Notre Dame vs. Louisville CFB Prediction and Odds - October 7, 2023

Louisville and Notre Dame clash in College Football action at L&N Federal Credit Union Stadium on Saturday, starting at 7:30PM ET.

Dimers' top betting picks for Notre Dame vs. Louisville, as well as game predictions and best odds, are featured below.

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Who Will Win: Notre Dame vs. Louisville

Based on high-tech machine learning and data, Dimers.com has simulated Notre Dame vs. Louisville 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives Notre Dame a 67% chance of beating Louisville.

More: Betting Analysis for Notre Dame vs. Louisville

Notre Dame vs. Louisville Odds

• Spread: Louisville +6.5 (-110), Notre Dame -6.5 (+100)
• Moneyline: Louisville +205, Notre Dame -230
• Total: Over/Under 53.5 (-110/-105)

Louisville is currently the +6.5 underdog against Notre Dame, with -110 at DraftKings Sportsbook the best odds currently available.

For the favored Notre Dame (-6.5) to cover the spread, FanDuel Sportsbook has the best odds currently on offer at +100.

DraftKings Sportsbook currently has the best moneyline odds for Louisville at +205. That means you can bet $100 to profit $205, earning a total payout of $305, if it wins.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for Notre Dame at -230, where you can risk $230 to win $100, for a total payout of $330, if it comes out on top.

The Over/Under sits at 53.5 with PointsBet, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, check out all the online sportsbooks that are available in your state for the best College Football odds and lines.

According to DimersBOT, the bookmakers have got it right and both Notre Dame and Louisville have a 50% chance of covering the spread, while the 53.5-point Over/Under also has an equal 50-50 chance of hitting.

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More: Free Prop Picks

Best Bets: Notre Dame vs. Louisville

• Spread: Notre Dame -6.5 @ +100 via FanDuel Sportsbook (50% probability)
• Moneyline: Louisville @ +205 via DraftKings Sportsbook
• Total: Under 53.5 @ -105 via FanDuel Sportsbook (50% probability)

Dimers' best bets are based on detailed modeling and wagering expertise to help you make more informed decisions with the legal sportsbooks in America.

While Notre Dame is more likely to win the game, according to DimersBOT, taking Louisville moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers is pivotal to achieving long-term profitability.

Notre Dame vs. Louisville Prediction

Dimers.com's predicted final score for Notre Dame vs. Louisville at L&N Federal Credit Union Stadium this Saturday has Notre Dame winning 30-23.

Click or tap on See Matchup for more information.

Dimers has full betting coverage of this week's Notre Dame-Louisville game, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this article for the latest betting insights ahead of Notre Dame vs. Louisville on Saturday October 7, 2023.

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Notre Dame vs. Louisville 2023

Saturday's action between Louisville and Notre Dame in College Football at L&N Federal Credit Union Stadium is scheduled to start at 7:30PM ET.

• Who: Notre Dame vs. Louisville
• Date: Saturday October 7, 2023
• Time: 7:30PM ET / 4:30PM PT
• Venue: L&N Federal Credit Union Stadium

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Make Informed Sports Betting Decisions with Dimers

Dimers' predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Notre Dame vs. Louisville predictions can help you make informed decisions, it's vital that you gamble responsibly and manage your bankroll effectively.

To increase your ability to be a responsible gambler, we recommended reading this full guide to Kentucky sports betting as well as utilizing these .Kentucky sportsbook promos that can get you started off on the right foot.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What College Football Games Are on This Week?

Notre Dame and Louisville aren't the only two NCAA Football teams you can bet on tonight. DimersBOT never stops and we've got picks and best bets for each and every CFB game via our College Football predictions. Not only do we provide with you top-notch predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out now!

In addition to our leading CFB predictions, we also feature the best CFB prop bets today, projecting passing yards, touchdowns, and more against the best odds available every day of the CFB season.