NFL Best Bets: Week 16 Picks Include Jaguars vs. Raiders Play [12/22/2024]

NFL betting is back for another enticing day on 12/22, and we're here to give you our top picks for Sunday's football action.

Today's NFL best bets come from a range of matchups, including Jaguars vs. Raiders and 49ers vs. Dolphins, with this article updated throughout the day to highlight the most attractive upcoming games.

Featuring a standout moneyline play at 4:25PM ET, these picks are based on cutting-edge simulations and machine learning.

For unlimited access to everything Dimers has to offer on Sunday, December 22, 2024—including our full set of NFL picks and best bets—check out Dimers Pro.

LIMITED TIME: Get 50% Off Pro with Code HOLIDAYS

Get Dimers Pro

Sign up with code HOLIDAYS at checkout now to get 50% off your first month of Dimers Pro! Don’t miss out—this offer won’t last forever.

List of NFL Best Bets Today [12/22, Updated: 4:00PM ET]

After digging deep into the numbers and conducting thousands of simulations, our famous predictive analytics model has figured out the best football bets for Sunday, December 22, 2024.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro users.

Raiders ML (-130)

• Edge: 2.9%
• Probability: 59.4%
• Matchup: Jaguars vs. Raiders (4:25PM ET, Sunday)

Our model has pinpointed the next NFL betting opportunity today, which comes in the Jaguars vs. Raiders game. We recommend a bet on Raiders ML at -130 odds, offering an edge of 2.9%.

Raiders ML vs. Jaguars

-130

Bet $25
Payout $44.22Bet $25, Payout $44.22

49ers vs. Dolphins Under 44.5 Points (-110)

• Edge: 2.2%
• Probability: 54.6%
• Matchup: 49ers vs. Dolphins (4:25PM ET, Sunday)

Our model has found another great NFL bet for Sunday's sports action, this time in the matchup between the 49ers and Dolphins. We suggest placing an over/under wager on Under 44.5 Points at -110 odds, with our analysis showing a compelling 2.2% edge.

49ers vs. Dolphins Under 44.5 Points

-110

Bet $25
Payout $47.73Bet $25, Payout $47.73

MORE: NFL Props

Cowboys +4 (-110)

• Edge: 6.5%
• Probability: 58.9%
• Matchup: Buccaneers vs. Cowboys (8:20PM ET, Sunday)

Our next pick for today's football action is from the Buccaneers vs. Cowboys game. We recommend a spread bet on Cowboys +4 at -110 odds. Our model suggests a favorable 6.5% edge for this wager.

Cowboys +4 vs. Buccaneers

-110

Bet $25
Payout $47.73Bet $25, Payout $47.73

MORE: Sunday's NFL Trends

NFL Best Bets: Sunday, 12/22/2024

As of 4:00PM ET, here are the next three NFL bets recommended by our model:

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.

While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you unlimited access to today's best bets across all sports, powered by our advanced model.

Among Sunday's NFL picks is a +176 moneyline play with an edge of 2.0%.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for December 22, 2024.

List of Upcoming NFL Games to Bet On [12/22/2024]

• Vikings vs. Seahawks (4:05PM ET, Sunday)
• Patriots vs. Bills (4:25PM ET, Sunday)
• Jaguars vs. Raiders (4:25PM ET, Sunday)
• 49ers vs. Dolphins (4:25PM ET, Sunday)
• Buccaneers vs. Cowboys (8:20PM ET, Sunday)

See How Dimers Pro Enhances Your Best Bets

Unlock the full power of our best bets with Dimers Pro. Watch this explainer video to see how it can elevate your betting game.

NFL Fantasy and Betting Promos

Make the most of Dimers' full range of predictions for this week's NFL matchups by considering the two offers listed below.

DraftKings Pick6

Sign up for DraftKings Pick6 today! Play $5 to get $50 in Pick6 Credits immediately.

FanDuel Sportsbook

Looking to place a wager on this week's NFL best bets? Sign up to FanDuel Sportsbook now! Bet $5 to get $300 in bonus bets if your bet wins.

More on NFL

This article is part of our NFL player props and NFL best bets series.

For more NFL betting content, we have NFL trends for every game, as well as daily NFL betting news and the latest Super Bowl odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate NFL insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.