Ohio State vs. Notre Dame Prediction: Ohio State Predicted to Win College Football Playoff National Championship [2025]

Notre Dame and Ohio State will meet in the 2025 College Football Playoff National Championship at Mercedes-Benz Stadium on Monday, commencing at 7:30PM ET.

Based on updated simulation results, Dimers' advanced college football model (see Dimers Pro for full access) predicts Ohio State as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Ohio State-Notre Dame game 10,000 times," said Ryan Leaver from Dimers.

"Incorporating recent updates and thousands of additional inputs, our prediction shows Ohio State is likely to win, with a probability of 65%, compared to Notre Dame's 35%."

For further insights into Monday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive Ohio State vs. Notre Dame predictions page.

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Ohio State vs. Notre Dame Game-Day Updates and Essential Details

Monday's college football game between Notre Dame and Ohio State at Mercedes-Benz Stadium is scheduled to commence at 7:30PM ET.

• Who: Ohio State vs. Notre Dame
• Date: Monday, January 20, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Mercedes-Benz Stadium
• Tickets: Get tickets for the game on Ticketmaster

Dimers.com's comprehensive preview of Monday's Ohio State vs. Notre Dame matchup includes our prediction, picks and the latest betting odds.

Before making any Ohio State vs. Notre Dame picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

College Football Playoff National Championship Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data, we have simulated the result of the 2025 College Football Playoff National Championship 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Ohio State a 65% chance of defeating Notre Dame. Our predicted final score has Ohio State winning 26-21.

According to our model, Notre Dame (+8.5) has a 60% chance of covering the spread, while the over/under total of 45.5 points has a 55% chance of going over.

College Football Playoff National Championship Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Ohio State	Notre Dame
Spread	-8.5 (-110)	+8.5 (-110)
Moneyline	-350	+310
Total	o45.5 (-110)	u45.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Ohio State vs. Notre Dame Picks

Our model's biggest edge in today's Ohio State vs. Notre Dame matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best college football picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Conclusion

We predict Ohio State, with a 65% win probability, will likely beat Notre Dame on Monday.

AI and automation have enhanced this article to quickly deliver accurate Ohio State vs. Notre Dame insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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