NFL Picks Straight Up: Week 6, 2023

Dimers.com provides weekly NFL picks straight up as part of our NFL Picks coverage.

Week 6 of the NFL season is upon us, and we've used our state-of-the-art predictive analytics model to provide you with straight up NFL picks for all 15 games this week.

Get an edge in NFL pick 'em competitions via our data-driven NFL picks for Week 6 of the 2023 NFL season. These picks are based on over 10,000 simulations of every NFL game.

There are 15 games on the slate for Week 6 of the 2023 NFL season, beginning with the Denver Broncos playing the Kansas City Chiefs on Thursday night and ending with the Dallas Cowboys meeting the Los Angeles Chargers on Monday.

These straight up picks for Week 6 are proudly sponsored by Bet365, which has a tasty Bet $5, Get $150 in Bonus Bets offer for new users.

Simply bet $5 on any of the NFL picks below to earn $150 in bonus bets to use on the rest of the Week 6 NFL slate!

See below for a full list of how likely each team is to win in NFL Week 6.

Straight Up NFL Picks - Week 6

Here are our Week 6 NFL predictions, which show how likely it is that each NFL team will win its game this week.

Denver Broncos vs. Kansas City Chiefs

The Broncos play the Chiefs at GEHA Field at Arrowhead Stadium on Thursday to start Week 6. According to our predictive analytics model, the Chiefs have an 81% chance of winning, while the Broncos have a 19% chance.

Denver Broncos vs. Kansas City Chiefs is at GEHA Field at Arrowhead Stadium on Thursday, October 12 at 8:15pm EDT.

All times stated in this article are in Eastern Daylight Time (EDT).

Baltimore Ravens vs. Tennessee Titans

In this week's game between the Ravens and the Titans, Baltimore is more likely to win. Our prediction model gives the Ravens a 68% chance of winning. On the other hand, there is a 32% chance that the Titans will win.

Baltimore Ravens vs. Tennessee Titans is at Tottenham Hotspur Stadium on Sunday, October 15 at 9:30am.

MORE: Super Bowl Odds

Washington Commanders vs. Atlanta Falcons

We are picking the Falcons to win their game against the Commanders this week, with our famous NFL model projecting a 59% win probability for the home team. The Commanders have a 41% chance of winning at Mercedes-Benz Stadium.

If you're looking to bet on this clash, Bet365 has the Falcons listed as -2.5 favorites, whilst the Commanders' moneyline odds are at +124.

Washington Commanders vs. Atlanta Falcons is at Mercedes-Benz Stadium on Sunday, October 15 at 1:00pm.

San Francisco 49ers vs. Cleveland Browns

According to our predictive analytics model, the 49ers are the team to beat in this game, with their win probability at 72%. The Browns, on the other hand, have a 28% chance of winning.

San Francisco 49ers vs. Cleveland Browns is at Cleveland Browns Stadium on Sunday, October 15 at 1:00pm.

MORE: NFL Best Bets

New Orleans Saints vs. Houston Texans

The Saints have a 57% chance of winning on Sunday afternoon, compared to the Texans' 43% chance of victory. This makes the New Orleans Saints our pick to win at NRG Stadium.

New Orleans Saints vs. Houston Texans is at NRG Stadium on Sunday, October 15 at 1:00pm.

Carolina Panthers vs. Miami Dolphins

The Dolphins are favored to win this game, with our model giving them an 88% chance, while the Panthers enter the weekend with a 12% chance of winning at Hard Rock Stadium.

When it comes to betting on this game, Bet365 has the Panthers' moneyline odds set at +610, with the home team Dolphins listed as -13.5 favorites.

Carolina Panthers vs. Miami Dolphins is at Hard Rock Stadium on Sunday, October 15 at 1:00pm.

Seattle Seahawks vs. Cincinnati Bengals

After 10,000 simulations of Seahawks vs. Bengals this Sunday, our model projects the Bengals as the more likely winners with a probability of 56%. Their opponents the Seahawks have a 44% chance of getting the win on the road.

Seattle Seahawks vs. Cincinnati Bengals is at Paycor Stadium on Seattle, October 15 at 1:00pm.

MORE: NFL Player Props

Indianapolis Colts vs. Jacksonville Jaguars

We are picking the Jaguars in this matchup, with the Jaguars given a 63% chance of winning, while the Colts have a 37% chance of an upset win.

Indianapolis Colts vs. Jacksonville Jaguars is at EverBank Stadium on Sunday, October 15 at 1:00pm.

Minnesota Vikings vs. Chicago Bears

The next game of Week 6 sees the Vikings take on the Bears at Soldier Field.

We are predicting the Vikings to win with projected win chance of 62%, while the Bears are projected to have a win chance of 38%.

As for the Vegas betting odds here, Bet365 has the Bears listed as +3 underdogs, with the Vikings' moneyline odds posted at -152.

Minnesota Vikings vs. Chicago Bears is at Soldier Field on Sunday, October 15 at 1:00pm.

New England Patriots vs. Las Vegas Raiders

The likely winner of this matchup is the Raiders who have a projected win chance of 60% according to DimersBOT. On the other side of this matchup, the Patriots have a projected win probability of 40%.

New England Patriots vs. Las Vegas Raiders is at Allegiant Stadium on Sunday, October 15 at 4:05pm.

MORE: Best NFL Bets Today

Arizona Cardinals vs. Los Angeles Rams

We have run our powerful NFL model over this week’s Cardinals-Rams clash 10,000 times, with the Rams coming out as the team to pick. Of those 10,000 simulations, the Rams won 7,052 times, with the Cardinals winning on 2,948 occasions.

Arizona Cardinals vs. Los Angeles Rams is at SoFi Stadium on Sunday, October 15 at 4:25pm.

Detroit Lions vs. Tampa Bay Buccaneers

Next up is the game between the Lions and Buccaneers, with our model projecting the road team as the more likely victor, with Lions rated as a 66% chance of getting the W. The Buccaneers on the other hand are projected to have a 34% chance of winning.

For those interested in betting on this matchup, Bet365 has the Lions' moneyline odds set at -166 for this road game, whilst the hosting Buccaneers are listed as +3 underdogs.

Detroit Lions vs. Tampa Bay Buccaneers is at Raymond James Stadium on Sunday, October 15 at 4:25pm.

Philadelphia Eagles vs. New York Jets

Our next straight up pick this week is for the Eagles to get the win against the Jets. After running 10,000 simulations of this matchup, the Philadelphia have a win probability of 76%, with the Jets at 24%.

Philadelphia Eagles vs. New York Jets is at MetLife Stadium on Sunday, October 15 at 4:25pm.

New York Giants vs. Buffalo Bills

With a win probability of 90% on Sunday night, our straight up pick for this game is the Bills, while their opponent, the Giants, have a projected win chance of 10%.

New York Giants vs. Buffalo Bills is at Highmark Stadium on Sunday, October 15 at 8:20pm.

MORE: NFL Player Prop Picks for Week 6

Dallas Cowboys vs. Los Angeles Chargers

The team to pick here is the Cowboys who have a 59% chance of winning their matchup against the Chargers this Sunday night.

Looking at the betting odds for this Monday Night Football clash, Bet365 has the Chargers listed as +2 underdogs at home, with the Cowboys' moneyline odds available at -130.

Dallas Cowboys vs. Los Angeles Chargers is at SoFi Stadium on Monday, October 16 at 8:15pm.

NFL Picks This Week Straight Up [Week 6, 2023]

• Chiefs (81% win probability)
• Ravens (68%)
• Falcons (59%)
• 49ers (72%)
• Saints (57%)
• Dolphins (88%)
• Bengals (56%)
• Jaguars (63%)
• Vikings (62%)
• Raiders (60%)
• Rams (71%)
• Lions (66%)
• Eagles (76%)
• Bills (90%)
• Cowboys (59%)

NFL Week 6 Slate and Game Times

• Broncos vs. Chiefs (Thursday, 8:15PM ET)
• Ravens vs. Titans (Sunday, 9:30AM ET)
• Commanders vs. Falcons (Sunday, 1:00PM ET)
• 49ers vs. Browns (Sunday, 1:00PM ET)
• Saints vs. Texans (Sunday, 1:00PM ET)
• Panthers vs. Dolphins (Sunday, 1:00PM ET)
• Seahawks vs. Bengals (Sunday, 1:00PM ET)
• Colts vs. Jaguars (Sunday, 1:00PM ET)
• Vikings vs. Bears (Sunday, 1:00PM ET)
• Patriots vs. Raiders (Sunday, 4:05PM ET)
• Cardinals vs. Rams (Sunday, 4:25PM ET)
• Lions vs. Buccaneers (Sunday, 4:25PM ET)
• Eagles vs. Jets (Sunday, 4:25PM ET)
• Giants vs. Bills (Sunday, 8:20PM ET)
• Cowboys vs. Chargers (Monday, 8:15PM ET)

All times mentioned in this article are in Eastern Daylight Time (EDT).

NFL Week 6 Bye Teams: Who Has a Bye This Week?

• Green Bay Packers
• Pittsburgh Steelers

NFL Straight Up Picks and Predictions - Week 6

The NFL Week 6 picks straight up in this article are correct at the time of publication and are subject to change.

Dimers is the best site for NFL predictions, and our straight up picks are being used by football fans all over the country.

If you choose to use our NFL straight up picks for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Please note that all of the odds and probabilities on this page are subject to change.

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