NFL Odds Week 4: Spreads, Moneylines, Totals for Every Game [2024]

Week 4 of the NFL season is here, bringing the latest spreads, moneylines and totals for each matchup.

As we head into Week 4 of the NFL season, the schedule is stacked with matchups that promise excitement and plenty of betting opportunities.

The action starts with a Thursday night clash between the Dallas Cowboys and New York Giants. The Giants enter as 5.5-point underdogs, pointing to a competitive game to open the week.

Below, you'll find detailed Vegas odds and key information for each game, ensuring you have the best NFL odds at your fingertips to confidently place your NFL best bets.

This article is part of Dimers.com's comprehensive weekly NFL predictions and NFL odds coverage.

Maximize your NFL betting experience with Dimers Pro. As a subscriber, you'll enjoy unlimited access to our data-driven insights and analysis. Join now and bet smarter.

Sign up with code 20FOOTBALL at checkout right now to receive 20% off your first month of Dimers Pro! This offer won't last forever.

For more NFL betting insights, explore our NFL Week 4 straight up picks.

NFL Odds for Every Game of NFL Week 4

Cowboys vs. Giants Odds

• Matchup: Dallas Cowboys vs. New York Giants
• Spread: Cowboys -5.5 (-110), Giants +5.5 (-108)
• Total: Over/Under 45.5 (-105/-112)
• Moneyline: Cowboys -245, Giants +200
• Dimers' Win Probabilities: Cowboys 69%, Giants 31%
• Date: Thursday, September 26, 2024
• Time: 8:15pm
• Venue: MetLife Stadium

By roughly a touchdown, the Giants face a +5.5 point spread as underdogs on Thursday Night Football against the Cowboys. The total line is set at 45.5 points, which is considered high for the over/under.

The NFL Week 4 action between the Cowboys and Giants at MetLife Stadium is scheduled for 8:15pm on Thursday. For detailed analysis, see our full Cowboys vs Giants prediction.

Steelers vs. Colts Odds

• Matchup: Pittsburgh Steelers vs. Indianapolis Colts
• Spread: Steelers -1.5 (-112), Colts +1.5 (-105)
• Total: Over/Under 39.5 (-115/-105)
• Moneyline: Steelers -122, Colts +110
• Dimers' Win Probabilities: Steelers 59%, Colts 41%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: Lucas Oil Stadium

In a game likely to be closely contested, the Colts are 1.5-point underdogs in their clash against the Steelers. The total line is set at 39.5 points, which is considered low for the over/under.

The action between the Steelers and Colts at Lucas Oil Stadium is scheduled for 1:00pm on Sunday. For Dimers' full betting preview, check out our Steelers vs Colts prediction.

Vikings vs. Packers Odds

• Matchup: Minnesota Vikings vs. Green Bay Packers
• Spread: Vikings +2.5 (-112), Packers -2.5 (-115)
• Total: Over/Under 43.5 (-110/-108)
• Moneyline: Vikings +122, Packers -135
• Dimers' Win Probabilities: Vikings 42%, Packers 58%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: Lambeau Field

In a closely projected game, the Packers are 2.5-point favorites in their clash against the Vikings. The total line is set at 43.5 points.

This week's action between the Vikings and Packers at Lambeau Field is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full Vikings vs Packers prediction.

Jaguars vs. Texans Odds

• Matchup: Jacksonville Jaguars vs. Houston Texans
• Spread: Jaguars +7 (-110), Texans -7 (-105)
• Total: Over/Under 45 (-110/-108)
• Moneyline: Jaguars +260, Texans -295
• Dimers' Win Probabilities: Jaguars 27%, Texans 73%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: NRG Stadium

By around a touchdown, the Texans face a -7 point spread as favorites in their clash against the Jaguars. The total line is set at 45 points.

The NFL Week 4 game between the Jaguars and Texans at NRG Stadium begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Jaguars vs Texans prediction.

Saints vs. Falcons Odds

• Matchup: New Orleans Saints vs. Atlanta Falcons
• Spread: Saints +1.5 (-110), Falcons -1.5 (-108)
• Total: Over/Under 42.5 (-110/-110)
• Moneyline: Saints +105, Falcons -120
• Dimers' Win Probabilities: Saints 44%, Falcons 56%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: Mercedes-Benz Stadium

In what is expected to be a close game, the Falcons are 1.5-point favorites in their clash against the Saints. The total line is set at 42.5 points.

The matchup between the Saints and Falcons at Mercedes-Benz Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Saints vs Falcons prediction.

Rams vs. Bears Odds

• Matchup: Los Angeles Rams vs. Chicago Bears
• Spread: Rams +2 (+100), Bears -2 (-130)
• Total: Over/Under 41 (-108/-110)
• Moneyline: Rams +132, Bears -142
• Dimers' Win Probabilities: Rams 40%, Bears 60%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: Soldier Field

In what is expected to be a close game, the Bears are 2-point favorites in their clash against the Rams. The total line is set at 41 points.

This week's action between the Rams and Bears at Soldier Field kicks off at 1:00pm on Sunday. For Dimers' full betting preview, check out our Rams vs Bears prediction.

Eagles vs. Buccaneers Odds

• Matchup: Philadelphia Eagles vs. Tampa Bay Buccaneers
• Spread: Eagles -2.5 (-110), Buccaneers +2.5 (-110)
• Total: Over/Under 44.5 (-115/-105)
• Moneyline: Eagles -135, Buccaneers +120
• Dimers' Win Probabilities: Eagles 57%, Buccaneers 43%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: Raymond James Stadium

In a closely projected game, the Buccaneers are 2.5-point underdogs in their clash against the Eagles. The total line is set at 44.5 points.

The NFL Week 4 game between the Eagles and Buccaneers at Raymond James Stadium is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full Eagles vs Buccaneers prediction.

Bengals vs. Panthers Odds

• Matchup: Cincinnati Bengals vs. Carolina Panthers
• Spread: Bengals -4.5 (-110), Panthers +4.5 (-110)
• Total: Over/Under 48.5 (-104/-112)
• Moneyline: Bengals -205, Panthers +184
• Dimers' Win Probabilities: Bengals 65%, Panthers 35%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: Bank of America Stadium

According to the sportsbooks, the Panthers are 4.5-point underdogs in their clash against the Bengals. The total line is set at 48.5 points, which is considered high for the over/under.

The game between the Bengals and Panthers at Bank of America Stadium begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Bengals vs Panthers prediction.

Broncos vs. Jets Odds

• Matchup: Denver Broncos vs. New York Jets
• Spread: Broncos +7.5 (-110), Jets -7.5 (-105)
• Total: Over/Under 38.5 (-110/-110)
• Moneyline: Broncos +295, Jets -345
• Dimers' Win Probabilities: Broncos 22%, Jets 78%
• Date: Sunday, September 29, 2024
• Time: 1:00pm ET
• Venue: MetLife Stadium

By around a touchdown, the Jets face a -7.5 point spread as favorites in their clash against the Broncos. The total line is set at 38.5 points, which is considered low for the over/under.

This week's action between the Broncos and Jets at MetLife Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Broncos vs Jets prediction.

Commanders vs. Cardinals Odds

• Matchup: Washington Commanders vs. Arizona Cardinals
• Spread: Commanders +3.5 (-115), Cardinals -3.5 (+100)
• Total: Over/Under 50.5 (-110/-110)
• Moneyline: Commanders +154, Cardinals -170
• Dimers' Win Probabilities: Commanders 39%, Cardinals 61%
• Date: Sunday, September 29, 2024
• Time: 4:05pm ET
• Venue: State Farm Stadium

In what is expected to be a close game, the Cardinals are 3.5-point favorites in their clash against the Commanders. With a high-scoring affair anticipated, the over/under is set at 50.5 points.

The NFL Week 4 clash between the Commanders and Cardinals at State Farm Stadium begins at 4:05pm on Sunday. For Dimers' full betting preview, check out our Commanders vs Cardinals prediction.

Patriots vs. 49ers Odds

• Matchup: New England Patriots vs. San Francisco 49ers
• Spread: Patriots +10 (-108), 49ers -10 (-110)
• Total: Over/Under 39.5 (-110/-110)
• Moneyline: Patriots +420, 49ers -520
• Dimers' Win Probabilities: Patriots 17%, 49ers 83%
• Date: Sunday, September 29, 2024
• Time: 4:05pm ET
• Venue: Levi's Stadium

A considerable spread makes the 49ers 10-point favorites in their clash against the Patriots. The total line is set at 39.5 points, which is considered low for the over/under.

The matchup between the Patriots and 49ers at Levi's Stadium kicks off at 4:05pm on Sunday. For more detailed analysis, check out our full Patriots vs 49ers prediction.

Browns vs. Raiders Odds

• Matchup: Cleveland Browns vs. Las Vegas Raiders
• Spread: Browns -1.5 (-102), Raiders +1.5 (-120)
• Total: Over/Under 37 (-110/-108)
• Moneyline: Browns -105, Raiders -104
• Dimers' Win Probabilities: Browns 45%, Raiders 55%
• Date: Sunday, September 29, 2024
• Time: 4:25pm ET
• Venue: Allegiant Stadium

In a closely projected game, the Raiders are 1.5-point underdogs in their clash against the Browns. The total line is set at 37 points, which is considered low for the over/under.

This week's matchup between the Browns and Raiders at Allegiant Stadium kicks off at 4:25pm on Sunday. For Dimers' full betting preview, check out our Browns vs Raiders prediction.

Chiefs vs. Chargers Odds

• Matchup: Kansas City Chiefs vs. Los Angeles Chargers
• Spread: Chiefs -8 (-112), Chargers +8 (-108)
• Total: Over/Under 39 (-110/-108)
• Moneyline: Chiefs -410, Chargers +340
• Dimers' Win Probabilities: Chiefs 79%, Chargers 21%
• Date: Sunday, September 29, 2024
• Time: 4:25pm ET
• Venue: SoFi Stadium

Up against a formidable challenge, the Chargers are8 -point underdogs at the spread in their clash against the Chiefs. The total line is set at 39 points, which is considered low for the over/under.

The NFL Week 4 matchup between the Chiefs and Chargers at SoFi Stadium begins at 4:25pm on Sunday. For more detailed analysis, check out our full Chiefs vs Chargers prediction.

Bills vs. Ravens Odds

• Matchup: Buffalo Bills vs. Baltimore Ravens
• Spread: Bills +2.5 (-108), Ravens -2.5 (-110)
• Total: Over/Under 46.5 (-110/-110)
• Moneyline: Bills +116, Ravens -135
• Dimers' Win Probabilities: Bills 41%, Ravens 59%
• Date: Sunday, September 29, 2024
• Time: 8:20pm ET
• Venue: M&T Bank Stadium

In what is expected to be a close game, the Ravens are 2.5-point favorites in their Sunday Night Football clash against the Bills. The total line is set at 46.5 points, which is considered high for the over/under.

The action between the Bills and Ravens at M&T Bank Stadium begins at 8:20pm on Sunday. For Dimers' full betting preview, check out our Bills vs Ravens prediction.

Titans vs. Dolphins Odds

• Matchup: Tennessee Titans vs. Miami Dolphins
• Spread: Titans +1 (-115), Dolphins -1 (-105)
• Total: Over/Under 36.5 (-115/-105)
• Moneyline: Titans -108, Dolphins -108
• Dimers' Win Probabilities: Titans 48%, Dolphins 52%
• Date: Monday, September 30, 2024
• Time: 7:30pm ET
• Venue: Hard Rock Stadium

In a closely projected game, the Dolphins are 1-point favorites on Monday Night Football against the Chiefs. The total line is set at 36.5 points, which is considered low for the over/under.

This week's action between the Titans and Dolphins at Hard Rock Stadium kicks off at 7:30pm on Monday. For more detailed analysis, check out our full Titans vs Dolphins prediction.

Seahawks vs. Lions Odds

• Matchup: Seattle Seahawks vs. Detroit Lions
• Spread: Seahawks +3.5 (-105), Lions -3.5 (-110)
• Total: Over/Under 46.5 (-115/-105)
• Moneyline: Seahawks +162, Lions -180
• Dimers' Win Probabilities: Seahawks 38%, Lions 62%
• Date: Monday, September 30, 2024
• Time: 8:15pm ET
• Venue: Ford Field

In what appears to be a tight matchup, the Lions are 3.5-point favorites on Monday Night Football against the Seahawks. The total line is set at 46.5 points, which is considered high for the over/under.

The NFL Week 4 action between the Seahawks and Lions at Ford Field begins at 8:15pm on Monday. For Dimers' full betting preview, check out our Seahawks vs Lions prediction.

NFL Fantasy and Betting Promotions

Make the most of this week's NFL games by exploring the two exciting offers below.

DraftKings Pick6

Sign up for DraftKings Pick6 today! Play $5 and get $50 in Pick6 Credits, plus one month of NFL RedZone access.

FanDuel Sportsbook

Get ready for NFL Week 4 by joining FanDuel Sportsbook! Bet $5 and get $200 in bonus bets.

NFL Odds: Week 4

Discover the odds for each NFL Week 4 matchup. Please note that these odds are accurate at the time of publication and may change.

If you're using these odds for betting, it's important to gamble responsibly and know your limits. For additional resources and support, call 1-800-GAMBLER.

Conclusion

As Week 4 approaches, these NFL odds ensure you're ready for every game, right up to the game between the Seahawks and Lions on Monday Night Football, where the Lions are favored by 3.5 points.

For more Week 4 betting coverage, view our NFL picks, NFL prop bets, NFL trends and NFL futures.