Knicks vs. Spurs Prediction: New York Predicted to Win Wednesday's NBA Game [3/19/2025]

The San Antonio Spurs will square off with the favored New York Knicks in NBA action at Frost Bank Center on Wednesday, commencing at 8:00PM ET.

Based on updated simulations and today’s injury news, Dimers' proven NBA model (see Dimers Pro for full access) predicts the Knicks as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's New York-San Antonio game 10,000 times," said Damien Souness from Dimers.

"With the latest updates and numerous other variables, we estimate the Knicks' chance of winning at 73%, with the Spurs at 27%."

This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like Stephon Castle, Devin Vassell and Keldon Johnson, while the Knicks will look to Karl-Anthony Towns, Mikal Bridges and OG Anunoby.

For expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Knicks vs. Spurs predictions page.

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Knicks vs. Knicks Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's NBA matchup between the Knicks and Spurs 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the Knicks a 73% chance of defeating the Spurs. Our predicted final score has the Knicks winning 117-110.

According to our model, the Spurs (+8) have a 55% chance of covering the spread, while the over/under total of 227.5 points has a 51% chance of going over.

Knicks vs. Spurs Odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Boost your NBA betting by exploring the latest NBA betting promos, sourced from top sportsbooks and DFS operators.

Knicks vs. Spurs Picks and Best Bets

Our model's biggest edge in today's Knicks vs. Spurs matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best NBA picks and NBA best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Knicks vs. Spurs Player Props

NBA player props are an enjoyable way to wager on Wednesday's Knicks vs. Spurs matchup without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Frost Bank Center.

Karl-Anthony Towns is expected to lead the Knicks with 26 points, 13 rebounds and 3 assists, while Stephon Castle is projected to have 20 points, 4 rebounds and 4 assists for the Spurs.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Projected Box Scores for Every NBA Game

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Knicks vs. Spurs Game-Day Updates and Essential Details

Wednesday's game between the Spurs and Knicks at Frost Bank Center is scheduled to begin at 8:00PM ET.

• Who: New York Knicks vs. San Antonio Spurs
• Date: Wednesday, March 19, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: Frost Bank Center

Dimers.com's in-depth preview of Wednesday's Knicks vs. Spurs matchup includes our prediction, picks and the latest betting odds.

Before making any New York vs. San Antonio picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

Conclusion

We predict the Knicks, with a 73% win probability, will likely beat the Spurs on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Knicks vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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