NFL Picks and Predictions Straight Up: Week 15, 2024

At Dimers.com, we provide NFL picks straight up for Week 15 and every week, as part of our detailed NFL picks and NFL predictions coverage.

With Week 15 of the NFL season here, we've leveraged our powerful predictive analytics model to deliver a list of NFL straight up picks for all 16 games this week.

Gain the edge in your NFL pick 'em contests with our data-driven NFL Week 15 picks straight up, powered by thousands of game simulations.

Week 15 of the NFL season features 16 games, starting with the Los Angeles Rams facing the San Francisco 49ers on Thursday night and wrapping up with the Atlanta Falcons taking on the Las Vegas Raiders on Monday night.

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For more NFL betting coverage, check out the best NFL week 15 odds and our NFL picks against the spread for Week 15.

NFL Picks This Week Straight Up: Week 15, 2024

Here are our Week 15 NFL picks, highlighting each team's chances of winning their game this week.

Los Angeles Rams vs. San Francisco 49ers

The Rams kick off Week 15 against the 49ers at Levi's Stadium on Thursday night. According to our predictive analytics model, the 49ers have a 59% chance of winning, while the Rams have a 41% chance.

For Week 15's opening game, our model highlights NFL player props with Kyren Williams (RB) as the most likely player from the Rams to score the first TD at 12.1%, while Isaac Guerendo (RB) is the top candidate from the 49ers at 10.0%.

The Los Angeles Rams vs. San Francisco 49ers game at Levi's Stadium is scheduled for Thursday, December 12 at 8:15pm. All times stated in this article are in Eastern Standard Time (EST).

Baltimore Ravens vs. New York Giants

For this week's game between the Ravens and the Giants, Baltimore is more likely to win. Our prediction model gives the Ravens a 93% chance of winning. On the other hand, there is a 7% chance that the Giants will secure an unlikely victory.

The Baltimore Ravens vs. New York Giants matchup at MetLife Stadium will take place on Sunday, December 15 at 1:00pm.

As the playoffs apporoach, track the top teams with Dimers' updated NFL futures, highlighting top Super Bowl contenders.

New York Jets vs. Jacksonville Jaguars

We are picking the Jets to win their game against the Jaguars this week, with our famous NFL model projecting a 64% win probability for the road team. The Jaguars have a 36% chance of winning at EverBank Stadium.

For betting purposes, the Jaguars are listed as +3.5 underdogs, with the Jets' moneyline at -166.

The New York Jets vs. Jacksonville Jaguars game at EverBank Stadium is slated for Sunday, December 15 at 1:00pm.

Washington Commanders vs. New Orleans Saints

According to our predictive analytics model, the Commanders are the team to beat in this game, with their win probability at 76%. The Saints, on the other hand, have a 24% chance of winning.

The Washington Commanders vs. New Orleans Saints game at Caesars Superdome is set for Sunday, December 15 at 1:00pm.

Cincinnati Bengals vs. Tennessee Titans

The Bengals have a 68% chance of winning on Sunday afternoon, compared to the Titans' 32% chance of victory. This makes the Cincinnati Bengals our pick to win at Nissan Stadium.

The Cincinnati Bengals vs. Tennessee Titans matchup at Nissan Stadium is scheduled for Sunday, December 15 at 1:00pm.

Miami Dolphins vs. Houston Texans

The Texans are favorites to win this game, with our predictive analytics model giving them a 58% chance, while the Dolphins enter the weekend with a 42% chance of winning at NRG Stadium.

When it comes to betting on this game, the Dolphins' moneyline odds are set at +130, with the home team Texans listed as -3 favorites.

The Miami Dolphins vs. Houston Texans game at NRG Stadium will take place on Sunday, December 15 at 1:00pm.

Kansas City Chiefs vs. Cleveland Browns

After 10,000 simulations of Chiefs vs. Browns this Sunday, our model projects the Chiefs as the more likely winners with a probability of 64%. Their opponents, the Browns, have a 36% chance of getting the win at home.

The Kansas City Chiefs vs. Cleveland Browns matchup at Huntington Bank Field is slated for Sunday, December 15 at 1:00pm.

Dallas Cowboys vs. Carolina Panthers

We are picking the Panthers, who have a 59% chance of winning the game, while the Cowboys have a 41% win probability.

The Dallas Cowboys vs. Carolina Panthers game at Bank of America Stadium will take place on Sunday, December 15 at 1:00pm.

New England Patriots vs. Arizona Cardinals

The next game of Week 15 sees the Patriots take on the Cardinals at State Farm Stadium.

We predict the Cardinals to win with a probability of 69%, while the Patriots are projected to have a win chance of 31%.

As for the Vegas betting odds here, the Cardinals are listed as -6.5 favorites, with the Patriots' moneyline odds posted at +215.

The New England Patriots vs. Arizona Cardinals game at State Farm Stadium is scheduled for Sunday, December 15 at 4:25pm.

Tampa Bay Buccaneers vs. Los Angeles Chargers

The likely winner of this matchup is the Chargers, who have a projected win chance of 58%, according to DimersBOT. On the other side of this matchup, the Buccaneers have a projected win probability of 42%.

The Tampa Bay Buccaneers vs. Los Angeles Chargers matchup at SoFi Stadium is set for Sunday, December 15 at 4:25pm.

Buffalo Bills vs. Detroit Lions

We have run our powerful NFL model over this week’s Bills-Lions clash 10,000 times, with the Lions coming out as the team to pick. Of those 10,000 simulations, the Lions won 5,956 times, with the Bills winning on 4,044 occasions.

The Buffalo Bills vs. Detroit Lions game at Ford Field is scheduled for Sunday, December 15 at 4:25pm.

Indianapolis Colts vs. Denver Broncos

Next up is the game between the Colts and Broncos, with our model projecting the home team as the more likely victor, with the Broncos rated as having a 68% chance of getting the W. The Colts, on the other hand, are projected to have a 32% chance of winning.

For those interested in betting on this matchup, the oddsmakers have the Colts' moneyline odds set at +176 for this road game, while the hosting Broncos are listed as -4 favorites.

The Indianapolis Colts vs. Denver Broncos game at Empower Field at Mile High will take place on Sunday, December 15 at 4:25pm.

Pittsburgh Steelers vs. Philadelphia Eagles

Our next straight up pick this week is for the Eagles to get the win against the Steelers. After running 10,000 simulations of this matchup, the Philadelphia have a win probability of 71%, with the Steelers at 29%.

The Pittsburgh Steelers vs. Philadelphia Eagles game at Lincoln Financial Field is slated for Sunday, December 15 at 4:25pm.

Green Bay Packers vs. Seattle Seahawks

With a win probability of 57% on Sunday night, our straight up pick for this matchup is the Packers, while their opponent, the Seahawks, have a projected win chance of 43%.

The Green Bay Packers vs. Seattle Seahawks game at Lumen Field will take place on Sunday, December 15 at 8:20pm.

For a different angle on this week's NFL action, explore Dimers' NFL trends to find the latest player prop trends.

Chicago Bears vs. Minnesota Vikings

The team to pick here is the Vikings, who have a 74% chance of winning their matchup against the Bears this Sunday night.

Looking at the betting odds for this Monday Night Football clash, the Vikings are listed as -7 favorites at home, with the Bears' moneyline odds available at +260.

The Chicago Bears vs. Minnesota Vikings game at U.S. Bank Stadium is scheduled for Monday, December 16 at 8:00pm.

Atlanta Falcons vs. Las Vegas Raiders

Our pick to win the final game of Week 15 is the Falcons, who have a win probability of 64%. Their opponents are projected to have a 36% chance of getting the W.

The Atlanta Falcons vs. Las Vegas Raiders game at Allegiant Stadium is set for Monday, December 16 at 8:30pm.

Full List of NFL Week 15 Picks Straight Up:

• 49ers (59% win probability)
• Ravens (93%)
• Jets (64%)
• Commanders (76%)
• Bengals (68%)
• Texans (58%)
• Chiefs (64%)
• Panthers (59%)
• Cardinals (69%)
• Chargers (58%)
• Lions (60%)
• Broncos (68%)
• Eagles (71%)
• Packers (57%)
• Vikings (74%)
• Falcons (64%)

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NFL Straight Up Picks and Predictions for Week 15

The NFL Week 15 predictions straight up in this article are accurate at the time of publication but may change.

Dimers.com is the best site for NFL predictions, with our straight up picks trusted by football fans across the country.

If you choose to use our NFL straight up picks for betting, it's crucial to gamble responsibly and keep track of your money. For more resources and advice on responsible gambling, please call 1-800-GAMBLER.

Please note that all NFL odds and probabilities mentioned on this page are subject to change.

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