NFL Picks Straight Up: Week 3, 2023

Week 3 of the NFL season is here, and we've used our powerful predictive analytics model to provide you with straight up NFL picks for all 16 games.

Here a week late? Check out our NFL Picks Straight Up: Week 4, 2023.

Secure an edge in NFL pick 'em contests with our data-driven NFL picks for Week 3 of the 2023 NFL season. These picks are based on over 10,000 simulations of every NFL game.

There are 16 games scheduled for Week 3 of the 2023 NFL season, beginning with the NY Giants playing the San Francisco 49ers on Thursday night and concluding with the Los Angeles Rams facing the Cincinnati Bengals on Monday night.

These straight up picks for Week 3 are brought to you by Bet365, which has an awesome Bet $1, Get $365 in Bonus Bets promo for new customers.

Simply bet $1 on any of the NFL picks below to earn $365 in bonus bets to use on the rest of the Week 3 NFL slate!

See below for a full breakdown of how likely each team is to win in NFL Week 3.

Straight Up NFL Picks - Week 3

Here are our Week 3 NFL predictions, which show how likely it is that each NFL team will win its game this week.

NY Giants vs. San Francisco 49ers

The Giants face the 49ers at Levi's Stadium on Thursday night to start Week 3. According to our predictive analytics model, the 49ers have an 83% chance of winning, while the Giants have a 17% chance.

NY Giants vs. San Francisco 49ers is at Levi's Stadium on Thursday, September 21 at 8:15pm EDT.

All times mentioned in this article are in Eastern Daylight Time (EDT).

Indianapolis Colts vs. Baltimore Ravens

In this week's game between the Colts and the Ravens, Baltimore is more likely to win. Our prediction model gives the Ravens a 77% chance of winning. On the other hand, there is a 23% chance that the Colts will pull off an upset win.

Indianapolis Colts vs. Baltimore Ravens is at M&T Bank Stadium on Sunday, September 24 at 1:00pm.

MORE: Super Bowl Odds

Denver Broncos vs. Miami Dolphins

We are picking the Dolphins to win their game against the Broncos this week, with our trusted NFL model projecting a 74% win probability for the home team. The Broncos have a 26% chance of winning at Hard Rock Stadium.

If you're looking to bet on this clash, Bet365 has the Dolphins listed as -6.5 favorites, whilst the Broncos' moneyline odds are at +240.

Denver Broncos vs. Miami Dolphins is at Hard Rock Stadium on Sunday, September 24 at 1:00pm.

New England Patriots vs. New York Jets

According to our predictive analytics model, the Patriots are the team to beat in this game, with their win probability at 59%. The Jets, on the other hand, have a 41% chance of winning.

New England Patriots vs. New York Jets is at MetLife Stadium on Sunday, September 24 at 1:00pm.

MORE: NFL Best Bets

Houston Texans vs. Jacksonville Jaguars

The Jaguars have an 83% chance of winning on Sunday afternoon, compared to the Texans' 17% chance of victory. This makes the Jacksonville Jaguars our pick to win at TIAA Bank Field.

Houston Texans vs. Jacksonville Jaguars is at TIAA Bank Field on Sunday, September 24 at 1:00pm.

Tennessee Titans vs. Cleveland Browns

The Browns are favorites to win their Week 3 game, with our predictive analytics model giving them a 63% chance, while the Titans enter the weekend with a 37% chance of locking in a win at Cleveland Browns Stadium.

When it comes to betting on this game, Bet365 has the Titans' moneyline odds set at +150, with the home team Browns listed as -3.5 favorites.

Tennessee Titans vs. Cleveland Browns is at Cleveland Browns Stadium on Sunday, September 24 at 1:00pm.

Atlanta Falcons vs. Detroit Lions

After 10,000 simulations of Falcons vs. Lions this Sunday, our model projects the Lions as the more likely winners with a probability of 58%. Their opponents the Falcons have a 42% chance of getting the win on the road.

Atlanta Falcons vs. Detroit Lions is at Ford Field on Atlanta, September 24 at 1:00pm.

MORE: NFL Player Props

New Orleans Saints vs. Green Bay Packers

DimersBOT is picking the Packers in this game, with the Packers given a 56% chance of winning, while the Saints have a 44% win probability.

New Orleans Saints vs. Green Bay Packers is at Lambeau Field on Sunday, September 24 at 1:00pm.

Buffalo Bills vs. Washington Commanders

The next game of Week 3 sees the Bills take on the Commanders at FedExField.

We are predicting the Bills to win with probability of 67%, while the Commanders are projected to have a win chance of 33%.

As for the Vegas betting odds here, Bet365 has the Commanders listed as +6.5 underdogs, with the Bills' moneyline odds posted at -275.

Buffalo Bills vs. Washington Commanders is at FedExField on Sunday, September 24 at 1:00pm.

Los Angeles Chargers vs. Minnesota Vikings

The likely winner of this matchup is the Chargers who have a projected win chance of 64% according to DimersBOT. On the other side of this matchup, the Vikings have a projected win probability of 36%.

Los Angeles Chargers vs. Minnesota Vikings is at U.S. Bank Stadium on Sunday, September 24 at 1:00pm.

MORE: Best NFL Bets Today

Carolina Panthers vs. Seattle Seahawks

We have run our powerful NFL model over this week’s Panthers-Seahawks clash 10,000 times, with the Seahawks coming out as the team to pick. Of those 10,000 simulations, the Seahawks won 7,135 times, with the Panthers winning on 2,865 occasions.

Carolina Panthers vs. Seattle Seahawks is at Lumen Field on Sunday, September 24 at 4:05pm.

Chicago Bears vs. Kansas City Chiefs

Next up is the game between the Bears and Chiefs, with our model projecting the home team as the more likely victor, with Chiefs rated as a 85% chance of getting the W. The Bears on the other hand are projected to have a 15% chance of winning.

For those interested in betting on this matchup, Bet365 has the Bears' moneyline odds set at +550 for this road game, whilst the hosting Chiefs are listed as -13.5 favorites.

Chicago Bears vs. Kansas City Chiefs is at GEHA Field at Arrowhead Stadium on Sunday, September 24 at 4:25pm.

Dallas Cowboys vs. Arizona Cardinals

Our next straight up pick this week is for the Cowboys to get the win against the Cardinals. After running 10,000 simulations of this matchup, the Dallas have a win probability of 86%, with the Cardinals at 14%.

Dallas Cowboys vs. Arizona Cardinals is at State Farm Stadium on Sunday, September 24 at 4:25pm.

Pittsburgh Steelers vs. Las Vegas Raiders

With a win probability of 57% on Sunday night, our staight up pick for this game is the Steelers, while their opponent, the Raiders, have a projected win chance of 43%.

Pittsburgh Steelers vs. Las Vegas Raiders is at Allegiant Stadium on Sunday, September 24 at 8:20pm.

MORE: NFL Player Prop Picks for Week 3

Philadelphia Eagles vs. Tampa Bay Buccaneers

The team to pick here is the Eagles who have a 71% chance of winning their matchup against the Buccaneers this Sunday night.

Looking at the betting odds for this Monday Night Football clash, Bet365 has the Buccaneers listed as +5.5 underdogs at home, with the Eagles' moneyline odds available at -218.

Philadelphia Eagles vs. Tampa Bay Buccaneers is at Raymond James Stadium on Monday, September 25 at 7:15pm.

Los Angeles Rams vs. Cincinnati Bengals

Our pick to win the final game of Week 3 is Bengals, who have a win probability of 53%. Their opponents are projected to have a 47% chance of getting the W.

Los Angeles Rams vs. Cincinnati Bengals is at Paycor Stadium on Monday, September 25 at 8:15pm.

NFL Picks This Week Straight Up [Week 3, 2023]

• 49ers (83% win probability)
• Ravens (77%)
• Dolphins (74%)
• Patriots (59%)
• Jaguars (83%)
• Browns (63%)
• Lions (58%)
• Packers (56%)
• Bills (67%)
• Chargers (64%)
• Seahawks (71%)
• Chiefs (85%)
• Cowboys (86%)
• Steelers (57%)
• Eagles (71%)
• Bengals (53%)

NFL Week 3 Slate and Game Times

• Giants vs. 49ers (Thursday, 8:15PM ET)
• Colts vs. Ravens (Sunday, 1:00PM ET)
• Broncos vs. Dolphins (Sunday, 1:00PM ET)
• Patriots vs. Jets (Sunday, 1:00PM ET)
• Texans vs. Jaguars (Sunday, 1:00PM ET)
• Titans vs. Browns (Sunday, 1:00PM ET)
• Falcons vs. Lions (Sunday, 1:00PM ET)
• Saints vs. Packers (Sunday, 1:00PM ET)
• Bills vs. Commanders (Sunday, 1:00PM ET)
• Chargers vs. Vikings (Sunday, 1:00PM ET)
• Panthers vs. Seahawks (Sunday, 4:05PM ET)
• Bears vs. Chiefs (Sunday, 4:25PM ET)
• Cowboys vs. Cardinals (Sunday, 4:25PM ET)
• Steelers vs. Raiders (Sunday, 8:20PM ET)
• Eagles vs. Buccaneers (Monday, 7:15PM ET)
• Rams vs. Bengals (Monday, 8:15PM ET)

All times mentioned in this article are in Eastern Daylight Time (EDT).

NFL Week 3 Bye Teams: Who Has a Bye This Week?

All 32 teams are scheduled to play in Week 3 of the 2023 NFL season, which means no team has a bye this week.

NFL Straight Up Picks and Predictions - Week 3

The NFL Week 3 picks straight up in this article are correct at the time of publication and are subject to change.

Dimers is the best site for NFL predictions, and our straight up picks are being used by football fans all over the country.

If you decide to use our NFL straight up picks for betting purposes, it's important to gamble responsibly and manage your finances effectively. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Please note that all of the odds and probabilities on this page are subject to change.

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