NFL Picks and Predictions Straight Up: Week 12, 2024

At Dimers.com, we offer NFL picks straight up for Week 12 and beyond, as part of our detailed NFL picks and NFL predictions coverage.

With Week 12 of the NFL season here, we've used our dynamic predictive analytics model to deliver a list of NFL straight up picks for all 13 games this week.

Gain the edge in your NFL pick 'em contests by following our data-driven NFL Week 12 picks straight up, powered by thousands of game simulations.

Week 12 of the NFL season features 13 games, starting with the Pittsburgh Steelers facing the Cleveland Browns on Thursday night and wrapping up with the Baltimore Ravens taking on the Los Angeles Chargers on Sunday.

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For more NFL betting coverage, check out the best NFL week 12 odds for a breakdown on the moneyline, spread and total for every game this week.

NFL Picks This Week Straight Up: Week 12, 2024

Listed below are our Week 12 NFL picks, highlighting each team's chances of winning their game this week.

Pittsburgh Steelers vs. Cleveland Browns

The Steelers kick off Week 12 against the Browns at Huntington Bank Field on Thursday night. According to our predictive analytics model, the Steelers have a 65% chance of winning, while the Browns have a 35% chance.

For Week 12's opening game, our model highlights NFL player props with Najee Harris (RB) as the most likely player from the Steelers to score the first TD at 10.4%, while Nick Chubb (RB) is the top candidate from the Browns at 10.6%.

The Pittsburgh Steelers vs. Cleveland Browns game at Huntington Bank Field is scheduled for Thursday, November 21 at 8:15pm. All times stated in this article are in Eastern Standard Time (EST).

Tampa Bay Buccaneers vs. New York Giants

For this week's game between the Buccaneers and the Giants, Tampa Bay is more likely to win. Our prediction model gives the Buccaneers a 71% chance of winning. On the other hand, there is a 29% chance that the Giants will pull off an upset win.

The Tampa Bay Buccaneers vs. New York Giants matchup at MetLife Stadium will take place on Sunday, November 24 at 1:00pm.

As the regular season approaches its conclusion, track the top teams with Dimers' updated NFL futures, highlighting top Super Bowl contenders.

Detroit Lions vs. Indianapolis Colts

We are picking the Lions to win their game against the Colts this week, with our powerful NFL model projecting a 73% win probability for the road team. The Colts have a 27% chance of winning at Lucas Oil Stadium.

For betting purposes, the Colts are listed as +7.5 underdogs, with the Lions' moneyline at -340.

The Detroit Lions vs. Indianapolis Colts game at Lucas Oil Stadium is slated for Sunday, November 24 at 1:00pm.

Tennessee Titans vs. Houston Texans

According to our predictive analytics model, the Texans are the team to beat in this game, with their win probability at 78%. The Titans, on the other hand, have a 22% chance of winning.

The Tennessee Titans vs. Houston Texans game at NRG Stadium is set for Sunday, November 24 at 1:00pm.

New England Patriots vs. Miami Dolphins

The Dolphins have a 73% chance of winning on Sunday afternoon, compared to the Patriots' 27% chance of victory. This makes the Miami Dolphins our pick to win at Hard Rock Stadium.

The New England Patriots vs. Miami Dolphins matchup at Hard Rock Stadium is scheduled for Sunday, November 24 at 1:00pm.

Dallas Cowboys vs. Washington Commanders

The Commanders are favored to win their game this week, with our predictive analytics model giving them an 83% chance, while the Cowboys enter the weekend with a 17% chance of causing an upset at Northwest Stadium.

When it comes to betting on this game, the Cowboys' moneyline odds are set at +440, with the home team Commanders listed as -10.5 favorites.

The Dallas Cowboys vs. Washington Commanders game at Northwest Stadium will take place on Sunday, November 24 at 1:00pm.

Minnesota Vikings vs. Chicago Bears

After 10,000 simulations of Vikings vs. Bears this Sunday, our model projects the Vikings as the more likely winners with a probability of 64%. Their opponents, the Bears, have a 36% chance of getting the win at home.

The Minnesota Vikings vs. Chicago Bears matchup at Soldier Field is slated for Sunday, November 24 at 1:00pm.

Kansas City Chiefs vs. Carolina Panthers

We are picking the Chiefs, who have an 86% chance of winning the matchup, while the Panthers have a 14% win probability.

The Kansas City Chiefs vs. Carolina Panthers game at Bank of America Stadium will take place on Sunday, November 24 at 1:00pm.

Denver Broncos vs. Las Vegas Raiders

The next game of Week 12 sees the Broncos take on the Raiders at Allegiant Stadium.

We predict the Broncos to win with a probability of 71%, while the Raiders are projected to have a win chance of 29%.

As for the Vegas betting odds here, the Raiders are listed as +5.5 underdogs, with the Broncos' moneyline odds posted at -238.

The Denver Broncos vs. Las Vegas Raiders game at Allegiant Stadium is scheduled for Sunday, November 24 at 4:05pm.

Arizona Cardinals vs. Seattle Seahawks

The likely winner of this matchup is the Seahawks, who have a projected win chance of 53%, according to DimersBOT. On the other side of this matchup, the Cardinals have a projected win probability of 47%.

The Arizona Cardinals vs. Seattle Seahawks matchup at Lumen Field is set for Sunday, November 24 at 4:25pm.

San Francisco 49ers vs. Green Bay Packers

We have run our powerful NFL model over this week’s 49ers-Packers clash 10,000 times, with the Packers coming out as the team to pick. Of those 10,000 simulations, the Packers won 5,905 times, with the 49ers winning on 4,095 occasions.

The San Francisco 49ers vs. Green Bay Packers game at Lambeau Field is scheduled for Sunday, November 24 at 4:25pm.

Philadelphia Eagles vs. Los Angeles Rams

Next up is the game between the Eagles and Rams, with our model projecting the road team as the more likely victor, with the Eagles rated as having a 57% chance of getting the W. The Rams, on the other hand, are projected to have a 43% chance of winning.

For those interested in betting on this matchup, the oddsmakers have the Eagles' moneyline odds set at -148 for this road game, while the hosting Rams are listed as +2.5 underdogs.

The Philadelphia Eagles vs. Los Angeles Rams game at SoFi Stadium will take place on Sunday, November 24 at 8:20pm.

Baltimore Ravens vs. Los Angeles Chargers

Our next straight up pick this week is for the Ravens to get the win against the Chargers. After running 10,000 simulations of this matchup, the Baltimore have a win probability of 60%, with the Chargers at 40%.

The Baltimore Ravens vs. Los Angeles Chargers game at SoFi Stadium is slated for Monday, November 25 at 8:15pm.

Full List of NFL Week 12 Picks Straight Up:

• Steelers (65% win probability)
• Buccaneers (71%)
• Lions (73%)
• Texans (78%)
• Dolphins (73%)
• Commanders (83%)
• Vikings (64%)
• Chiefs (86%)
• Broncos (71%)
• Seahawks (53%)
• Packers (59%)
• Eagles (57%)
• Ravens (60%)

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NFL Straight Up Picks and Predictions for Week 12

The NFL Week 12 predictions straight up in this article are accurate at the time of publication but may change.

Dimers.com is the best site for NFL predictions, with our straight up picks trusted by football fans across the country.

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Please note that all NFL odds and probabilities mentioned on this page are subject to change.

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