NFL Odds Week 16: Spreads, Moneylines, Totals for Every Game [2024]

Week 16 of the NFL season has arrived, and with it comes the latest spreads, moneylines and totals for every matchup.

As the postseason looms, the stakes are higher than ever as teams fight for crucial playoff spots and positioning.

The action starts with a Thursday night showdown between the Denver Broncos and Los Angeles Chargers. The Chargers enter as 3-point favorites, setting the stage for a tightly contested matchup.

Below, you'll find comprehensive Vegas odds and key information for each game, ensuring you have the best NFL odds at your fingertips to confidently place your NFL best bets.

NFL Week 16	Spread	Moneyline	Total
Broncos vs. Chargers	+3 (-118) -3 (-102)	+130 -150	o41.5 (-110) u41.5 (-110)
Texans vs. Chiefs	+3.5 (-110) -3.5 (-104)	+165 -174	o41.5 (-115) u41.5 (-105)
Steelers vs. Ravens	-+6.5 (-110) -6.5 (-105)	+240 -278	o44.5 (-110) u44.5 (-108)
Browns vs. Bengals	+8.5 (-105) -8.5 (-108)	+380 -450	o46.5 (-112) u46.5 (-105)
Giants vs. Falcons	+8.5 (-110) -8.5 (-110)	+360 -440	o42 (-112) u42 (-108)
Lions vs. Bears	-6.5 (-110) +6.5 (-105)	-295 +245	o47.5 (-115) u47.5 (-105)
Titans vs. Colts	+3.5 (-105) -3.5 (-108)	+166 -190	o42.5 (-110) u42.5 (-110)
Cardinals vs. Panthers	-4.5 (-110) +4.5 (-110)	-215 +185	o47 (-110) u47 (-108)
Eagles vs. Commanders	-3.5 (-105) +3.5 (-110)	-180 +152	o45.5 (-110) u45.5 (-108)
Vikings vs. Seahawks	-3 (-105) +3 (-108)	-155 +142	o42.5 (-108) u42.5 (-110)
Patriots vs. Bills	+14 (-108) -14 (-110)	+750 -1000	o46.5 (-108) u46.5 (-105)
Jaguars vs. Raiders	+1.5 (-110) -1.5 (-110)	+106 -118	o40 (-110) u40 (-110)
49ers vs. Dolphins	+1 (-115) -1 (-105)	-106 -110	o44.5 (-110) u44.5 (-105)
Buccaneers vs. Cowboys	-4 (-108) +4 (-110)	-198 +170	o48.5 (-108) u48.5 (-110)
Saints vs. Packers	+14.5 (-115) -14.5 (-105)	+700 -900	o42.5 (-105) u42.5 (-110)

This article is part of Dimers.com's extensive weekly NFL predictions and NFL odds coverage.

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For more NFL betting insights, explore our NFL picks against the spread for Week 16 and NFL Week 16 straight up picks.

Full List of NFL Odds for Every Game of NFL Week 16

Broncos vs. Chargers Odds

• Spread: Broncos +3 (-118), Chargers -3 (-102)
• Total: Over/Under 41.5 (-110/-110)
• Moneyline: Broncos +130, Chargers -150

In a closely projected game, the Chargers are 3-point favorites on Thursday Night Football against the Broncos. The total line is set at 41.5 points.

The NFL Week 16 game between the Broncos and Chargers at SoFi Stadium kicks off at 8:15pm on Thursday. For detailed analysis, see our full Broncos vs Chargers prediction.

Texans vs. Chiefs Odds

• Spread: Texans +3.5 (-110), Chiefs -3.5 (-104)
• Total: Over/Under 41.5 (-115/-105)
• Moneyline: Texans +165, Chiefs -174

In a closely projected game, the Chiefs are 3.5-point favorites in their clash against the Texans. The total line is set at 41.5 points.

The matchup between the Texans and Chiefs at GEHA Field at Arrowhead Stadium kicks off at 1:00pm on Saturday. For Dimers' full betting preview, check out our Texans vs Chiefs prediction.

Steelers vs. Ravens Odds

• Spread: Steelers +6.5 (-110), Ravens -6.5 (-105)
• Total: Over/Under 44.5 (-110/-108)
• Moneyline: Steelers +240, Ravens -278

By roughly a touchdown, the Ravens face a -6.5 point spread as favorites in their clash against the Steelers. The total line is set at 44.5 points.

This week's matchup between the Steelers and Ravens at M&T Bank Stadium begins at 4:30pm on Saturday. For more detailed analysis, check out our full Steelers vs Ravens prediction.

Browns vs. Bengals Odds

• Spread: Browns +8.5 (-105), Bengals -8.5 (-108)
• Total: Over/Under 46.5 (-112/-105)
• Moneyline: Browns +380, Bengals -450

Holding a solid advantage, the Bengals are 8.5-point favorites at the spread in their clash against the Browns. The total line is set at 46.5 points, which is considered high for the over/under.

The NFL Week 16 matchup between the Browns and Bengals at Paycor Stadium kicks off at 1:00pm on Sunday. For Dimers' full betting preview, check out our Browns vs Bengals prediction.

Giants vs. Falcons Odds

• Spread: Giants +8.5 (-110), Falcons -8.5 (-110)
• Total: Over/Under 42 (-112/-108)
• Moneyline: Giants +360, Falcons -440

Holding a solid advantage, the Falcons are 8.5-point favorites at the spread in their clash against the Giants. The total line is set at 42 points.

The matchup between the Giants and Falcons at Mercedes-Benz Stadium is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full Giants vs Falcons prediction.

Lions vs. Bears Odds

• Spread: Lions -6.5 (-110), Bears +6.5 (-105)
• Total: Over/Under 47.5 (-115/-105)
• Moneyline: Lions -295, Bears +245

By roughly a touchdown, the Bears face a +6.5 point spread as underdogs in their clash against the Lions. The total line is set at 47.5 points, which is considered high for the over/under.

This week's game between the Lions and Bears at Soldier Field kicks off at 1:00pm on Sunday. For Dimers' full betting preview, check out our Lions vs Bears prediction.

Titans vs. Colts Odds

• Spread: Titans +3.5 (-105), Colts -3.5 (-108)
• Total: Over/Under 42.5 (-110/-110)
• Moneyline: Titans +166, Colts -190

In a game likely to be closely contested, the Colts are 3.5-point favorites in their clash against the Titans. The total line is set at 42.5 points.

The NFL Week 16 game between the Titans and Colts at Lucas Oil Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Titans vs Colts prediction.

Cardinals vs. Panthers Odds

• Spread: Cardinals -4.5 (-110), Panthers +4.5 (-110)
• Total: Over/Under 47 (-110/-108)
• Moneyline: Cardinals -215, Panthers +185

According to the oddsmakers, the Panthers are 4.5-point underdogs in their clash against the Cardinals. The total line is set at 47 points, which is considered high for the over/under.

The clash between the Cardinals and Panthers at Bank of America Stadium begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Cardinals vs Panthers prediction.

Eagles vs. Commanders Odds

• Spread: Eagles -3.5 (-105), Commanders +3.5 (-110)
• Total: Over/Under 45.5 (-110/-108)
• Moneyline: Eagles -180, Commanders +152

In a game likely to be closely contested, the Commanders are 3.5-point underdogs in their clash against the Eagles. The total line is set at 45.5 points, which is considered high for the over/under.

This week's clash between the Eagles and Commanders at Northwest Stadium is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full Eagles vs Commanders prediction.

Rams vs. Jets Odds

• Spread: Rams -3 (-105), Jets +3 (-110)
• Total: Over/Under 46.5 (-110/-110)
• Moneyline: Rams -152, Jets +140

In what appears to be a tight matchup, the Jets are 3-point underdogs in their clash against the Rams. The total line is set at 46.5 points, which is considered high for the over/under.

The NFL Week 16 clash between the Rams and Jets at MetLife Stadium kicks off at 1:00pm on Sunday. For Dimers' full betting preview, check out our Rams vs Jets prediction.

Vikings vs. Seahawks Odds

• Spread: Vikings -3 (-105), Seahawks +3 (-108)
• Total: Over/Under 42.5 (-108/-110)
• Moneyline: Vikings -155, Seahawks +142

In a closely projected game, the Seahawks are 3-point underdogs in their clash against the Vikings. The total line is set at 42.5 points.

The game between the Vikings and Seahawks at Lumen Field kicks off at 4:05pm on Sunday. For more detailed analysis, check out our full Vikings vs Seahawks prediction.

Patriots vs. Bills Odds

• Spread: Patriots +14 (-108), Bills -14 (-110)
• Total: Over/Under 46.5 (-108/-105)
• Moneyline: Patriots +750, Bills -1000

A double-digit spread has the Bills as 14-point favorites in their clash against the Patriots. The total line is set at 46.5 points, which is considered high for the over/under.

This week's action between the Patriots and Bills at Highmark Stadium kicks off at 4:25pm on Sunday. For Dimers' full betting preview, check out our Patriots vs Bills prediction.

Jaguars vs. Raiders Odds

• Spread: Jaguars +1.5 (-110), Raiders -1.5 (-110)
• Total: Over/Under 40 (-110/-110)
• Moneyline: Jaguars +106, Raiders -118

In a game likely to be closely contested, the Raiders are 1.5-point favorites in their clash against the Jaguars. The total line is set at 40 points.

The NFL Week 16 game between the Jaguars and Raiders at Allegiant Stadium is scheduled for 4:25pm on Sunday. For more detailed analysis, check out our full Jaguars vs Raiders prediction.

49ers vs. Dolphins Odds

• Spread: 49ers +1 (-115), Dolphins -1 (-105)
• Total: Over/Under 44.5 (-110/-105)
• Moneyline: 49ers -106, Dolphins -110

In what appears to be a tight matchup, the Dolphins are 1-point favorites in their clash against the 49ers. The total line is set at 44.5 points.

The matchup between the 49ers and Dolphins at Hard Rock Stadium begins at 4:25pm on Sunday. For Dimers' full betting preview, check out our 49ers vs Dolphins prediction.

Buccaneers vs. Cowboys Odds

• Spread: Buccaneers -4 (-108), Cowboys +4 (-110)
• Total: Over/Under 48.5 (-108/-110)
• Moneyline: Buccaneers -198, Cowboys +170

According to the sportsbooks, the Cowboys are 4-point underdogs on Sunday Night Football against the Jaguars. The total line is set at 48.5 points, which is considered high for the over/under.

This week's game between the Buccaneers and Cowboys at AT&T Stadium is scheduled for 8:20pm on Sunday. For more detailed analysis, check out our full Buccaneers vs Cowboys prediction.

Saints vs. Packers Odds

• Spread: Saints +14.5 (-115), Packers -14.5 (-105)
• Total: Over/Under 42.5 (-105/-110)
• Moneyline: Saints +700, Packers -900

A double-digit spread means the Packers are 14.5-point favorites on Monday Night Football against the Saints. The total line is set at 42.5 points.

The NFL Week 16 action between the Saints and Packers at Lambeau Field kicks off at 8:15pm on Monday. For Dimers' full betting preview, check out our Saints vs Packers prediction.

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NFL Odds: Week 16

Explore the odds for every NFL Week 16 game. Please note that these odds are accurate at the time of publication and may change.

If you're using these odds for betting, it's important to gamble responsibly and know your limits. For additional resources and support, call 1-800-GAMBLER.

Conclusion

As Week 16 approaches, these NFL odds ensure you're ready for every game, right up to the game between the Saints and Packers on Monday Night Football, where the Packers are favored by 14.5 points.

For more Week 16 betting coverage, view our NFL picks, NFL prop bets, NFL trends and NFL futures.