NFL Picks and Predictions Straight Up: Week 1, 2024

At Dimers.com, we offer NFL picks straight up for Week 1 and beyond, as part of our extensive NFL picks and NFL predictions coverage.

With Week 1 of the NFL season upon us, we've used our sophisticated predictive analytics model to deliver NFL straight up picks for all 16 games this week.

Gain the edge in your NFL pick 'em contests via our data-driven NFL Week 1 picks straight up, powered by thousands of game simulations.

Week 1 of the NFL season features 16 games, beginning with the Baltimore Ravens facing the Kansas City Chiefs on Thursday night and wrapping up with the New York Jets taking on the San Francisco 49ers on Monday night.

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For more NFL betting coverage, check out the best NFL week 1 odds and our NFL picks against the spread for Week 1.

NFL Picks This Week Straight Up: Week 1, 2024

Here are our Week 1 NFL picks, highlighting how likely each team is to win their game this week.

Baltimore Ravens vs. Kansas City Chiefs

The Ravens kick off Week 1 against the Chiefs at GEHA Field at Arrowhead Stadium on Thursday. According to our NFL model, the Chiefs have a 59% chance of winning, while the Ravens have a 41% chance.

For Week 1's opening game, our model highlights NFL player props with Derrick Henry (RB) as the most likely player from the Ravens to score the first TD at 13.0%, while Isiah Pacheco (RB) is the top candidate from the Chiefs at 11.4%.

The Baltimore Ravens vs. Kansas City Chiefs game at GEHA Field at Arrowhead Stadium is scheduled for Thursday, September 5 at 8:20pm. All times mentioned in this article are in Eastern Standard Time (EST).

Green Bay Packers vs. Philadelphia Eagles

For this year's NFL Brazil game between the Packers and the Eagles, Philadelphia is more likely to win. Our prediction model gives the Eagles a 55% chance of winning. On the other hand, there is a 45% chance that the Packers will win.

The Green Bay Packers vs. Philadelphia Eagles matchup at Corinthians Arena in Brazil will take place on Friday, September 6 at 8:15pm.

As the season begins, track the top teams with our updated NFL futures, highlighting top Super Bowl contenders.

Carolina Panthers vs. New Orleans Saints

We are picking the Saints to win their game against the Panthers this week, with our famous NFL model projecting a 64% win probability for the home team. The Panthers have a 36% chance of winning at Caesars Superdome.

For betting purposes, the Saints are listed as -4 favorites, with the Panthers' moneyline at +168.

The Carolina Panthers vs. New Orleans Saints game at Caesars Superdome is slated for Sunday, September 8 at 1:00pm.

Tennessee Titans vs. Chicago Bears

According to our predictive analytics model, the Bears are the team to beat in this game, with their win probability at 61%. The Titans, on the other hand, have a 39% chance of winning.

The Tennessee Titans vs. Chicago Bears game at Soldier Field is set for Sunday, September 8 at 1:00pm.

Houston Texans vs. Indianapolis Colts

The Texans have a 60% chance of winning on Sunday afternoon, compared to the Colts' 40% chance of victory. This makes the Houston Texans our pick to win at Lucas Oil Stadium.

The Houston Texans vs. Indianapolis Colts matchup at Lucas Oil Stadium is scheduled for Sunday, September 8 at 1:00pm.

Arizona Cardinals vs. Buffalo Bills

The Bills are favored to win their game this week, with our model giving them a 71% chance, while the Cardinals enter the weekend with a 29% chance of winning at Highmark Stadium.

When it comes to betting on this game, the Cardinals' moneyline odds are set at +240, with the home team Bills listed as -6.5 favorites.

The Arizona Cardinals vs. Buffalo Bills game at Highmark Stadium will take place on Sunday, September 8 at 1:00pm.

New England Patriots vs. Cincinnati Bengals

After 10,000 simulations of Patriots vs. Bengals this Sunday, our model projects the Bengals as the more likely winners with a probability of 79%. Their opponents, the Patriots, have a 21% chance of getting the win on the road.

The New England Patriots vs. Cincinnati Bengals matchup at Paycor Stadium is slated for Sunday, September 8 at 1:00pm.

Jacksonville Jaguars vs. Miami Dolphins

We are picking the Dolphins, who have a 60% chance of winning the matchup, while the Jaguars have a 40% win probability.

The Jacksonville Jaguars vs. Miami Dolphins game at Hard Rock Stadium will take place on Sunday, September 8 at 1:00pm.

Minnesota Vikings vs. New York Giants

The next game of Week 1 sees the Vikings take on the Giants at MetLife Stadium.

We predict the Vikings to win with a probability of 58%, while the Giants are projected to have a win chance of 42%.

As for the Vegas betting odds here, the Giants are listed as +1.5 underdogs, with the Vikings' moneyline odds posted at -120.

The Minnesota Vikings vs. New York Giants game at MetLife Stadium is scheduled for Sunday, September 8 at 1:00pm.

Pittsburgh Steelers vs. Atlanta Falcons

The likely winner of this matchup is the Falcons, who have a projected win chance of 62%, according to DimersBOT. On the other side of this matchup, the Steelers have a projected win probability of 38%.

The Pittsburgh Steelers vs. Atlanta Falcons matchup at Mercedes-Benz Stadium is set for Sunday, September 8 at 1:00pm.

Denver Broncos vs. Seattle Seahawks

We have run our powerful NFL model over this week’s Broncos-Seahawks clash 10,000 times, with the Seahawks coming out as the team to pick. Of those 10,000 simulations, the Seahawks won 7,150 times, with the Broncos winning on 2,850 occasions.

The Denver Broncos vs. Seattle Seahawks game at Lumen Field is scheduled for Sunday, September 8 at 4:05pm.

Las Vegas Raiders vs. Los Angeles Chargers

Next up is the game between the Raiders and Chargers, with our model projecting the home team as the more likely victor, with the Chargers rated as having a 59% chance of getting the W. The Raiders, on the other hand, are projected to have a 41% chance of winning.

For those interested in betting on this matchup, the oddsmakers have the Raiders' moneyline odds set at +142 for this road game, while the hosting Chargers are listed as -3 favorites.

The Las Vegas Raiders vs. Los Angeles Chargers game at SoFi Stadium will take place on Sunday, September 8 at 4:05pm.

Dallas Cowboys vs. Cleveland Browns

Our next straight up pick this week is for the Browns to get the win against the Cowboys. After running 10,000 simulations of this matchup, the Cleveland have a win probability of 59%, with the Cowboys at 41%.

The Dallas Cowboys vs. Cleveland Browns game at Huntington Bank Field is slated for Sunday, September 8 at 4:25pm.

Washington Commanders vs. Tampa Bay Buccaneers

With a win probability of 61% on Sunday afternoon, our straight up pick for this game is the Buccaneers, while their opponent, the Commanders, have a projected win chance of 39%.

The Washington Commanders vs. Tampa Bay Buccaneers game at Raymond James Stadium will take place on Sunday, September 8 at 4:25pm.

For a different angle on this week's NFL action, explore our NFL trends to spot the latest player prop trends.

Los Angeles Rams vs. Detroit Lions

The team to pick here is the Lions, who have a 61% chance of winning their matchup against the Rams this Sunday night.

Looking at the betting odds for this Sunday Night Football clash, the Lions are listed as -3.5 favorites at home, with the Rams' moneyline odds available at +166.

The Los Angeles Rams vs. Detroit Lions game at Ford Field is scheduled for Sunday, September 8 at 8:20pm.

New York Jets vs. San Francisco 49ers

Our pick to win the final game of Week 1 is the 49ers, who have a win probability of 66%. Their opponents are projected to have a 34% chance of getting the W.

The New York Jets vs. San Francisco 49ers game at Levi's Stadium is set for Monday, September 9 at 8:15pm.

NFL Week 1 Picks Straight Up:

• Chiefs (59% win probability)
• Eagles (55%)
• Saints (64%)
• Bears (61%)
• Texans (60%)
• Bills (71%)
• Bengals (79%)
• Dolphins (60%)
• Vikings (58%)
• Falcons (62%)
• Seahawks (71%)
• Chargers (59%)
• Browns (59%)
• Buccaneers (61%)
• Lions (61%)
• 49ers (66%)

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NFL Week 1 Slate and Game Times:

• Ravens vs. Chiefs (Thursday, 8:20PM ET)
• Packers vs. Eagles (Friday, 8:15PM ET)
• Panthers vs. Saints (Sunday, 1:00PM ET)
• Titans vs. Bears (Sunday, 1:00PM ET)
• Texans vs. Colts (Sunday, 1:00PM ET)
• Cardinals vs. Bills (Sunday, 1:00PM ET)
• Patriots vs. Bengals (Sunday, 1:00PM ET)
• Jaguars vs. Dolphins (Sunday, 1:00PM ET)
• Vikings vs. Giants (Sunday, 1:00PM ET)
• Steelers vs. Falcons (Sunday, 1:00PM ET)
• Broncos vs. Seahawks (Sunday, 4:05PM ET)
• Raiders vs. Chargers (Sunday, 4:05PM ET)
• Cowboys vs. Browns (Sunday, 4:25PM ET)
• Commanders vs. Buccaneers (Sunday, 4:25PM ET)
• Rams vs. Lions (Sunday, 8:20PM ET)
• Jets vs. 49ers (Monday, 8:15PM ET)

NFL Straight Up Picks and Predictions for Week 1

The NFL Week 1 predictions straight up in this article are accurate at the time of publication but may change.

Dimers.com is the best site for NFL predictions, with our straight up picks trusted by football fans across the country.

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Please note that all NFL odds and probabilities mentioned on this page are subject to change.

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