Notre Dame vs. Duke CFB Prediction and Odds - September 30, 2023

Duke and Notre Dame lock horns in College Football action at Brooks Field at Wallace Wade Stadium on Saturday, with kickoff at 7:30PM ET.

Dimers' best betting picks for Notre Dame vs. Duke, plus our score prediction and betting odds, are featured below.

This Notre Dame vs. Duke betting preview is presented by Bet365, which has a Bet $1, Get $365 in Bonus Bets offer for new users.

Who Will Win: Notre Dame vs. Duke

Based on trusted computer power and data, Dimers.com has simulated Notre Dame vs. Duke 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives Notre Dame a 55% chance of beating Duke.

More: Notre Dame vs. Duke Simulated 10,000 Times

Notre Dame vs. Duke Odds

• Spread: Duke +5.5 (-110), Notre Dame -5.5 (-105)
• Moneyline: Duke +185, Notre Dame -194
• Total: Over/Under 52.5 (-110/-105)

Duke is currently the +5.5 underdog against Notre Dame, with -110 at PointsBet the best odds currently available.

For the favored Notre Dame (-5.5) to cover the spread, FanDuel Sportsbook has the best odds currently on the market at -105.

DraftKings Sportsbook currently has the best moneyline odds for Duke at +185, which means you can throw down $100 to profit $185, earning a total payout of $285, if it wins.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for Notre Dame at -194, where you can risk $194 to win $100, for a total payout of $294, if it comes out on top.

The Over/Under for total points scored is set at 52.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check all the legal sportbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Duke (+5.5) has a 63% chance of covering the spread, while the Over/Under total of 52.5 points has a 52% chance of going Over.

More: Free Prop Picks

Best Bets: Notre Dame vs. Duke

• Spread: Duke +5.5 @ -110 via PointsBet (63% probability) 🔥
• Moneyline: Duke @ +185 via DraftKings Sportsbook (10.3% edge) 🔥
• Total: Over 52.5 @ -110 via DraftKings Sportsbook (52% probability)

Every time you see a 🔥, you know you've found one of our best free picks of the day across all major pro and college sports.

Dimers' best bets are based on complex modeling and wagering expertise to help you make better decisions with your state's legal sportsbooks.

While Notre Dame is more likely to win the game, according to DimersBOT, betting on Duke moneyline is the best option due to the 10.3% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen here at Dimers is crucial to being profitable in the long run.

Notre Dame vs. Duke Prediction

Dimers.com's predicted final score for Notre Dame vs. Duke at Brooks Field at Wallace Wade Stadium on Saturday has Notre Dame winning 27-25.

Click or tap on See Matchup to find out more.

Dimers has full betting coverage of this week's Notre Dame-Duke game, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep checking this page for any changes to our betting insights before Notre Dame vs. Duke on Saturday September 30, 2023.

Another great way to make the most of this Notre Dame vs. Duke game is by using the latest DraftKings promo, where a bet as small as $5 guarantees you $200 in bonus bets.

Notre Dame vs. Duke 2023

Saturday's action between Duke and Notre Dame in College Football at Brooks Field at Wallace Wade Stadium is scheduled to start at 7:30PM ET.

• Who: Notre Dame vs. Duke
• Date: Saturday September 30, 2023
• Time: 7:30PM ET / 4:30PM PT
• Venue: Brooks Field at Wallace Wade Stadium

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Make Informed Sports Betting Decisions Today

Our picks are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Notre Dame vs. Duke picks can help you make informed decisions, it's important that you only bet what you can afford to lose and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More College Football Previews Like This?

To get more NCAA Football betting predictions like you've just read for Notre Dame vs. Duke, all you've gotta do is visit Dimers' College Football Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can write the most comprehensive CFB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – check out our College Football picks and predictions.

In addition to our leading CFB predictions, we also feature the best CFB prop bets today, projecting passing yards, touchdowns, and more against the top odds available every single day of the CFB season.