Ohio State vs. Michigan State CFB Prediction and Odds - Oct 8, 2022

Michigan State faces the favored Ohio State in College Football action at Spartan Stadium on Saturday, commencing at 4:00PM ET.

Dimers' best betting picks for Ohio State vs. Michigan State, plus game predictions and betting odds, are detailed below.

Who will win Ohio State vs. Michigan State?

Using high-tech machine learning and data, Dimers.com has simulated Ohio State vs. Michigan State 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives Ohio State a 93% chance of beating Michigan State.

More: Ohio State vs. Michigan State Simulated 10K Times

Ohio State vs. Michigan State Current Odds

• Spread: Michigan State +27 (-107), Ohio State -27 (-107)
• Moneyline: Michigan State +1800, Ohio State -4000
• Total: Over/Under 64.5 (-106/-107)

Point Spread, Moneyline and Over/Under

Michigan State is the +27 underdog against Ohio State, with -107 at PointsBet the best odds currently available.

For the favored Ohio State (-27) to cover the spread, PointsBet also has the best odds currently on offer at -107.

Caesars Sportsbook currently has the best moneyline odds for Michigan State at +1800. That means you can bet $100 to profit $1,800, earning a total payout of $1,900, if it wins.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for Ohio State at -4000, where you can risk $4,000 to win $100, for a total payout of $4,100, if it comes out on top.

The Over/Under sits at 64.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -106, while PointsBet currently has the best odds for the Under at -107.

As always, make sure you check all the sportsbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Ohio State (-27) is a 51% chance of covering the spread, while the Over/Under total of 64.5 points is a 55% chance of going Under.

More: Best Prop Bets Today

Best Bets for Ohio State vs. Michigan State

• Spread: Ohio State -27 @ -107 via PointsBet (51% probability)
• Moneyline: Michigan State @ +1800 via Caesars Sportsbook (1.3% edge)
• Total: Under 64.5 @ -107 via PointsBet (55% probability)

Our best bets are based on detailed modeling and wagering expertise to help you make smarter decisions with your state's legal sportsbooks.

While Ohio State is more likely to win the game, according to DimersBOT, taking Michigan State moneyline is the best option due to the 1.3% edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen on Dimers is one of the keys to being a profitable sports bettor in the long run.

Ohio State vs. Michigan State Prediction

Dimers.com's predicted final score for Ohio State vs. Michigan State at Spartan Stadium this Saturday has Ohio State winning 44-17.

Click or tap on See Matchup to reveal more.

Dimers has full betting coverage of this week's Ohio State-Michigan State matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so refresh this page for the latest betting analysis before Ohio State vs. Michigan State on Saturday October 8, 2022.

Ohio State vs. Michigan State 2022 CFB Game Info

Saturday's matchup between Michigan State and Ohio State in College Football at Spartan Stadium is scheduled to commence at 4:00PM ET.

• Who: Ohio State vs. Michigan State
• Date: Saturday October 8, 2022
• Time: 4:00PM ET / 1:00PM PT
• Venue: Spartan Stadium

Want to join an online sportsbook and start betting on College Football? We've listed the best available sign-up offers in every legal betting state.

Want more College Football previews like this?

To get more NCAA Football betting predictions like you've just read for Ohio State vs. Michigan State, all you've gotta do is visit Dimers' College Football Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can produce the best CFB betting previews available. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.