Padres vs. Diamondbacks Prediction and Odds - Apr 21, 2023

The Arizona Diamondbacks square off with the San Diego Padres in MLB action at Chase Field on Friday, beginning at 9:40PM ET.

The Diamondbacks will have Zac Gallen (2-1, 3.33 ERA) start, while the Padres will counter with Seth Lugo (2-0, 2.70 ERA).

Dimers' best betting picks for Padres vs. Diamondbacks, plus game predictions and best odds, are featured in this article.

Who will win Padres vs. Diamondbacks?

Based on advanced computer power and data, Dimers.com has simulated Friday's Padres-Diamondbacks MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Diamondbacks a 53% chance of beating the Padres.

More: Full Betting Guide for Padres vs. Diamondbacks

Padres vs. Diamondbacks Game Odds

• Run Line: Diamondbacks +1.5 (-165), Padres -1.5 (+146)
• Moneyline: Diamondbacks -105, Padres -108
• Total: Over/Under 9.5 (+100/-114)

Run Line, Moneyline and Over/Under

The Diamondbacks are currently +1.5 underdogs against the Padres, with -165 at BetMGM the best odds currently available.

For the favored Padres (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +146.

In a sign of how close this game is expected to be, both the Diamondbacks and Padres are currently at minus-money betting odds to win on Friday.

PointsBet currently has the best moneyline odds for the Diamondbacks at -105. That means you can risk $105 to win $100, for a total payout of $205, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Padres at -108, where you can risk $108 to win $100, for a total payout of $208, if they come out on top.

The Over/Under sits at 9.5 with BetMGM, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -114.

As always, make sure you check all of the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Diamondbacks (+1.5) are a 64% chance of covering the run line, while the Over/Under total of 9.5 runs is a 54% chance of going Under.

More: Best Prop Bets to Make Today

Best Bets for Padres vs. Diamondbacks

• Run Line: Diamondbacks +1.5 @ -165 via BetMGM (64% probability)
• Moneyline: Diamondbacks @ -105 via PointsBet (53% probability)
• Total: Under 9.5 @ -114 via FanDuel Sportsbook (54% probability)

Our best bets are based on complex simulations and betting expertise to bring you the best possible plays 24/7.

Padres vs. Diamondbacks Betting Guide

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Dimers has full betting coverage of Friday's Padres-Diamondbacks matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this page for the latest betting analysis ahead of Padres vs. Diamondbacks on Friday April 21, 2023.

Padres vs. Diamondbacks 2023 Game Info

Friday's game between the Diamondbacks and Padres at Chase Field is scheduled to start at 9:40PM ET.

• Who: San Diego Padres vs. Arizona Diamondbacks
• Date: Friday April 21, 2023
• Time: 9:40PM ET / 6:40PM PT
• Venue: Chase Field

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What MLB games are on today?

Now you've got the 411 on Padres vs. Diamondbacks, take a look at the latest betting predictions for all upcoming MLB games thanks to Dimers' MLB picks and predictions page. There you can find probabilities and odds, and our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good!

As well as MLB game picks and predicitons, we also provide the best MLB prop bets for today, with our projections for home runs, RBIs, and more lined up against the sportsbook odds every single day of the MLB season.

Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the World Series, with our data-led probabilities paired with the best odds available.