Ole Miss vs. Michigan State Prediction: Michigan State Predicted to Win NCAA Tournament Sweet Sixteen Matchup [3/28/2025]

March Madness action continues on Friday at 7:09PM ET as Ole Miss takes on Michigan State in college basketball action at State Farm Arena.

Based on updated simulations, Dimers' advanced college basketball model (see Dimers Pro for full access) projects Michigan State as the most likely winner of today's game.

Check the latest March Madness player prop projections and 2025 NCAA Championship probabilities from our expert team.

"Employing the latest data, our experts simulated Friday's Ole Miss-Michigan State game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict Michigan State's chance of winning is 64%, while Ole Miss' is 36%."

For further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Ole Miss vs. Michigan State predictions page.

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Ole Miss vs. Michigan State Prediction: Who Will Win and Advance to the Elite Eight?

Using innovative machine learning and data, we have simulated the result of Friday's NCAA Tournament game between Ole Miss and Michigan State 10,000 times as part of our March Madness predictions coverage.

Our famous predictive model gives Michigan State a 64% chance of defeating Ole Miss. Our predicted final score has Michigan State winning 75-71.

According to our model, Ole Miss (+3.5) has a 51% chance of covering the spread, while the 144.5-point over/under has a 53% chance of going over.

Ole Miss vs. Michigan State March Madness Odds

We have sourced the best March Madness odds in America for this Sweet 16 game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Boost your betting this month with the top March Madness betting sites and March Madness betting promos, sourced from top sportsbooks and DFS operators.

Ole Miss vs. Michigan State Picks and Best Bets

Our model's biggest edge in today's Ole Miss vs. Michigan State matchup is on the spread.

Our expert predictions, matched against the best odds, reveal the best March Madness picks and March Madness best bets for every game throughout the tournament.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Ole Miss vs. Michigan State Game-Day Updates and Essential Details

Friday's college basketball game between Michigan State and Ole Miss at State Farm Arena is scheduled to commence at 7:09PM ET.

• Who: Ole Miss vs. Michigan State
• Date: Friday, March 28, 2025
• Time: 7:09PM ET/4:09PM PT
• Venue: State Farm Arena
• March Madness Stage: Sweet 16

Dimers.com's full preview of Friday's Ole Miss vs. Michigan State matchup includes our prediction, picks and the latest betting odds.

Before making any Ole Miss vs. Michigan State picks, be sure to check out the latest March Madness predictions and betting advice from Dimers Pro.

Key March Madness Guides and Insights

• Learn about NCAA Championship history and the lowest-seeded team to ever win March Madness
• Get answers to legal questions, including which states you can legally bet on college sports and the minimum age required to place a bet on March Madness
• A breakdown of March Madness futures bets and popular prop bets for the NCAA tournament
• Explore strategy with guides on identifying value bets during the tournament and betting on individual player awards like Tournament MVP
• Understand the tournament format, including how many games are played in March Madness and how venue locations impact teams when playing at neutral sites

Conclusion

We predict Michigan State, with a 64% win probability, will likely beat Ole Miss on Friday.

AI and automation have enhanced this article to quickly deliver accurate Ole Miss vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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