Orioles vs. Red Sox Prediction and Odds - Sep 28, 2022

The Boston Red Sox face the Baltimore Orioles in MLB action at Fenway Park on Wednesday, starting at 7:10PM ET.

The Red Sox will send Rich Hill (7-7, 4.65 ERA) to the mound, while the Orioles will counter with Dean Kremer (8-5, 3.07 ERA).

Dimers' best betting picks for Orioles vs. Red Sox, as well as game predictions and best odds, are detailed in this article.

Who will win Orioles vs. Red Sox?

Based on high-tech computer power and data, Dimers.com has simulated Wednesday's Orioles-Red Sox MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Red Sox a 58% chance of defeating the Orioles.

More: Free Betting Guide for Orioles vs. Red Sox

Orioles vs. Red Sox Game Odds

• Run Line: Red Sox -1.5 (+150), Orioles +1.5 (-175)
• Moneyline: Red Sox -135, Orioles +116
• Total: Over/Under 9 (-114/-105)

Run Line, Moneyline and Over/Under

The Red Sox are currently -1.5 favorites versus the Orioles, with +150 at DraftKings Sportsbook the best odds currently available.

For the underdog Orioles (+1.5) to cover the run line, BetMGM has the best odds currently on the market at -175.

BetMGM currently has the best moneyline odds for the Red Sox at -135, which means you can risk $135 to win $100, for a total payout of $235, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Orioles at +116, where you can bet $100 to profit $116, earning a total payout of $216, if they win.

The Over/Under for total runs scored is set at 9 with FanDuel Sportsbook, which currently has the best odds for the Over at -114, while BetMGM currently has the best odds for the Under at -105.

As always, check out all of the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 61% chance of covering the run line, while the 9-run Over/Under is a 56% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Orioles vs. Red Sox

• Run Line: Red Sox -1.5 @ +150 via DraftKings Sportsbook
• Moneyline: Red Sox @ -135 via BetMGM (58% probability)
• Total: Over 9 @ -114 via FanDuel Sportsbook (56% probability)

Dimers' best bets are based on complex simulations and wagering expertise to serve you the best possible plays 24/7/365.

Although the Orioles are more likely to cover the run line, our best bet of Red Sox -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Orioles vs. Red Sox Prediction

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Dimers has full coverage of Wednesday's Orioles-Red Sox matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep checking this article for any changes to our betting insights before Orioles vs. Red Sox on Wednesday September 28, 2022.

Orioles vs. Red Sox 2022 Game Info

Wednesday's matchup between the Red Sox and Orioles at Fenway Park is scheduled to start at 7:10PM ET.

• Who: Baltimore Orioles vs. Boston Red Sox
• Date: Wednesday September 28, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Fenway Park

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