Notre Dame vs. Clemson CFB Prediction and Odds - November 4, 2023

Clemson squares off with Notre Dame in College Football action at Memorial Stadium on Saturday, commencing at 12:00PM ET.

Dimers' prediction for Saturday's Notre Dame vs. Clemson matchup, as well as the latest odds and our full game preview, are detailed below.

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Who Will Win: Notre Dame vs. Clemson

Using trusted computer power and data, Dimers.com has simulated the outcome of Notre Dame vs. Clemson 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives Clemson a 51% chance of defeating Notre Dame.

More: Notre Dame vs. Clemson Simulated 10K Times

Notre Dame vs. Clemson Odds

We have sourced the best betting odds in America for this game, which are listed here:

• Spread: Clemson +3.5 (-110), Notre Dame -3.5 (-105)
• Moneyline: Clemson +150, Notre Dame -170
• Total: Over/Under 43 (-110/-110)

Odds are correct at the time of publication and subject to change.

Clemson is currently the +3.5 underdog versus Notre Dame, with -110 at DraftKings Sportsbook the best odds currently available.

For the favored Notre Dame (-3.5) to cover the spread, PointsBet has the best odds currently on the market at -105.

PointsBet currently has the best moneyline odds for Clemson at +150, which means you can bet $100 to profit $150, earning a total payout of $250, if it wins.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for Notre Dame at -170, where you can risk $170 to win $100, for a total payout of $270, if it comes out on top.

The Over/Under is set at 43 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, Clemson (+3.5) has a 61% chance of covering the spread, while the Over/Under total of 43 points has a 57% chance of going Over.

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More: Best Prop Bets Today

Best Bets: Notre Dame vs. Clemson

• Spread: Clemson +3.5 @ -110 via DraftKings Sportsbook (61% probability) 🔥
• Moneyline: Clemson @ +150 via PointsBet (51% probability) 🔥
• Total: Over 43 @ -110 via PointsBet (57% probability) 🔥

Every time you see a 🔥, that means it's one of our best free picks today across all major pro and college sports.

Dimers' best bets are based on complex modeling and gambling expertise to bring you the best possible plays every time.

Notre Dame vs. Clemson Prediction

Dimers.com's predicted final score for Notre Dame vs. Clemson at Memorial Stadium this Saturday has Clemson winning 23-22.

Click or tap on See Matchup to find out more.

Dimers has full coverage of this week's Notre Dame vs. Clemson game, including pregame predictions, free picks, and live updates.

Remember, DimersBOT updates often, so keep checking this article for any changes to our betting analysis ahead of Notre Dame vs. Clemson on Saturday November 4, 2023.

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Notre Dame vs. Clemson Preview

Saturday's action between Clemson and Notre Dame in College Football at Memorial Stadium is scheduled to commence at 12:00PM ET.

• Who: Notre Dame vs. Clemson
• Date: Saturday November 4, 2023
• Time: 12:00PM ET / 9:00AM PT
• Venue: Memorial Stadium

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Conclusion

This detailed game preview centers around our Notre Dame vs. Clemson prediction and College Football odds.

Our picks are made after 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Notre Dame vs. Clemson picks can help you make informed decisions, it's crucial that you only bet what you can afford to lose and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More CFB Previews Like This?

So, you liked our Notre Dame vs. Clemson betting analysis? Awesome. Did you know our College Football Betting News page has a detailed betting preview for every CFB matchup as soon as the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find value in the markets. This allows us to create the most reliable CFB betting previews and beat the public and the sportsbooks to the punch.

In addition to our leading CFB predictions, we also feature the best CFB prop bets today, projecting passing yards, touchdowns, and more against the best odds available every day of the CFB season.