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NFL Betting Preview: Analyzing Every Week 5 Matchup

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Written by Nick Slade
Reviewed by Dave Garofolo
We put every effort into ensuring information on Dimers is accurate. But double-check details that matter to you before making any wager.
NFL preview, NFL betting, NFL odds,  NFL spreads
Take a deep dive into the best betting opportunities for NFL Week 5

As we head into Week 5 of the 2024 NFL season, we've analyzed a schedule that features a mix of tightly contested games and heavily favored matchups. Each game carries significant implications as teams seek to establish early control in their respective divisions. Let’s preview some key contests and betting opportunities for the upcoming week.

Thursday Night: Buccaneers vs. Falcons

Week 5 kicks off with a pivotal NFC South matchup between the Tampa Bay Buccaneers and the Atlanta Falcons. Both teams are vying for divisional supremacy, and this game is expected to be a nail-biter. The Falcons hold a slight edge with a 54% win probability. Atlanta’s strong run game will look to overpower a Buccaneers defense that has been reliable but vulnerable at times. Tampa Bay, on the other hand, will lean heavily on its defense to keep the game close. Expect this one to come down to the wire, with turnovers and special teams play potentially making the difference.

Sunday Morning: Jets vs. Vikings in London

The NFL heads overseas for a morning showdown between the Minnesota Vikings and New York Jets. With a 61% chance of winning, the Vikings come into this game as favorites. Their balanced offensive attack, led by quarterback Sam Darnold, should challenge a Jets defense that has been inconsistent so far. For the Jets, their defense will need to play at its best to limit the Vikings’ high-powered offense. A predicted score of 22-19 suggests that this will be a hard-fought contest with the Vikings likely edging it out.

AFC North Rivalry: Ravens vs. Bengals

One of the most intriguing matchups in the early Sunday slate is the AFC North rivalry game between the Baltimore Ravens and Cincinnati Bengals. Baltimore is favored with a 57% win probability, thanks in large part to quarterback Lamar Jackson's dual-threat capabilities and a stout defense. The Bengals, however, will rely on quarterback Joe Burrow to regain his form if they hope to pull off the upset. This one has all the makings of a classic divisional showdown, and with a predicted score of 26-24, it could come down to which team executes better in the fourth quarter.

Commanders vs. Browns: Washington Strong Favorites

The Washington Commanders are expected to dominate the Cleveland Browns, coming in as 64% favorites. Cleveland’s struggles against top-tier defenses could be their undoing here, as Washington’s defense continues to perform at a high level. Offensively, Washington is predicted to find just enough success to secure a 25-21 victory. The Browns will need their ground game to be effective to keep this contest close.

49ers vs. Cardinals: San Francisco's Dominance

The San Francisco 49ers enter Week 5 with the highest win probability of the week at 72% as they take on the Arizona Cardinals. San Francisco’s defense has been nearly impenetrable, and their offense remains one of the most balanced in the league. Arizona has struggled with consistency, making it hard to envision them mounting a significant challenge. A predicted score of 28-21 suggests the Cardinals may keep it close for a while, but San Francisco’s overall dominance should ultimately shine through.

Sunday Night: Steelers vs. Cowboys

In prime time, the Pittsburgh Steelers are slight favorites (57%) against the Dallas Cowboys. The Steelers' ferocious pass rush could cause problems for a Dallas offense that has been up and down all season. However, the Cowboys have shown resilience, and this game is expected to stay close throughout. With a predicted 22-21 Steelers victory, bettors should keep an eye on turnovers and field position as key factors in this matchup.

Monday Night: Chiefs vs. Saints

To close out Week 5, the Kansas City Chiefs face the New Orleans Saints as heavy favorites with a 69% win probability. The Chiefs’ offense, led by Patrick Mahomes, is expected to be too much for the Saints to handle. The Saints’ defense will need to produce a near-flawless performance to keep this game competitive. A predicted 23-19 victory for the Chiefs suggests that while New Orleans may hang around, Kansas City’s offensive firepower should ultimately carry the day.


Top Moneyline Plays for Week 5

Here are five teams that present strong value as moneyline picks based on their expected performance:

San Francisco 49ers

The 49ers are projected to beat the Cardinals 28-21. With their elite defense and efficient offense, they’re one of the safest moneyline bets this week.

Kansas City Chiefs:

Kansas City is favored to win 23-19 over the Saints. The Chiefs’ explosive offense, combined with Mahomes' leadership, makes them a reliable pick.

Baltimore Ravens:

Predicted to narrowly defeat the Bengals 26-24, the Ravens' ability to adapt to different game situations makes them a strong bet in close matchups.

Buffalo Bills:

Despite a close 24-23 predicted victory over the Texans, the Bills’ overall talent and quarterback Josh Allen’s playmaking ability give them the edge.

Seattle Seahawks:

The Seahawks are favored to beat the Giants 24-19. Their balanced approach on both sides of the ball makes them a dependable moneyline option.

Top Spread Plays in Week 5

If you’re betting against the spread, here are some teams that offer solid value:

Las Vegas Raiders:

With a +2.5 spread against the Denver Broncos and a 58.2% chance of covering, the Raiders have a good chance to keep the game close or even pull off a win.

Dallas Cowboys:

The Cowboys are +2.5 underdogs against the Steelers, with a 58.2% probability of covering the spread. Their resilience in close games makes this a promising pick.

Carolina Panthers:

Despite being +4.0 underdogs against the Bears, the Panthers have a 56.5% chance of covering, indicating a closer game than many expect.

Best Over/Under Plays for Week 5

When it comes to the over/under, a couple of games stand out:

Browns vs. Commanders:

With an over/under line of 43.5 and a 58.2% probability favoring the over, this matchup could see more scoring than anticipated.

Jets vs. Vikings:

The over/under for this game is set at 40.5, with a 54.9% chance of hitting the over, offering good value for bettors.

As always, make sure to balance the data with the odds to maximize your returns. Week 5 promises to deliver thrilling matchups and plenty of betting opportunities.


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To make sure you get accurate and helpful information, this guide has been edited by Dave Garofolo as part of our fact-checking process.
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Written by
Nick Slade
Chief Content Officer

Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers and Stats Insider, and specializes in soccer, NBA and NHL betting.

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