NFL Probabilities: Week 7 Spreads, Moneylines & Totals

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Written by Nick Slade
Reviewed by Jason Bevilacqua
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Our NFL experts break down all the best NFL predictions that are expected to play out in an action packer Week 7.

NFL Predictions, NFL Week 7 predictions, NFL picks
Check out the best NFL predictions ahead of Week 7 action.

As the NFL season approaches its halfway point, Week 7 features some crucial matchups that will have significant implications on playoff standings. From divisional clashes to high-stakes interconference showdowns, this week promises plenty of excitement and drama. Below, we break down key predictions for Week 7, covering top win probabilities, spreads, and a comprehensive look at the most impactful games.

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Top 5 NFL Win Predictions for Week 7

Several Week 7 matchups stand out for their predicted outcomes. Topping the list are the Buffalo Bills, expected to cruise past the Tennessee Titans. Other favorites include the Washington Commanders, Los Angeles Rams, Baltimore Ravens, and New York Jets, each favored to secure victories based on solid performances and favorable matchups.

Let’s dive into the top five win predictions for Week 7 and see if they could be the perfect mix for Week 7 NFL parlay bets.

1. Bills (78%) vs. Titans

The Buffalo Bills, boasting a 78% win probability, are the strongest favorites of Week 7. Armed with Josh Allen’s dynamic offense and a defense capable of shutting down opponents, the Bills are expected to dominate the Tennessee Titans, who are struggling on offense. The -9.5 spread reflects Buffalo's superior firepower, while the Titans are backed by just 22%. This game is likely to be one-sided, with the Bills asserting themselves as one of the top teams in the AFC.

2. Commanders (74%) vs. Panthers

The Washington Commanders come in as heavy favorites with a 74% chance of winning and a -7.5 spread. Known for their solid defensive performances, the Commanders should handle the Carolina Panthers, who rank among the league’s weakest teams. The Panthers' offense has been erratic, and a matchup against Washington’s increasingly disciplined defense does not bode well for their chances of an upset.

3. Rams (73%) vs. Raiders

The Los Angeles Rams hold a 73% predicted win probability against the Las Vegas Raiders, with a -6.5 spread. Despite some inconsistencies this season, the Rams’ offense has enough potency to earn a decisive edge in this contest. The Raiders, on the other hand, have struggled with consistency, and their defense is unlikely to contain the Rams’ balanced attack.

4. Ravens (61%) vs. Buccaneers

The Baltimore Ravens are predicted to win with a 61% probability and a -3.5 spread over the Tampa Bay Buccaneers. The Ravens have been clicking on both offense and defense, while the Buccaneers continue to battle inconsistency, particularly on offense. Though the game may stay competitive, Baltimore’s overall balance gives them the edge to secure the win.

5. Jets (61%) vs. Steelers

The New York Jets are favored with a 61% chance to beat the Pittsburgh Steelers in this Sunday night showdown. Backed by a -1.5 spread, the Jets’ sound defense and recent addition of Davante Adams on offense could make the difference in what should be a tightly contested game. Meanwhile, the Steelers’ offensive struggles may continue, making it difficult for them to keep pace with New York.

MORE: Predictions for every Week 7 matchup

Key Matchups to Watch in Week 7

NFL Week 7 offers plenty of high-stakes matchups that could shift the balance of power across both conferences. Whether it’s the Chiefs and 49ers' interconference battle or divisional showdowns in the AFC North and NFC East, this week promises excitement, drama, and critical playoff implications.

Bengals (69%) vs. Browns (31%)

This AFC North showdown between the Cincinnati Bengals and Cleveland Browns could have massive implications on the division standings. The Bengals, favored with a 69% win probability, are looking to gain momentum as they push for playoff positioning after a 204 start. Joe Burrow and the Bengals’ offense will likely capitalize on the Browns’ defensive lapses, though divisional games often produce surprises. A Bengals win could thrust them back into the AFC North title race.

Eagles (64%) vs. Giants (36%)

Another divisional clash sees the Philadelphia Eagles, with a 64% win probability, take on the New York Giants. The Eagles have consistently been one of the top teams in the NFC East, and a win here would further solidify their path to contending for the division title. The Giants, despite being underdogs, could make things difficult for their division rivals, making this a game to watch closely.

Chiefs (44%) vs. 49ers (56%)

One of the most anticipated matchups of Week 7 features the Kansas City Chiefs against the San Francisco 49ers. The 49ers are slightly favored with a 56% win probability, but the Chiefs, led by Patrick Mahomes, are always a threat. This game could turn into a high-scoring shootout, and its outcome could be pivotal in the playoff races for both conferences.

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Predicted Scores and Totals for Week 7

Several games in Week 7 are predicted to be closely contested, with small margins separating the favorites from the underdogs.

Here are some key score predictions:

  • Chiefs vs. 49ers: 49ers win 24-23 (Predicted total: 47 points)
    Expect a thrilling finish as two playoff hopefuls battle it out. The Chiefs’ offensive prowess will clash with the 49ers’ strong defense in what could be a defining moment for both teams.
  • Lions vs. Vikings: Vikings win 26-24 (Predicted total: 48 points)
    This NFC North matchup could come down to the wire, with both teams capable of lighting up the scoreboard. Home-field advantage may give Minnesota the edge.
  • Ravens vs. Buccaneers: Ravens win 26-23 (Predicted total: 49 points)
    The Ravens’ offensive versatility will test the Buccaneers, who must find consistency on offense to keep pace. This game could be an offensive showcase, with early playoff implications for both teams.

Best Spread Predictions for NFL Week 7

Here are our top five spread predictions for Week 7, based on win probabilities and favorable betting lines:

  1. Cardinals +2.5 vs. Chargers
    With a 58.2% win probability, the Cardinals are a solid bet to cover the +2.5 spread. Their ability to stay in close games makes them a smart play against the inconsistent Chargers.
  2. Raiders +6.5 vs. Rams
    The Raiders are predicted to cover the spread with a 57% chance, as the Rams have shown vulnerabilities. Despite being underdogs, Las Vegas has the potential to keep this one close.
  3. Browns +5.5 vs. Bengals
    In a divisional game where anything can happen, the Browns covering a +5.5 spread feels like a good bet. Their defense could keep things tight against the Bengals.
  4. Jets -1.5 vs. Steelers
    The Jets, with a 53.5% win probability, are expected to narrowly cover the -1.5 spread against the struggling Steelers. Look for New York’s defense to be the difference-maker.
  5. Dolphins +3.0 vs. Colts
    Miami at +3.0 offers strong value, especially with the Colts’ recent inconsistencies. The Dolphins have a 50% chance to cover the spread, making this one of the week’s best bets.

MORE: Get best bets for every Week 7 matchup

Stay tuned for pivotal wins, close finishes, and some surprising upsets.


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To make sure you get accurate and helpful information, this guide has been edited by Jason Bevilacqua as part of our fact-checking process.
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Written by
Nick Slade
Chief Content Officer

Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers and Stats Insider, and specializes in soccer, NBA and NHL betting.

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