NFL Picks Against the Spread for Week 15, 2024

As part of our extensive NFL betting coverage, Dimers.com provides a weekly list of NFL picks against the spread, and for Week 15, we've harnessed our advanced predictive analytics model to deliver NFL spread picks for all 16 games.

With professional NFL picks against spread for every game on the Week 15 NFL slate, our expert predictive model is here to guide you through another huge week of football.

Below, you'll find a detailed breakdown of each team's chances of covering the spread in Week 15 of the NFL, based on thousands of simulations of each game. These NFL predictions for Week 15 show the probability of each team covering the spread in their respective games.

While the picks in this article are based purely on probabilities, it's crucial for bettors to note that the best betting value may come from better odds available elsewhere.

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For more NFL betting coverage, check out the best NFL week 15 odds and our NFL Week 15 straight up picks.

NFL Spread Picks: Week 15, 2024

Los Angeles Rams vs. San Francisco 49ers (-2.5)

The opening game of Week 15 features the 49ers hosting the Rams, with San Francisco listed as a 2.5-point favorite.

After 10,000 simulations of this matchup, our expertly tuned model projects the 49ers as having a 56% chance of covering the spread, while the Rams have a 44% chance.

• Pick ATS: 49ers -2.5

Baltimore Ravens vs. New York Giants (+16.5)

Simulations show a 53% chance of the Giants (+16.5) covering the spread at MetLife Stadium, while the Ravens have a 47% chance.

• Pick ATS: Giants +16.5

New York Jets vs. Jacksonville Jaguars (+3.5)

The Jaguars are listed as +3.5 underdogs against the Jets this week.

Our model projects the Jaguars as the more likely team to cover, with a probability of 56%, compared to 44% for the Jets.

• Pick ATS: Jaguars +3.5

Washington Commanders vs. New Orleans Saints (+7.5)

Our simulations give the Saints and Commanders each a 50% chance of covering the spread at Caesars Superdome on Sunday. However, if you need to make a pick, the Saints get a slight edge.

• Pick ATS: Saints +7.5

For those interested in betting on the spread, the oddsmakers have listed the Commanders at -105 to cover and the Saints at -110.

Cincinnati Bengals vs. Tennessee Titans (+4.5)

On the road against the Titans, the Bengals are 4.5-point favorites.

Our model projects a 51% chance of the Bengals covering the spread, while the Titans have a 49% chance.

• Pick ATS: Bengals -4.5

Miami Dolphins vs. Houston Texans (-3)

Our model projects a 58% chance of the Dolphins covering the spread against the Texans, who have a 42% chance.

The line is set with Houston as 3-point favorites at home.

• Pick ATS: Dolphins +3

Kansas City Chiefs vs. Cleveland Browns (+4.5)

In this game at Huntington Bank Field, the Chiefs are 4.5-point favorites at road.

According to our model, the Browns have a 52% chance of covering the spread, while the Chiefs have a 48% chance.

• Pick ATS: Browns +4.5

Dallas Cowboys vs. Carolina Panthers (-3)

Our model predicts the Cowboys to cover the spread in this game, giving them a 58% chance against the Panthers.

• Pick ATS: Cowboys +3

For those looking to place a bet, the line is set at Panthers -3, with the odds at -105 for the Panthers to cover at home and -112 for the Cowboys to cover on the road.

New England Patriots vs. Arizona Cardinals (-6.5)

Our simulations suggest a 54% chance of New England covering the spread, while the Cardinals have a 46% chance.

The hosting Cardinals are slight favorites with a 6.5-point spread in Week 15 against the Patriots.

• Pick ATS: Patriots +6.5

Tampa Bay Buccaneers vs. Los Angeles Chargers (-2.5)

The Chargers enter this matchup as 2.5-point favorites at home against the Buccaneers.

According to our simulations, both the Chargers and Buccaneers have a 50% chance of covering, with the Chargers slightly favored for those in against the spread pick contests.

• Pick ATS: Chargers +2.5

For those interested in betting on this line, the Buccaneers are listed at -100 to cover, with the Chargers at +120.

Buffalo Bills vs. Detroit Lions (-2.5)

Our model rates both the Lions and Bills as having a 50-50 shot of covering. If you're looking to make a pick here, our slight lean goes to the Lions.

• Pick ATS: Lions +2.5

Indianapolis Colts vs. Denver Broncos (-4)

The Broncos have a 51% chance of covering the spread on Sunday afternoon, compared to the Colts' 49% chance.

This makes the Broncos -4 our pick against the spread at SoFi Stadium.

• Pick ATS: Broncos -4

Pittsburgh Steelers vs. Philadelphia Eagles (-5.5)

We've run our powerful NFL model 10,000 times for this week’s Steelers-Eagles clash, with our model unable to split the two teams at the line.

With the sportsbooks nailing the 5.5-point gap between the teams, our pick is the Eagles to cover, who have a slightly higher probability.

• Pick ATS: Eagles -5.5

Green Bay Packers vs. Seattle Seahawks (+2.5)

Our simulations indicate a 58% chance of the Seahawks covering the spread in this matchup, while the Packers have a 42% chance.

This makes the Seahawks a strong pick against the spread for the Week 15 game at Lumen Field.

• Pick ATS: Seahawks +2.5

Chicago Bears vs. Minnesota Vikings (-7)

We are picking the Bears to cover the spread in their game against the Vikings this week.

According to our trusted NFL model, there is a 53% chance that the road team will cover the +7 line, while the Vikings have a 47% chance on Monday Night Football.

• Pick ATS: Bears +7

Atlanta Falcons vs. Las Vegas Raiders (+4)

The final game of Week 15 features the Falcons taking on the Raiders at Allegiant Stadium.

We are picking the Falcons to cover the spread, with a projected 53% chance of covering, while the Raiders have a 47% likelihood of covering the spread.

• Pick ATS: Falcons -4

Complete List of NFL Week 15 Picks Against the Spread:

• 49ers -2.5 (56%)
• Giants +16.5 (53%)
• Jaguars +3.5 (56%)
• Saints +7.5 (slight lean)
• Bengals -4.5 (51%)
• Dolphins +3 (58%)
• Browns +4.5 (52%)
• Cowboys +3 (58%)
• Patriots +6.5 (54%)
• Chargers +2.5 (slight lean)
• Lions +2.5 (slight lean)
• Broncos -4 (51%)
• Eagles -5.5 (slight lean)
• Seahawks +2.5 (58%)
• Bears +7 (53%)
• Falcons -4 (53%)

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NFL Week 15 Slate and Game Times

Below is the schedule and start times for each Week 15 matchup, so you can catch every moment of the action.

• Rams vs. 49ers (Thursday, 8:15PM ET)
• Ravens vs. Giants (Sunday, 1:00PM ET)
• Jets vs. Jaguars (Sunday, 1:00PM ET)
• Commanders vs. Saints (Sunday, 1:00PM ET)
• Bengals vs. Titans (Sunday, 1:00PM ET)
• Dolphins vs. Texans (Sunday, 1:00PM ET)
• Chiefs vs. Browns (Sunday, 1:00PM ET)
• Cowboys vs. Panthers (Sunday, 1:00PM ET)
• Patriots vs. Cardinals (Sunday, 4:25PM ET)
• Buccaneers vs. Chargers (Sunday, 4:25PM ET)
• Bills vs. Lions (Sunday, 4:25PM ET)
• Colts vs. Broncos (Sunday, 4:25PM ET)
• Steelers vs. Eagles (Sunday, 4:25PM ET)
• Packers vs. Seahawks (Sunday, 8:20PM ET)
• Bears vs. Vikings (Monday, 8:00PM ET)
• Falcons vs. Raiders (Monday, 8:30PM ET)

Week 15 NFL Picks Against Spread

The NFL Week 15 picks against the spread in this article are accurate at the time of publication and may be subject to change.

Football fans across the country rely on our NFL expert picks against the spread because Dimers.com is the best website for NFL predictions.

If you choose to use our NFL spread picks for betting, it's crucial to gamble responsibly and keep track of your money. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Please note that all NFL odds and probabilities on this page are subject to change.

Conclusion

Our Week 15 NFL picks against the spread start with the 49ers -2.5 at a 56% probability on Thursday Night Football, with the week concluding as we pick the Falcons -4 with a probability of 53%.

For more Week 15 betting tools, explore our NFL odds, NFL prop bets, NFL trends and NFL futures.