Yankees vs. Pirates Prediction: Yankees Predicted to Win Sunday's MLB Matchup [4/6/2025]

The Pittsburgh Pirates will square off with the New York Yankees in MLB action at PNC Park on Sunday, starting at 1:35PM ET.

Andrew Heaney (0-0, 1.80 ERA) will be the starting pitcher for the Pirates, while the Yankees have opted for Will Warren (0-0, 3.60 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Yankees as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's NY Yankees-Pittsburgh game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Yankees with a win probability of 59%, while the Pirates have 41%."

For expanded analysis of Sunday's matchup, including best bets and picks, visit our interactive Yankees vs. Pirates predictions page.

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Yankees vs. Yankees Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB game between the Yankees and Pirates 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Yankees a 59% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 54% chance of covering the run line, while the 8.5-run over/under has a 51% chance of going over.

Pre-Game Probabilities

Last Updated: 5:28PM, Apr 6

Moneyline

Over / Under

Run Line

Yankees

Win %

59%

41%

-165

+150

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Pirates

Yankees NYY

-165

Win %

59%

41%

See Matchup

Pirates PIT

+150

Will Warren 0-0, 3.60 ERA

Andrew Heaney 0-0, 1.80 ERA

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Yankees vs. Pirates Odds [4/6/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Yankees vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Yankees vs. Pirates matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Yankees vs. Pirates Game-Day Updates and Essential Details

Sunday's MLB action between the Pirates and Yankees at PNC Park is scheduled to commence at 1:35PM ET.

• Who: New York Yankees vs. Pittsburgh Pirates
• Date: Sunday, April 6, 2025
• Time: 1:35PM ET/10:35AM PT
• Venue: PNC Park

Dimers.com's in-depth preview of Sunday's Yankees vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any NY Yankees vs. Pittsburgh picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Yankees, with a 59% win probability, will likely beat the Pirates on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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