Notre Dame vs. Syracuse CFB Prediction and Odds - Oct 29, 2022

Syracuse and Notre Dame clash in College Football action at JMA Wireless Dome on Saturday, commencing at 12:00PM ET.

Dimers' top betting picks for Notre Dame vs. Syracuse, plus game predictions and betting odds, are featured below.

Who will win Notre Dame vs. Syracuse?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Notre Dame vs. Syracuse 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives Syracuse a 61% chance of defeating Notre Dame.

More: Full Betting Analysis for Notre Dame vs. Syracuse

Notre Dame vs. Syracuse Odds

• Spread: Syracuse 0 (-110), Notre Dame -0 (-110)
• Moneyline: Syracuse +104, Notre Dame -105
• Total: Over/Under 47.5 (-110/-110)

Point Spread, Moneyline and Over/Under

FanDuel Sportsbook currently has the best moneyline odds for Syracuse at +104, which means you can bet $100 to profit $104, earning a total payout of $204, if it wins.

Meanwhile, PointsBet currently has the best moneyline odds for Notre Dame at -105, where you can risk $105 to win $100, for a total payout of $205, if it comes out on top.

The Over/Under for total points scored sits at 47.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all the online sportsbooks available in your state for the best College Football odds and lines.

According to DimersBOT, the 47.5-point Over/Under is a 52% chance of going Over.

More: Best Free Bet Tracking Tool

Best Bets for Notre Dame vs. Syracuse

• Spread: Syracuse 0 @ -110 via Caesars Sportsbook (60% probability) 🔥
• Moneyline: Syracuse @ +104 via FanDuel Sportsbook (61% probability) 🔥
• Total: Over 47.5 @ -110 via FanDuel Sportsbook (52% probability)

Any time you see a 🔥, that means you've found one of our best bets today across any sport.

Dimers' best bets are based on detailed modeling and betting expertise to serve you the best possible plays 24/7/365.

Notre Dame vs. Syracuse Prediction

Dimers.com's predicted final score for Notre Dame vs. Syracuse at JMA Wireless Dome on Saturday has Syracuse winning 25-22.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Notre Dame-Syracuse matchup, including pregame predictions, free picks, and live scores.

Remember, DimersBOT updates frequently, so keep checking this article for any changes to our betting analysis ahead of Notre Dame vs. Syracuse on Saturday October 29, 2022.

Notre Dame vs. Syracuse 2022 CFB Game Info

Saturday's matchup between Syracuse and Notre Dame in College Football at JMA Wireless Dome is scheduled to begin at 12:00PM ET.

• Who: Notre Dame vs. Syracuse
• Date: Saturday October 29, 2022
• Time: 12:00PM ET / 9:00AM PT
• Venue: JMA Wireless Dome

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We use the power of predictive analytics to find value in the markets so we can produce the most comprehensive CFB betting previews out there. We do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.