NFL Picks and Predictions Straight Up: Week 5, 2024

At Dimers.com, we offer NFL picks straight up for Week 5 and every week, as part of our in-depth NFL picks and NFL predictions coverage.

With Week 5 of the NFL season upon us, we've harnessed our dynamic predictive analytics model to deliver NFL straight up picks for all 14 games this week.

Gain the edge in your NFL pick 'em contests via our data-driven NFL Week 5 picks straight up, powered by thousands of game simulations.

Week 5 of the NFL season features 14 games, beginning with the Tampa Bay Buccaneers facing the Atlanta Falcons on Thursday night and ending with the New Orleans Saints taking on the Kansas City Chiefs on Monday.

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For more NFL betting coverage, check out the best NFL week 5 odds and our NFL picks against the spread for Week 5.

NFL Picks This Week Straight Up: Week 5, 2024

Here are our Week 5 NFL picks, highlighting each team's chances of winning their game this week.

Tampa Bay Buccaneers vs. Atlanta Falcons

The Buccaneers kick off Week 5 against the Falcons at Mercedes-Benz Stadium on Thursday night. According to our model, the Falcons have a 53% chance of winning, while the Buccaneers have a 47% chance.

For Week 5's opening game, our model highlights NFL player props with Mike Evans (WR) as the most likely player from the Buccaneers to score the first TD at 10.3%, while Bijan Robinson (RB) is the top candidate from the Falcons at 13.5%.

The Tampa Bay Buccaneers vs. Atlanta Falcons game at Mercedes-Benz Stadium is scheduled for Thursday, October 3 at 8:15pm. All times mentioned in this article are in Eastern Standard Time (EST).

New York Jets vs. Minnesota Vikings

For this week's game between the Jets and the Vikings, Minnesota is more likely to win. Our prediction model gives the Vikings a 61% chance of winning. On the other hand, there is a 39% chance that the Jets will win.

The New York Jets vs. Minnesota Vikings matchup at Tottenham Hotspur Stadium will take place on Sunday, October 6 at 9:30am.

As the first week of byes hit, track the top teams with our updated NFL futures, highlighting top Super Bowl contenders.

Cleveland Browns vs. Washington Commanders

We are picking the Commanders to win their game against the Browns this week, with our famous NFL model projecting a 65% win probability for the home team. The Browns have a 35% chance of winning at Northwest Stadium.

For betting purposes, the Commanders are listed as -3.5 favorites, with the Browns' moneyline at +145.

The Cleveland Browns vs. Washington Commanders game at Northwest Stadium is slated for Sunday, October 6 at 1:00pm.

Baltimore Ravens vs. Cincinnati Bengals

According to our predictive analytics model, the Ravens are the team to beat in this game, with their win probability at 57%. The Bengals, on the other hand, have a 43% chance of winning.

The Baltimore Ravens vs. Cincinnati Bengals game at Paycor Stadium is set for Sunday, October 6 at 1:00pm.

Buffalo Bills vs. Houston Texans

The Bills have a 53% chance of winning on Sunday afternoon, compared to the Texans' 47% chance of victory. This makes the Buffalo Bills our pick to win at NRG Stadium.

The Buffalo Bills vs. Houston Texans matchup at NRG Stadium is scheduled for Sunday, October 6 at 1:00pm.

Indianapolis Colts vs. Jacksonville Jaguars

The Jaguars are favorites to win this game, with our predictive analytics model giving them a 58% chance, while the Colts enter the weekend with a 42% chance of locking in a win at EverBank Stadium.

When it comes to betting on this game, the Colts' moneyline odds are set at +128, with the home team Jaguars listed as -2.5 favorites.

The Indianapolis Colts vs. Jacksonville Jaguars game at EverBank Stadium will take place on Sunday, October 6 at 1:00pm.

Carolina Panthers vs. Chicago Bears

After 10,000 simulations of Panthers vs. Bears this Sunday, our model projects the Bears as the more likely winners with a probability of 65%. Their opponents, the Panthers, have a 35% chance of getting the win on the road.

The Carolina Panthers vs. Chicago Bears matchup at Soldier Field is slated for Sunday, October 6 at 1:00pm.

Miami Dolphins vs. New England Patriots

We are picking the Patriots, who have a 53% chance of winning the matchup, while the Dolphins have a 47% win probability.

The Miami Dolphins vs. New England Patriots game at Gillette Stadium will take place on Sunday, October 6 at 1:00pm.

Arizona Cardinals vs. San Francisco 49ers

The next game of Week 5 sees the Cardinals take on the 49ers at Levi's Stadium.

We predict the 49ers to win with a probability of 72%, while the Cardinals are projected to have a win chance of 28%.

As for the Vegas betting odds here, the 49ers are listed as -7.5 favorites, with the Cardinals' moneyline odds posted at +290.

The Arizona Cardinals vs. San Francisco 49ers game at Levi's Stadium is scheduled for Sunday, October 6 at 4:05pm.

Las Vegas Raiders vs. Denver Broncos

The likely winner of this matchup is the Broncos, who have a projected win chance of 60%, according to DimersBOT. On the other side of this matchup, the Raiders have a projected win probability of 40%.

The Las Vegas Raiders vs. Denver Broncos matchup at Empower Field at Mile High is set for Sunday, October 6 at 4:05pm.

Green Bay Packers vs. Los Angeles Rams

We have run our powerful NFL model over this week’s Packers-Rams clash 10,000 times, with the Packers coming out as the team to pick. Of those 10,000 simulations, the Packers won 6,092 times, with the Rams winning on 3,908 occasions.

The Green Bay Packers vs. Los Angeles Rams game at SoFi Stadium is scheduled for Sunday, October 6 at 4:25pm.

New York Giants vs. Seattle Seahawks

Next up is the game between the Giants and Seahawks, with our model projecting the home team as the more likely victor, with the Seahawks rated as having a 73% chance of getting the W. The Giants, on the other hand, are projected to have a 27% chance of winning.

For those interested in betting on this matchup, the oddsmakers have the Giants' moneyline odds set at +230 for this road game, while the hosting Seahawks are listed as -6 favorites.

The New York Giants vs. Seattle Seahawks game at Lumen Field will take place on Sunday, October 6 at 4:25pm.

Dallas Cowboys vs. Pittsburgh Steelers

Our next straight up pick this week is for the Steelers to get the win against the Cowboys. After running 10,000 simulations of this matchup, the Pittsburgh have a win probability of 58%, with the Cowboys at 42%.

The Dallas Cowboys vs. Pittsburgh Steelers game at Acrisure Stadium is slated for Sunday, October 6 at 8:20pm.

New Orleans Saints vs. Kansas City Chiefs

With a win probability of 68% on Monday night, our straight up pick for this game is the Chiefs, while their opponent, the Saints, have a projected win chance of 32%.

The New Orleans Saints vs. Kansas City Chiefs game at GEHA Field at Arrowhead Stadium will take place on Monday, October 7 at 8:15pm.

For a different angle on this week's NFL action, explore our NFL trends to spot the latest player prop trends.

NFL Week 5 Picks Straight Up:

• Falcons (53% win probability)
• Vikings (61%)
• Commanders (65%)
• Ravens (57%)
• Bills (53%)
• Jaguars (58%)
• Bears (65%)
• Patriots (53%)
• 49ers (72%)
• Broncos (60%)
• Packers (61%)
• Seahawks (73%)
• Steelers (58%)
• Chiefs (68%)

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NFL Straight Up Picks and Predictions for Week 5

The NFL Week 5 predictions straight up in this article are accurate at the time of publication but may change.

Dimers.com is the best site for NFL predictions, with our straight up picks trusted by football fans across the country.

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