NFL Odds Week 6: Spreads, Moneylines, Totals for Every Game [2024]

Week 6 of the NFL season is here, bringing the latest spreads, moneylines and totals for each matchup.

Prepare for an exciting week of NFL football with 14 games on the schedule, providing fans ample opportunities to both watch and bet.

The action starts with a Thursday night clash between the San Francisco 49ers and Seattle Seahawks. The Seahawks are 3.5-point underdogs, setting the stage for a tightly contested matchup.

Below, you'll find comprehensive Vegas odds and information for each game, ensuring you have the best NFL odds at your fingertips to confidently place your NFL best bets.

NFL Week 6	Spread	Moneyline	Total
49ers vs. Seahawks	-3.5 (-105) +3.5 (-110)	-180 +155	o49.5 (-110) u49.5 (-110)
Jaguars vs. Bears	+1.5 (-105) -1.5 (-115)	+114 -126	o44.5 (-105) u44.5 (-110)
Buccaneers vs. Saints	--3.5 (-102) +3.5 (-110)	-170 +155	o41.5 (-108) u41.5 (-110)
Cardinals vs. Packers	+5 (-105) -5 (-112)	+205 -230	o47.5 (-110) u47.5 (-105)
Colts vs. Titans	+2.5 (-108) -2.5 (-110)	+120 -135	o43.5 (-106) u43.5 (-114)
Browns vs. Eagles	+9 (-108) -9 (-110)	+370 -450	o42.5 (-110) u42.5 (-105)
Texans vs. Patriots	-7 (-108) +7 (-110)	-310 +270	o38 (-108) u38 (-112)
Commanders vs. Ravens	+6.5 (-108) -6.5 (-108)	+245 -290	o51.5 (-105) u51.5 (-110)
Chargers vs. Broncos	-2.5 (-115) +2.5 (-102)	-148 +130	o35.5 (-108) u35.5 (-108)
Falcons vs. Panthers	-6.5 (-104) +6.5 (-118)	-260 +220	o46.5 (-115) u46.5 (-105)
Lions vs. Cowboys	-3 (-112) +3 (-105)	-155 +142	o52.5 (-105) u52.5 (-115)
Bengals vs. Giants	-3.5 (-102) +3.5 (-115)	-168 +150	o48.5 (-105) u48.5 (-115)
Bills vs. Jets	-2.5 (-108) +2.5 (-108)	-135 +120	o41 (-108) u41 (-110)

This article is part of Dimers.com's extensive weekly NFL predictions and NFL odds coverage.

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For more NFL betting insights, explore our NFL picks against the spread for Week 6 and NFL Week 6 straight up picks.

NFL Odds for Every Game of NFL Week 6

49ers vs. Seahawks Odds

• Matchup: San Francisco 49ers vs. Seattle Seahawks
• Spread: 49ers -3.5 (-105), Seahawks +3.5 (-110)
• Total: Over/Under 49.5 (-110/-110)
• Moneyline: 49ers -180, Seahawks +155
• Dimers' Win Probabilities: 49ers 60%, Seahawks 40%
• Date: Thursday, October 10, 2024
• Time: 8:15pm
• Venue: Lumen Field

In what appears to be a tight matchup, the Seahawks are 3.5-point underdogs on Thursday Night Football against the 49ers. The total line is set at 49.5 points, which is considered high for the over/under.

The NFL Week 6 action between the 49ers and Seahawks at Lumen Field is scheduled for 8:15pm on Thursday. For detailed analysis, see our full 49ers vs Seahawks prediction.

Jaguars vs. Bears Odds

• Matchup: Jacksonville Jaguars vs. Chicago Bears
• Spread: Jaguars +1.5 (-105), Bears -1.5 (-115)
• Total: Over/Under 44.5 (-105/-110)
• Moneyline: Jaguars +114, Bears -126
• Dimers' Win Probabilities: Jaguars 43%, Bears 57%
• Date: Sunday, October 13, 2024
• Time: 9:30am ET
• Venue: Tottenham Hotspur Stadium

In what is expected to be a close game, the Bears are 1.5-point favorites in their clash against the Jaguars. The total line is set at 44.5 points.

The action between the Jaguars and Bears at Tottenham Hotspur Stadium is scheduled for 9:30am on Sunday. For Dimers' full betting preview, check out our Jaguars vs Bears prediction.

Buccaneers vs. Saints Odds

• Matchup: Tampa Bay Buccaneers vs. New Orleans Saints
• Spread: Buccaneers -3.5 (-102), Saints +3.5 (-110)
• Total: Over/Under 41.5 (-108/-110)
• Moneyline: Buccaneers -170, Saints +155
• Dimers' Win Probabilities: Buccaneers 62%, Saints 38%
• Date: Sunday, October 13, 2024
• Time: 1:00pm ET
• Venue: Caesars Superdome

In what is expected to be a close game, the Saints are 3.5-point underdogs in their clash against the Buccaneers. The total line is set at 41.5 points.

This week's action between the Buccaneers and Saints at Caesars Superdome is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full Buccaneers vs Saints prediction.

Cardinals vs. Packers Odds

• Matchup: Arizona Cardinals vs. Green Bay Packers
• Spread: Cardinals +5 (-105), Packers -5 (-112)
• Total: Over/Under 47.5 (-110/-105)
• Moneyline: Cardinals +205, Packers -230
• Dimers' Win Probabilities: Cardinals 32%, Packers 68%
• Date: Sunday, October 13, 2024
• Time: 1:00pm ET
• Venue: Lambeau Field

By around a touchdown, the Packers face a -5 point spread as favorites in their clash against the Cardinals. The total line is set at 47.5 points, which is considered high for the over/under.

The NFL Week 6 game between the Cardinals and Packers at Lambeau Field begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Cardinals vs Packers prediction.

Colts vs. Titans Odds

• Matchup: Indianapolis Colts vs. Tennessee Titans
• Spread: Colts +2.5 (-108), Titans -2.5 (-110)
• Total: Over/Under 43.5 (-106/-114)
• Moneyline: Colts +120, Titans -135
• Dimers' Win Probabilities: Colts 42%, Titans 58%
• Date: Sunday, October 13, 2024
• Time: 1:00pm ET
• Venue: Nissan Stadium

In what appears to be a tight matchup, the Titans are 2.5-point favorites in their clash against the Colts. The total line is set at 43.5 points.

The clash between the Colts and Titans at Nissan Stadium begins at 1:00pm on Sunday. For more detailed analysis, check out our full Colts vs Titans prediction.

Browns vs. Eagles Odds

• Matchup: Cleveland Browns vs. Philadelphia Eagles
• Spread: Browns +9 (-108), Eagles -9 (-110)
• Total: Over/Under 42.5 (-110/-105)
• Moneyline: Browns +370, Eagles -450
• Dimers' Win Probabilities: Browns 20%, Eagles 80%
• Date: Sunday, October 13, 2024
• Time: 1:00pm ET
• Venue: Lincoln Financial Field

Holding a solid advantage, the Eagles are 9-point favorites at the spread in their clash against the Browns. The total line is set at 42.5 points.

This week's game between the Browns and Eagles at Lincoln Financial Field begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Browns vs Eagles prediction.

Texans vs. Patriots Odds

• Matchup: Houston Texans vs. New England Patriots
• Spread: Texans -7 (-108), Patriots +7 (-110)
• Total: Over/Under 38 (-108/-112)
• Moneyline: Texans -310, Patriots +270
• Dimers' Win Probabilities: Texans 79%, Patriots 21%
• Date: Sunday, October 13, 2024
• Time: 1:00pm ET
• Venue: Gillette Stadium

By around a touchdown, the Patriots face a +7 point spread as underdogs in their clash against the Texans. The total line is set at 38 points, which is considered low for the over/under.

The NFL Week 6 action between the Texans and Patriots at Gillette Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Texans vs Patriots prediction.

Commanders vs. Ravens Odds

• Matchup: Washington Commanders vs. Baltimore Ravens
• Spread: Commanders +6.5 (-108), Ravens -6.5 (-108)
• Total: Over/Under 51.5 (-105/-110)
• Moneyline: Commanders +245, Ravens -290
• Dimers' Win Probabilities: Commanders 30%, Ravens 70%
• Date: Sunday, October 13, 2024
• Time: 1:00pm ET
• Venue: M&T Bank Stadium

By roughly a touchdown, the Ravens face a -6.5 point spread as favorites in their clash against the Commanders. Witha high-scoring affair anticipated, the over/under is set at 51.5 points.

The game between the Commanders and Ravens at M&T Bank Stadium is scheduled for 1:00pm on Sunday. For Dimers' full betting preview, check out our Commanders vs Ravens prediction.

Chargers vs. Broncos Odds

• Matchup: Los Angeles Chargers vs. Denver Broncos
• Spread: Chargers -2.5 (-115), Broncos +2.5 (-102)
• Total: Over/Under 35.5 (-108/-108)
• Moneyline: Chargers -148, Broncos +130
• Dimers' Win Probabilities: Chargers 64%, Broncos 36%
• Date: Sunday, October 13, 2024
• Time: 4:05pm ET
• Venue: Empower Field at Mile High

In a game likely to be closely contested, the Broncos are 2.5-point underdogs in their clash against the Chargers. The total line is set at 35.5 points, which is considered low for the over/under.

This week's clash between the Chargers and Broncos at Empower Field at Mile High kicks off at 4:05pm on Sunday. For more detailed analysis, check out our full Chargers vs Broncos prediction.

Steelers vs. Raiders Odds

• Matchup: Pittsburgh Steelers vs. Las Vegas Raiders
• Spread: Steelers -3 (-105), Raiders +3 (-105)
• Total: Over/Under 36.5 (-110/-108)
• Moneyline: Steelers -162, Raiders +145
• Dimers' Win Probabilities: Steelers 64%, Raiders 36%
• Date: Sunday, October 13, 2024
• Time: 4:05pm ET
• Venue: Allegiant Stadium

In a closely projected game, the Raiders are 3-point underdogs in their clash against the Steelers. The total line is set at 36.5 points, which is considered low for the over/under.

The NFL Week 6 matchup between the Steelers and Raiders at Allegiant Stadium begins at 4:05pm on Sunday. For Dimers' full betting preview, check out our Steelers vs Raiders prediction.

Falcons vs. Panthers Odds

• Matchup: Atlanta Falcons vs. Carolina Panthers
• Spread: Falcons -6.5 (-104), Panthers +6.5 (-118)
• Total: Over/Under 46.5 (-115/-105)
• Moneyline: Falcons -260, Panthers +220
• Dimers' Win Probabilities: Falcons 70%, Panthers 30%
• Date: Sunday, October 13, 2024
• Time: 4:25pm ET
• Venue: Bank of America Stadium

By roughly a touchdown, the Panthers face a +6.5 point spread as underdogs in their clash against the Falcons. The total line is set at 46.5 points, which is considered high for the over/under.

The action between the Falcons and Panthers at Bank of America Stadium kicks off at 4:25pm on Sunday. For more detailed analysis, check out our full Falcons vs Panthers prediction.

Lions vs. Cowboys Odds

• Matchup: Detroit Lions vs. Dallas Cowboys
• Spread: Lions -3 (-112), Cowboys +3 (-105)
• Total: Over/Under 52.5 (-105/-115)
• Moneyline: Lions -155, Cowboys +142
• Dimers' Win Probabilities: Lions 60%, Cowboys 40%
• Date: Sunday, October 13, 2024
• Time: 4:25pm ET
• Venue: AT&T Stadium

In a game likely to be closely contested, the Cowboys are 3-point underdogs in their clash against the Lions. Witha high-scoring affair anticipated, the over/under is set at 52.5 points.

This week's action between the Lions and Cowboys at AT&T Stadium begins at 4:25pm on Sunday. For Dimers' full betting preview, check out our Lions vs Cowboys prediction.

Bengals vs. Giants Odds

• Matchup: Cincinnati Bengals vs. New York Giants
• Spread: Bengals -3.5 (-102), Giants +3.5 (-115)
• Total: Over/Under 48.5 (-105/-115)
• Moneyline: Bengals -168, Giants +150
• Dimers' Win Probabilities: Bengals 63%, Giants 37%
• Date: Sunday, October 13, 2024
• Time: 8:20pm ET
• Venue: MetLife Stadium

In what appears to be a tight matchup, the Giants are 3.5-point underdogs in their Sunday Night Football clash against the Bengals. The total line is set at 48.5 points, which is considered high for the over/under.

The NFL Week 6 matchup between the Bengals and Giants at MetLife Stadium begins at 8:20pm on Sunday. For more detailed analysis, check out our full Bengals vs Giants prediction.

Bills vs. Jets Odds

• Matchup: Buffalo Bills vs. New York Jets
• Spread: Bills -2.5 (-108), Jets +2.5 (-108)
• Total: Over/Under 41 (-108/-110)
• Moneyline: Bills -135, Jets +120
• Dimers' Win Probabilities: Bills 59%, Jets 41%
• Date: Monday, October 14, 2024
• Time: 8:15pm ET
• Venue: MetLife Stadium

In a closely projected game, the Jets are 2.5-point underdogs in their Monday Night Football clash against the Bills. The total line is set at 41 points.

The clash between the Bills and Jets at MetLife Stadium begins at 8:15pm on Monday. For Dimers' full betting preview, check out our Bills vs Jets prediction.

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NFL Odds: Week 6

Discover the odds for each NFL Week 6 matchup. Please note that these odds are accurate at the time of publication and may change.

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Conclusion

As Week 6 approaches, these NFL odds ensure you're ready for every game, right up to the game between the Bills and Jets on Monday Night Football, where the Bills are favored by 2.5 points.

For more Week 6 betting coverage, view our NFL picks, NFL prop bets, NFL trends and NFL futures.