Orioles vs. Red Sox Prediction and Odds - Sep 26, 2022

The Boston Red Sox square off with the Baltimore Orioles in MLB action at Fenway Park on Monday, commencing at 7:10PM ET.

Connor Seabold (0-3, 10.47 ERA) will start for the Red Sox, while the Orioles are going with Jordan Lyles (11-11, 4.50 ERA).

Dimers' best betting picks for Orioles vs. Red Sox, plus game predictions and best odds, are detailed in this article.

Who will win Orioles vs. Red Sox?

Using advanced machine learning and data, Dimers.com has simulated Monday's Orioles-Red Sox MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Red Sox a 54% chance of defeating the Orioles.

More: Orioles vs. Red Sox Simulated 10,000 Times

Orioles vs. Red Sox Game Odds

• Moneyline: Red Sox -120, Orioles +106
• Total: Over/Under 9.5 (-120/+100)

Run Line, Moneyline and Over/Under

BetMGM currently has the best moneyline odds for the Red Sox at -120. That means you can risk $120 to win $100, for a total payout of $220, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Orioles at +106, where you can bet $100 to profit $106, earning a total payout of $206, if they win.

The Over/Under for total runs scored is set at 9.5 with BetMGM, which currently has the best odds for the Over at -120, as well as the best odds for the Under at +100.

As always, check out all of the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Over/Under total of 9.5 runs is a 56% chance of going Over.

More: Free Prop Picks

Best Bets for Orioles vs. Red Sox

• Moneyline: Red Sox @ -120 via BetMGM (54% probability)
• Total: Over 9.5 @ -120 via BetMGM (56% probability)

Our best bets are based on detailed simulations and betting intelligence to help you make smarter investments with your state's legal sportsbooks.

Orioles vs. Red Sox Prediction

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Dimers has full coverage of Monday's Orioles-Red Sox matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep checking this article for the latest betting analysis ahead of Orioles vs. Red Sox on Monday September 26, 2022.

Orioles vs. Red Sox 2022 Game Info

Monday's game between the Red Sox and Orioles at Fenway Park is scheduled to begin at 7:10PM ET.

• Who: Baltimore Orioles vs. Boston Red Sox
• Date: Monday September 26, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Fenway Park

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Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.