Mets vs. Nationals Prediction: Mets Predicted to Win Friday's MLB Matchup [4/25/2025]

The Washington Nationals will square off with the New York Mets in MLB action at Nationals Park on Friday, beginning at 6:45PM ET.

The Nationals will start Jake Irvin (2-0, 3.68 ERA), while the Mets are going with Kodai Senga (3-1, 0.79 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Mets as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's NY Mets-Washington game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Mets' chance of winning is 60%, while the Nationals' is 40%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Mets vs. Nationals predictions page.

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Nationals vs. Mets Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the result of Friday's MLB matchup between the Mets and Nationals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Mets a 60% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 53% chance of covering the run line, while the 9-run over/under has a 53% chance of staying under.

Pre-Game Probabilities

Last Updated: 10:28PM, Apr 25

Moneyline

Over / Under

Run Line

Mets

Win %

60%

40%

-185

+165

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See Matchup

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Nationals

Mets NYM

-185

Win %

60%

40%

See Matchup

Nationals WSH

+165

Kodai Senga 3-1, 0.79 ERA

Jake Irvin 2-0, 3.68 ERA

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Mets vs. Nationals Odds [4/25/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Mets vs. Nationals Picks and Best Bets

Our model's biggest edge in today's Mets vs. Nationals matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

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Mets vs. Nationals Game-Day Updates and Essential Details

Friday's MLB action between the Nationals and Mets at Nationals Park is scheduled to begin at 6:45PM ET.

• Who: New York Mets vs. Washington Nationals
• Date: Friday, April 25, 2025
• Time: 6:45PM ET/3:45PM PT
• Venue: Nationals Park

Dimers.com's in-depth preview of Friday's Mets vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any NY Mets vs. Washington picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Mets, with a 60% win probability, will likely beat the Nationals on Friday.

AI and automation have enhanced this article to quickly deliver accurate Mets vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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