Ohio State vs. Northwestern CFB Prediction and Odds - Nov 5, 2022

Northwestern and Ohio State meet in College Football action at Ryan Field on Saturday, with kickoff at 12:00PM ET.

Dimers' top betting picks for Ohio State vs. Northwestern, plus game predictions and betting odds, are featured in this article.

Who will win Ohio State vs. Northwestern?

Using state-of-the-art machine learning and data, Dimers.com has simulated Ohio State vs. Northwestern 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives Ohio State a 99% chance of getting the W against Northwestern.

More: Ohio State vs. Northwestern Simulated 10K Times

Ohio State vs. Northwestern Odds

• Spread: Northwestern +37.5 (-105), Ohio State -37.5 (-110)
• Moneyline: Northwestern +8000, Ohio State -100000
• Total: Over/Under 55 (+100/-105)

Point Spread, Moneyline and Over/Under

Northwestern is currently the +37.5 underdog against Ohio State, with -105 at FanDuel Sportsbook the best odds currently available.

For the favored Ohio State (-37.5) to cover the spread, Caesars Sportsbook has the best odds currently on the market at -110.

FanDuel Sportsbook currently has the best moneyline odds for Northwestern at +8000. That means you can bet $100 to profit $8,000, earning a total payout of $8,100, if it wins.

On the other hand, FanDuel Sportsbook also has the best moneyline odds for Ohio State at -100000, where you can risk $100,000 to win $100, for a total payout of $100,100, if it comes out on top.

The Over/Under for total points scored is set at 55 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, while PointsBet currently has the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, the bookmakers have got it right and both Ohio State and Northwestern are a 50% chance of covering the spread, while the Over/Under total of 55 points is a 51% chance of going Over.

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Best Bets for Ohio State vs. Northwestern

• Spread: Northwestern +37.5 @ -105 via FanDuel Sportsbook (50% probability)
• Moneyline: Northwestern @ +8000 via FanDuel Sportsbook
• Total: Over 55 @ +100 via DraftKings Sportsbook (51% probability)

Dimers' best bets are based on complex simulations and betting expertise to help you make better decisions with your state's legal sportsbooks.

While Ohio State is more likely to win the game, according to DimersBOT, betting on Northwestern moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers.com is one of the keys to being a profitable sports bettor in the long run.

Ohio State vs. Northwestern Prediction

Dimers.com's predicted final score for Ohio State vs. Northwestern at Ryan Field this Saturday has Ohio State winning 46-9.

Click or tap on See Matchup for more.

Dimers has full coverage of this week's Ohio State-Northwestern matchup, including pregame predictions, computer picks, and live updates.

Remember, DimersBOT updates frequently, so refresh this page for the latest betting analysis ahead of Ohio State vs. Northwestern on Saturday November 5, 2022.

Ohio State vs. Northwestern 2022 CFB Game Info

Saturday's action between Northwestern and Ohio State in College Football at Ryan Field is scheduled to begin at 12:00PM ET.

• Who: Ohio State vs. Northwestern
• Date: Saturday November 5, 2022
• Time: 12:00PM ET / 9:00AM PT
• Venue: Ryan Field

Looking to join an online sportsbook and start betting on College Football now? Check out the best sports betting offers in your state.

What College Football games are on this week?

Now you've got the 411 on Ohio State vs. Northwestern, see the latest betting predictions for all upcoming NCAA Football games in Dimers' College Football Bet Hub. There you can find probabilities and odds, and our best bets for every single CFB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!