NFL Picks Straight Up: Week 5, 2023

Week 5 of the NFL season is here, and we've used our powerful predictive analytics model to give you straight up NFL picks for all 14 games.

Gain the edge in NFL pick 'em competitions with our data-driven NFL picks for Week 5 of the 2023 NFL season. These picks are based on over 10,000 simulations of each NFL game.

There are 14 games scheduled for Week 5 of the 2023 NFL season, starting with the Chicago Bears playing the Washington Commanders on Thursday night and ending with the meeting between the Green Bay Packers and the Las Vegas Raiders.

These straight up picks for Week 5 are presented by Bet365, which has an awesome Bet $1, Get $365 in Bonus Bets offer for new users.

Simply bet $1 on any of the NFL picks below to earn $365 in bonus bets to use on the rest of the Week 5 NFL slate!

See below for a full list of each team's chances of winning in NFL Week 5.

Straight Up NFL Picks - Week 5

Listed below are our Week 5 NFL predictions, which show the chances of each NFL team winning its game this week.

Chicago Bears vs. Washington Commanders

The Bears play the Commanders at FedExField on Thursday to start Week 5. According to our model, the Commanders have a 70% chance of winning, while the Bears have a 30% chance.

When looking at player props for the opening game of Week 2, our model projects Justin Fields (QB) as the most likely player from the Bears to score the first TD in the game with a probability of 11.3%, while Brian Robinson (RB) is the most likely from the Commanders at 11.1%.

Chicago Bears vs. Washington Commanders is at FedExField on Thursday, October 5 at 8:15pm EDT.

All times stated in this article are in Eastern Daylight Time (EDT).

Jacksonville Jaguars vs. Buffalo Bills

In this week's game between the Jaguars and the Bills, Buffalo is more likely to win. Our prediction model gives the Bills a 70% chance of winning. On the other hand, there is a 30% chance that the Jaguars will pull off an upset win.

Jacksonville Jaguars vs. Buffalo Bills is at Tottenham Hotspur Stadium on Sunday, October 8 at 9:30am.

MORE: Super Bowl Odds

Tennessee Titans vs. Indianapolis Colts

We are picking the Titans to win their game against the Colts this week, with our famous NFL model projecting a 51% win probability for the road team. The Colts have a 49% chance of winning at Lucas Oil Stadium.

If you're looking to bet on this clash, Bet365 has the Colts listed as -1 favorites, whilst the Titans' moneyline odds are at -102.

Tennessee Titans vs. Indianapolis Colts is at Lucas Oil Stadium on Sunday, October 8 at 1:00pm.

Houston Texans vs. Atlanta Falcons

According to our predictive analytics model, the Falcons are the team to beat in this game, with their win probability at 56%. The Texans, on the other hand, have a 44% chance of winning.

Houston Texans vs. Atlanta Falcons is at Mercedes-Benz Stadium on Sunday, October 8 at 1:00pm.

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Carolina Panthers vs. Detroit Lions

The Lions have a 79% chance of winning on Sunday afternoon, compared to the Panthers' 21% chance of victory. This makes the Detroit Lions our pick to win at Ford Field.

Carolina Panthers vs. Detroit Lions is at Ford Field on Sunday, October 8 at 1:00pm.

Baltimore Ravens vs. Pittsburgh Steelers

The Ravens are favored to win here, with our model giving them a 68% chance, while the Steelers enter the weekend with a 32% chance of securing a win at Acrisure Stadium.

When it comes to betting on this game, Bet365 has the Ravens' moneyline odds set at -188, with the home team Steelers listed as +3.5 underdogs.

Baltimore Ravens vs. Pittsburgh Steelers is at Acrisure Stadium on Sunday, October 8 at 1:00pm.

New Orleans Saints vs. New England Patriots

After 10,000 simulations of Saints vs. Patriots this Sunday, our model projects the Patriots as the more likely winners with a probability of 58%. Their opponents the Saints have a 42% chance of getting the win on the road.

New Orleans Saints vs. New England Patriots is at Gillette Stadium on New Orleans, October 8 at 1:00pm.

MORE: NFL Player Props

New York Giants vs. Miami Dolphins

We are picking the Dolphins who have an 84% chance of winning the matchup, while the Giants have a 16% chance of an upset win.

New York Giants vs. Miami Dolphins is at Hard Rock Stadium on Sunday, October 8 at 1:00pm.

Philadelphia Eagles vs. Los Angeles Rams

The next game of Week 5 sees the Eagles take on the Rams at SoFi Stadium.

We are predicting the Eagles to win with projected win chance of 65%, while the Rams are projected to have a win chance of 35%.

As for the Vegas betting odds here, Bet365 has the Rams listed as +4.5 underdogs, with the Eagles' moneyline odds posted at -215.

Philadelphia Eagles vs. Los Angeles Rams is at SoFi Stadium on Sunday, October 8 at 4:05pm.

Cincinnati Bengals vs. Arizona Cardinals

The likely winner of this matchup is the Bengals who have a projected win chance of 61% according to DimersBOT. On the other side of this matchup, the Cardinals have a projected win probability of 39%.

Cincinnati Bengals vs. Arizona Cardinals is at State Farm Stadium on Sunday, October 8 at 4:05pm.

MORE: Best NFL Bets Today

New York Jets vs. Denver Broncos

We have run our powerful NFL model over this week’s Jets-Broncos clash 10,000 times, with the Broncos coming out as the team to pick. Of those 10,000 simulations, the Broncos won 5,573 times, with the Jets winning on 4,427 occasions.

New York Jets vs. Denver Broncos is at Empower Field at Mile High on Sunday, October 8 at 4:25pm.

Kansas City Chiefs vs. Minnesota Vikings

Next up is the game between the Chiefs and Vikings, with our model projecting the road team as the more likely victor, with Chiefs rated as a 61% chance of getting the W. The Vikings on the other hand are projected to have a 39% chance of winning.

For those interested in betting on this matchup, Bet365 has the Chiefs' moneyline odds set at -220 for this road game, whilst the hosting Vikings are listed as +5.5 underdogs.

Kansas City Chiefs vs. Minnesota Vikings is at U.S. Bank Stadium on Sunday, October 8 at 4:25pm.

Dallas Cowboys vs. San Francisco 49ers

Our next straight up pick this week is for the 49ers to get the win against the Cowboys. After running 10,000 simulations of this matchup, the San Francisco have a win probability of 61%, with the Cowboys at 39%.

Dallas Cowboys vs. San Francisco 49ers is at Levi's Stadium on Sunday, October 8 at 8:20pm.

Green Bay Packers vs. Las Vegas Raiders

With a win probability of 62% on Monday night, our straight up pick for this match is the Packers, while their opponent, the Raiders, have a projected win chance of 38%.

Green Bay Packers vs. Las Vegas Raiders is at Allegiant Stadium on Monday, October 9 at 8:15pm.

MORE: NFL Player Prop Picks for Week 5

NFL Picks This Week Straight Up [Week 5, 2023]

• Commanders (70% win probability)
• Bills (70%)
• Titans (51%)
• Falcons (56%)
• Lions (79%)
• Ravens (68%)
• Patriots (58%)
• Dolphins (84%)
• Eagles (65%)
• Bengals (61%)
• Broncos (56%)
• Chiefs (61%)
• 49ers (61%)
• Packers (62%)

NFL Week 5 Slate and Game Times

• Bears vs. Commanders (Thursday, 8:15PM ET)
• Jaguars vs. Bills (Sunday, 9:30AM ET)
• Titans vs. Colts (Sunday, 1:00PM ET)
• Texans vs. Falcons (Sunday, 1:00PM ET)
• Panthers vs. Lions (Sunday, 1:00PM ET)
• Ravens vs. Steelers (Sunday, 1:00PM ET)
• Saints vs. Patriots (Sunday, 1:00PM ET)
• Giants vs. Dolphins (Sunday, 1:00PM ET)
• Eagles vs. Rams (Sunday, 4:05PM ET)
• Bengals vs. Cardinals (Sunday, 4:05PM ET)
• Jets vs. Broncos (Sunday, 4:25PM ET)
• Chiefs vs. Vikings (Sunday, 4:25PM ET)
• Cowboys vs. 49ers (Sunday, 8:20PM ET)
• Packers vs. Raiders (Monday, 8:15PM ET)

All times mentioned in this article are in Eastern Daylight Time (EDT).

NFL Week 5 Bye Teams: Who Has a Bye This Week?

• Cleveland Browns
• Los Angeles Chargers
• Seattle Seahawks
• Tampa Bay Buccaneers

NFL Straight Up Picks and Predictions - Week 5

The NFL Week 5 picks straight up in this article are correct at the time of publication and are subject to change.

Dimers is the best site for NFL predictions, and our straight up picks are being used by football fans all over the country.

If you choose to use our NFL straight up picks for betting purposes, it's important to gamble responsibly and keep track of your money. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Please note that all of the odds and probabilities on this page are subject to change.

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