Orioles vs. Angels Prediction and Odds - Apr 22, 2022

MLB action continues on Friday at 9:38PM ET as the Baltimore Orioles square off with the Los Angeles Angels at Angel Stadium.

Reid Detmers (0-0, 8.59 ERA) will get the ball for the Angels, while the Orioles will counter with Bruce Zimmermann (0-0, 0.00 ERA).

Dimers' best betting picks for Orioles vs. Angels, as well as game predictions and best odds, are detailed below.

Who will win Orioles vs. Angels?

Using trusted computer power and data, Dimers.com has simulated Friday's Orioles-Angels MLB matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Angels a 61% chance of getting the W against the Orioles.

More: Orioles vs. Angels Simulated 10K Times

Orioles vs. Angels Current Odds

• Run Line: Angels -1.5 (+110), Orioles +1.5 (-125)
• Moneyline: Angels -175, Orioles +160
• Total: Over/Under 8.5 (-105/-105)

Run Line, Moneyline and Over/Under

The Angels are currently -1.5 favorites against the Orioles, with +110 at BetMGM the best odds currently available.

For the underdog Orioles (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -125.

BetMGM currently has the best moneyline odds for the Angels at -175. That means you can risk $175 to win $100, for a total payout of $275, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Orioles at +160, where you can bet $100 to profit $160, earning a total payout of $260, if they win.

The Over/Under sits at 8.5 with PointsBet, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -105.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 56% chance of covering the run line, while the 8.5-run Over/Under is a 51% chance of going Under.

More: Today's Best Bets for All Major Sports

Best Bets for Orioles vs. Angels

• Run Line: Orioles +1.5 @ -125 via DraftKings Sportsbook (56% probability)
• Moneyline: Orioles @ +160 via FanDuel Sportsbook (0.6% edge)
• Total: Under 8.5 @ -105 via Caesars Sportsbook (51% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to help you make more informed investments with the legal sportsbooks in America.

While the Angels are more likely to win the game, according to DimersBOT, betting on the Orioles moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen here at Dimers.com is pivotal to being profitable in the long run.

Orioles vs. Angels Probabilities

Use our interactive widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Baltimore vs. LA Angels, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Friday's Orioles-Angels matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates often, so check this page for the latest betting analysis before Orioles vs. Angels on Friday April 22, 2022.

Best Betting Promo for Orioles vs. Angels

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Orioles vs. Angels 2022 Game Info

When do the Angels play the Orioles?

• Date: Friday April 22, 2022
• Time: 9:38PM ET / 6:38PM PT
• Venue: Angel Stadium

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Want more MLB analysis like this?

To get more MLB betting predictions like you've just read for Orioles vs. Angels, all you've gotta do is visit Dimers' MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can produce the most comprehensive MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.