Yankees vs. Orioles Prediction: Yankees Predicted to Win Monday's MLB Matchup [4/28/2025]

The Baltimore Orioles will face the New York Yankees, in what is expected to be a tight MLB game, at Oriole Park at Camden Yards on Monday, starting at 6:35PM ET.

Tomoyuki Sugano (2-1, 3.54 ERA) will be the starting pitcher for the Orioles, while the Yankees have opted for Will Warren (1-0, 4.79 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Yankees as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's NY Yankees-Baltimore game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Yankees are likely to win, with a probability of 53%, compared to the Orioles' 47%."

For further insights into Monday's matchup, including best bets and picks, visit our interactive Yankees vs. Orioles predictions page.

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Orioles vs. Yankees Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the result of Monday's MLB game between the Yankees and Orioles 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Yankees a 53% chance of beating the Orioles.

According to our model, the Orioles (+1.5) have a 59% chance of covering the run line, while the over/under total of 9.5 runs has a 51% chance of staying under.

Pre-Game Probabilities

Last Updated: 10:28PM, Apr 28

Moneyline

Over / Under

Run Line

Yankees

Win %

53%

47%

-130

+116

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Orioles

Yankees NYY

-130

Win %

53%

47%

See Matchup

Orioles BAL

+116

Will Warren 1-0, 4.79 ERA

Tomoyuki Sugano 2-1, 3.54 ERA

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Yankees vs. Orioles Odds [4/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Yankees vs. Orioles Picks and Best Bets

Our model's strongest edge in today's Yankees vs. Orioles matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Yankees vs. Orioles Game-Day Updates and Essential Details

Monday's MLB game between the Orioles and Yankees at Oriole Park at Camden Yards is scheduled to commence at 6:35PM ET.

• Who: New York Yankees vs. Baltimore Orioles
• Date: Monday, April 28, 2025
• Time: 6:35PM ET/3:35PM PT
• Venue: Oriole Park at Camden Yards

Dimers.com's in-depth preview of Monday's Yankees vs. Orioles matchup includes our prediction, picks and the latest betting odds.

Before making any NY Yankees vs. Baltimore picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Yankees, with a 53% win probability, will likely beat the Orioles on Monday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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