NFL Odds Week 15: Spreads, Moneylines, Totals for Every Game [2024]

Week 15 of the NFL season is here, bringing the latest spreads, moneylines and totals for every matchup.

As the postseason looms, each game gains added significance, with teams battling for playoff spots and positioning.

The action begins with a Thursday night clash between the Los Angeles Rams and San Francisco 49ers. The 49ers enter as 2.5-point favorites, setting the stage for a closely contested matchup.

Below, you'll find detailed Vegas odds and key information for each game, ensuring you have the best NFL odds at your fingertips to confidently place your NFL best bets.

NFL Week 15	Spread	Moneyline	Total
Rams vs. 49ers	+2.5 (-105) -2.5 (-125)	+134 -150	o49 (-110) u49 (-110)
Ravens vs. Giants	-16.5 (+100) +16.5 (-110)	-1350 +870	o42.5 (-110) u42.5 (-110)
Jets vs. Jaguars	--3.5 (-110) +3.5 (-115)	-166 +150	o40.5 (-105) u40.5 (-110)
Commanders vs. Saints	-7.5 (-105) +7.5 (-110)	-345 +310	o43.5 (-105) u43.5 (-108)
Bengals vs. Titans	-4.5 (-120) +4.5 (-102)	-230 +200	o46.5 (-110) u46.5 (-105)
Dolphins vs. Texans	+3 (-112) -3 (-105)	+130 -148	o46.5 (-110) u46.5 (-105)
Chiefs vs. Browns	-4.5 (-105) +4.5 (-115)	-215 +185	o43.5 (-110) u43.5 (-110)
Cowboys vs. Panthers	+3 (-112) -3 (-105)	+130 -145	o42.5 (-120) u42.5 (-102)
Patriots vs. Cardinals	+6.5 (-115) -6.5 (-105)	+215 -230	o46.5 (-104) u46.5 (-112)
Bills vs. Lions	+2.5 (+100) -2.5 (-110)	+124 -142	o54.5 (-110) u54.5 (-110)
Colts vs. Broncos	+4 (-110) -4 (-110)	+176 -198	o44 (-108) u44 (-110)
Steelers vs. Eagles	+5.5 (-110) -5.5 (-108)	+205 -225	o42.5 (-115) u42.5 (-105)
Packers vs. Seahawks	-2.5 (-115) +2.5 (-105)	-135 +125	o46.5 (-105) u46.5 (-115)
Bears vs. Vikings	+7 (-115) -7 (-102)	+260 -305	o44.5 (-108) u44.5 (-112)
Falcons vs. Raiders	-4 (-108) +4 (-112)	-200 +180	o44 (-110) u44 (-105)

This article is part of Dimers.com's extensive weekly NFL predictions and NFL odds coverage.

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For more NFL betting insights, explore our NFL picks against the spread for Week 15 and NFL Week 15 straight up picks.

Full List of NFL Odds for Every Game of NFL Week 15

Rams vs. 49ers Odds

• Spread: Rams +2.5 (-105), 49ers -2.5 (-125)
• Total: Over/Under 49 (-110/-110)
• Moneyline: Rams +134, 49ers -150

In a game likely to be closely contested, the 49ers are 2.5-point favorites on Thursday Night Football against the Rams. The total line is set at 49 points, which is considered high for the over/under.

The NFL Week 15 action between the Rams and 49ers at Levi's Stadium is scheduled for 8:15pm on Thursday. For detailed analysis, see our full Rams vs 49ers prediction.

Ravens vs. Giants Odds

• Spread: Ravens -16.5 (+100), Giants +16.5 (-110)
• Total: Over/Under 42.5 (-110/-110)
• Moneyline: Ravens -1350, Giants +870

A considerable spread means the Giants are 16.5-point underdogs in their clash against the Ravens. The total line is set at 42.5 points.

The game between the Ravens and Giants at MetLife Stadium is scheduled for 1:00pm on Sunday. For Dimers' full betting preview, check out our Ravens vs Giants prediction.

Jets vs. Jaguars Odds

• Spread: Jets -3.5 (-110), Jaguars +3.5 (-115)
• Total: Over/Under 40.5 (-105/-110)
• Moneyline: Jets -166, Jaguars +150

In what is expected to be a close game, the Jaguars are 3.5-point underdogs in their clash against the Jets. The total line is set at 40.5 points.

This week's game between the Jets and Jaguars at EverBank Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Jets vs Jaguars prediction.

Commanders vs. Saints Odds

• Spread: Commanders -7.5 (-105), Saints +7.5 (-110)
• Total: Over/Under 43.5 (-105/-108)
• Moneyline: Commanders -345, Saints +310

By around a touchdown, the Saints face a +7.5 point spread as underdogs in their clash against the Commanders. The total line is set at 43.5 points.

The NFL Week 15 matchup between the Commanders and Saints at Caesars Superdome is scheduled for 1:00pm on Sunday. For Dimers' full betting preview, check out our Commanders vs Saints prediction.

Bengals vs. Titans Odds

• Spread: Bengals -4.5 (-120), Titans +4.5 (-102)
• Total: Over/Under 46.5 (-110/-105)
• Moneyline: Bengals -230, Titans +200

According to the oddsmakers, the Titans are 4.5-point underdogs in their clash against the Bengals. The total line is set at 46.5 points, which is considered high for the over/under.

The clash between the Bengals and Titans at Nissan Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Bengals vs Titans prediction.

Dolphins vs. Texans Odds

• Spread: Dolphins +3 (-112), Texans -3 (-105)
• Total: Over/Under 46.5 (-110/-105)
• Moneyline: Dolphins +130, Texans -148

In what is expected to be a close game, the Texans are 3-point favorites in their clash against the Dolphins. The total line is set at 46.5 points, which is considered high for the over/under.

This week's matchup between the Dolphins and Texans at NRG Stadium begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Dolphins vs Texans prediction.

Chiefs vs. Browns Odds

• Spread: Chiefs -4.5 (-105), Browns +4.5 (-115)
• Total: Over/Under 43.5 (-110/-110)
• Moneyline: Chiefs -215, Browns +185

According to the sportsbooks, the Browns are 4.5-point underdogs in their clash against the Chiefs. The total line is set at 43.5 points.

The NFL Week 15 matchup between the Chiefs and Browns at Huntington Bank Field is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full Chiefs vs Browns prediction.

Cowboys vs. Panthers Odds

• Spread: Cowboys +3 (-112), Panthers -3 (-105)
• Total: Over/Under 42.5 (-120/-102)
• Moneyline: Cowboys +130, Panthers -145

In what appears to be a tight matchup, the Panthers are 3-point favorites in their clash against the Cowboys. The total line is set at 42.5 points.

The game between the Cowboys and Panthers at Bank of America Stadium is scheduled for 1:00pm on Sunday. For Dimers' full betting preview, check out our Cowboys vs Panthers prediction.

Patriots vs. Cardinals Odds

• Spread: Patriots +6.5 (-115), Cardinals -6.5 (-105)
• Total: Over/Under 46.5 (-104/-112)
• Moneyline: Patriots +215, Cardinals -230

By roughly a touchdown, the Cardinals face a -6.5 point spread as favorites in their clash against the Patriots. The total line is set at 46.5 points, which is considered high for the over/under.

This week's game between the Patriots and Cardinals at State Farm Stadium is scheduled for 4:25pm on Sunday. For more detailed analysis, check out our full Patriots vs Cardinals prediction.

Buccaneers vs. Chargers Odds

• Spread: Buccaneers +2.5 (+100), Chargers -2.5 (-120)
• Total: Over/Under 45.5 (-105/-112)
• Moneyline: Buccaneers +132, Chargers -142

In what is expected to be a close game, the Chargers are 2.5-point favorites in their clash against the Buccaneers. The total line is set at 45.5 points, which is considered high for the over/under.

The NFL Week 15 clash between the Buccaneers and Chargers at SoFi Stadium kicks off at 4:25pm on Sunday. For Dimers' full betting preview, check out our Buccaneers vs Chargers prediction.

Bills vs. Lions Odds

• Spread: Bills +2.5 (+100), Lions -2.5 (-110)
• Total: Over/Under 54.5 (-110/-110)
• Moneyline: Bills +124, Lions -142

In a game likely to be closely contested, the Lions are 2.5-point favorites in their clash against the Bills. Witha high-scoring affair anticipated, the total line is set at 54.5 points.

The action between the Bills and Lions at Ford Field is scheduled for 4:25pm on Sunday. For more detailed analysis, check out our full Bills vs Lions prediction.

Colts vs. Broncos Odds

• Spread: Colts +4 (-110), Broncos -4 (-110)
• Total: Over/Under 44 (-108/-110)
• Moneyline: Colts +176, Broncos -198

According to the sportsbooks, the Broncos are 4-point favorites in their clash against the Colts. The total line is set at 44 points.

This week's action between the Colts and Broncos at Empower Field at Mile High is scheduled for 4:25pm on Sunday. For Dimers' full betting preview, check out our Colts vs Broncos prediction.

Steelers vs. Eagles Odds

• Spread: Steelers +5.5 (-110), Eagles -5.5 (-108)
• Total: Over/Under 42.5 (-115/-105)
• Moneyline: Steelers +205, Eagles -225

By roughly a touchdown, the Eagles face a -5.5 point spread as favorites in their clash against the Steelers. The total line is set at 42.5 points.

The NFL Week 15 matchup between the Steelers and Eagles at Lincoln Financial Field begins at 4:25pm on Sunday. For more detailed analysis, check out our full Steelers vs Eagles prediction.

Packers vs. Seahawks Odds

• Spread: Packers -2.5 (-115), Seahawks +2.5 (-105)
• Total: Over/Under 46.5 (-105/-115)
• Moneyline: Packers -135, Seahawks +125

In a game likely to be closely contested, the Seahawks are 2.5-point underdogs in their Sunday Night Football clash against the Packers. The total line is set at 46.5 points, which is considered high for the over/under.

The clash between the Packers and Seahawks at Lumen Field begins at 8:20pm on Sunday. For Dimers' full betting preview, check out our Packers vs Seahawks prediction.

Bears vs. Vikings Odds

• Spread: Bears +7 (-115), Vikings -7 (-102)
• Total: Over/Under 44.5 (-108/-112)
• Moneyline: Bears +260, Vikings -305

By around a touchdown, the Vikings face a -7 point spread as favorites on Monday Night Football against the Steelers. The total line is set at 44.5 points.

This week's matchup between the Bears and Vikings at U.S. Bank Stadium kicks off at 8:00pm on Monday. For more detailed analysis, check out our full Bears vs Vikings prediction.

Falcons vs. Raiders Odds

• Spread: Falcons -4 (-108), Raiders +4 (-112)
• Total: Over/Under 44 (-110/-105)
• Moneyline: Falcons -200, Raiders +180

According to the sportsbooks, the Raiders are 4-point underdogs on Monday Night Football against the Falcons. The total line is set at 44 points.

The NFL Week 15 matchup between the Falcons and Raiders at Allegiant Stadium kicks off at 8:30pm on Monday. For Dimers' full betting preview, check out our Falcons vs Raiders prediction.

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NFL Odds: Week 15

Discover the odds for each NFL Week 15 matchup. Please note that these odds are accurate at the time of publication and may change.

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Conclusion

As Week 15 approaches, these NFL odds ensure you're ready for every game, right up to the matchup between the Falcons and Raiders on Monday Night Football, where the Falcons are favored by 4 points.

For more Week 15 betting coverage, view our NFL picks, NFL prop bets, NFL trends and NFL futures.