total payout of $205, if they win.

Elsewhere, BetMGM currently has the best moneyline odds for the Padres at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under is set at 7.5 with BetMGM, which currently has the best odds for the Over at -115, while FanDuel Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check all of the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Giants (+1.5) have a 61% chance of covering the run line, while the 7.5-run Over/Under has a 54% chance of going Over.

More: Live Scores for All Major Sports

Best Bets: Padres vs. Giants

• Run Line: Giants +1.5 @ -165 via DraftKings Sportsbook (61% probability)
• Moneyline: Giants @ +105 via PointsBet
• Total: Over 7.5 @ -115 via BetMGM (54% probability)

Our best bets are based on world-class simulations and wagering intelligence to help you make more informed decisions with your state's legal sportsbooks.

While the Padres are more likely to win the game, according to DimersBOT, betting on the Giants moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is one of the keys to achieving long-term profitability.

Padres vs. Giants Prediction

Dimers.com predicts that the Padres are more likely to defeat the Giants at Oracle Park on Wednesday.

This prediction is backed by comprehensive data-driven analysis, with the Padres having a 52% probability of winning after conducting 10,000 simulations of the game.

Click or tap on See Matchup to find out more.

Dimers has full coverage of Wednesday's Padres-Giants game, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep an eye on this page for any changes to our betting analysis ahead of Padres vs. Giants on Wednesday June 21, 2023.

Padres vs. Giants 2023

Wednesday's MLB matchup between the Giants and Padres at Oracle Park is scheduled to begin at 9:45PM ET.

• Who: San Diego Padres vs. San Francisco Giants
• Date: Wednesday June 21, 2023
• Time: 9:45PM ET / 6:45PM PT
• Venue: Oracle Park

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Our picks and predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Padres vs. Giants predictions can help you make informed decisions, it's crucial that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What Other MLB Games Are on Today?

Now you've got the 411 on Padres vs. Giants, take a look at the best analysis for all upcoming MLB games via our MLB picks and predictions. There you can find probabilities and odds, plus our best bets for each and every MLB matchup. Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good!

In addition to our leading MLB predictions, Dimers also offers the best MLB prop bets today, projecting home runs, RBIs, and more against the best odds available every single day of the MLB season.

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the World Series, with our data-driven probabilities paired with the best odds available.