NFL Week 16 Preview: Game Information and Odds for Every Matchup [2024]

As the NFL 2024 season heads toward the playoffs, Week 16 brings another exciting slate of games with major postseason implications. With pivotal matchups spanning from Thursday night to Monday night, every game is a must-watch for football fans and bettors alike. 

This preview gives you all the key game details and betting insights you need to prepare for an action-packed week.

Dimers.com will be providing in-depth Week 16 coverage all week long, including straight-up picks, picks against the spread, best bets, player props, and touchdown scorer predictions.

Check out our NFL predictions throughout the week for continuously updated odds, probabilities, and projections.

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Cleveland Browns vs. Cincinnati Bengals

• Matchup: Browns vs. Bengals
• Date: Thursday, December 19, 2024
• Time: 8:15 PM ET
• Venue: Paycor Stadium
• Spread: Bengals -3.5
• Total (Over/Under): 45.5
• Moneyline Odds: Browns +150, Bengals -180

Houston Texans vs. Kansas City Chiefs

• Matchup: Texans vs. Chiefs
• Date: Saturday, December 21, 2024
• Time: 1:00 PM ET
• Venue: GEHA Field at Arrowhead Stadium
• Spread: Chiefs -4.5
• Total (Over/Under): 47
• Moneyline Odds: Texans +170, Chiefs -205

Pittsburgh Steelers vs. Baltimore Ravens

• Matchup: Steelers vs. Ravens
• Date: Saturday, December 21, 2024
• Time: 4:30 PM ET
• Venue: M&T Bank Stadium
• Spread: Ravens -5.5
• Total (Over/Under): 42.5
• Moneyline Odds: Steelers +195, Ravens -238

New York Giants vs. Atlanta Falcons

• Matchup: Giants vs. Falcons
• Date: Sunday, December 22, 2024
• Time: 1:00 PM ET
• Venue: Mercedes-Benz Stadium
• Spread: Falcons -4.5
• Total (Over/Under): 44.5
• Moneyline Odds: Giants +170, Falcons -205

New England Patriots vs. Buffalo Bills

• Matchup: Patriots vs. Bills
• Date: Sunday, December 22, 2024
• Time: 1:00 PM ET
• Venue: Highmark Stadium
• Spread: Bills -8.5
• Total (Over/Under): 44.5
• Moneyline Odds: Patriots +320, Bills -410

Detroit Lions vs. Chicago Bears

• Matchup: Lions vs. Bears
• Date: Sunday, December 22, 2024
• Time: 1:00 PM ET
• Venue: Soldier Field
• Spread: Lions -1
• Total (Over/Under): 47
• Moneyline Odds: Lions -110, Bears -110

Tennessee Titans vs. Indianapolis Colts

• Matchup: Titans vs. Colts
• Date: Sunday, December 22, 2024
• Time: 1:00 PM ET
• Venue: Lucas Oil Stadium
• Spread: Colts -4
• Total (Over/Under): 45.5
• Moneyline Odds: Titans +160, Colts -192

Arizona Cardinals vs. Carolina Panthers

• Matchup: Cardinals vs. Panthers
• Date: Sunday, December 22, 2024
• Time: 1:00 PM ET
• Venue: Bank of America Stadium
• Spread: Cardinals -1
• Total (Over/Under): 45.5
• Moneyline Odds: Cardinals -118, Panthers -102

Philadelphia Eagles vs. Washington Commanders

• Matchup: Eagles vs. Commanders
• Date: Sunday, December 22, 2024
• Time: 1:00 PM ET
• Venue: Northwest Stadium
• Spread: Eagles -3.5
• Total (Over/Under): 45
• Moneyline Odds: Eagles -170, Commanders +142

Los Angeles Rams vs. New York Jets

• Matchup: Rams vs. Jets
• Date: Sunday, December 22, 2024
• Time: 1:00 PM ET
• Venue: MetLife Stadium
• Spread: Jets -3
• Total (Over/Under): 47.5
• Moneyline Odds: Rams +130, Jets -155

Minnesota Vikings vs. Seattle Seahawks

• Matchup: Vikings vs. Seahawks
• Date: Sunday, December 22, 2024
• Time: 4:05 PM ET
• Venue: Lumen Field
• Spread: Seahawks -3
• Total (Over/Under): 45.5
• Moneyline Odds: Vikings +130, Seahawks -155

Denver Broncos vs. Los Angeles Chargers

• Matchup: Broncos vs. Chargers
• Date: Sunday, December 22, 2024
• Time: 4:05 PM ET
• Venue: SoFi Stadium
• Spread: Chargers -4
• Total (Over/Under): 43
• Moneyline Odds: Broncos +160, Chargers -192

Jacksonville Jaguars vs. Las Vegas Raiders

• Matchup: Jaguars vs. Raiders
• Date: Sunday, December 22, 2024
• Time: 4:25 PM ET
• Venue: Allegiant Stadium
• Spread: Jaguars -1
• Total (Over/Under): 45.5
• Moneyline Odds: Jaguars -112, Raiders -108

San Francisco 49ers vs. Miami Dolphins

• Matchup: 49ers vs. Dolphins
• Date: Sunday, December 22, 2024
• Time: 4:25 PM ET
• Venue: Hard Rock Stadium
• Spread: 49ers -1
• Total (Over/Under): 49
• Moneyline Odds: 49ers -118, Dolphins -102

Tampa Bay Buccaneers vs. Dallas Cowboys

• Matchup: Buccaneers vs. Cowboys
• Date: Sunday, December 22, 2024
• Time: 8:20 PM ET
• Venue: AT&T Stadium
• Spread: Cowboys -4.5
• Total (Over/Under): 46.5
• Moneyline Odds: Buccaneers +180, Cowboys -218

New Orleans Saints vs. Green Bay Packers

• Matchup: Saints vs. Packers
• Date: Monday, December 23, 2024
• Time: 8:15 PM ET
• Venue: Lambeau Field
• Spread: Packers -5
• Total (Over/Under): 45
• Moneyline Odds: Saints +180, Packers -218

Conclusion

Week 16 promises high-stakes action as teams vie for playoff spots. From Thursday night’s AFC North showdown to a thrilling Monday night game at Lambeau Field, every matchup is packed with excitement.

Stay tuned to Dimers for NFL picks, NFL prop bets, NFL trends, and Super Bowl predictions all week long.

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