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Patriots vs. 49ers Prediction: San Francisco Predicted to Win Following Latest Data Analysis for NFL Week 4 [2024]
The San Francisco 49ers and New England Patriots will meet in Week 4 of the NFL season at Levi's Stadium on Sunday, starting at 4:05PM ET.
Based on updated simulation results, Dimers' proven NFL model (see Dimers Pro for full access) projects the 49ers as the most likely winner of today's game.
"Using the most recent data, our experts ran 10,000 simulations of Sunday's Patriots-49ers game," said Dimers' Chief Content Officer, Nick Slade.
"After accounting for recent updates and other variables, our prediction shows the 49ers with a win probability of 83%, while the Patriots have 17%."
Patriots vs. 49ers Game-Day Updates and Essential Details
The NFL Week 4 action between the 49ers and Patriots at Levi's Stadium is scheduled to start at 4:05PM ET.
- Who: New England Patriots vs. San Francisco 49ers
- Date: Sunday, September 29, 2024
- Time: 4:05PM ET/1:05PM PT
- Venue: Levi's Stadium
- Tickets: Get tickets for the game on Ticketmaster
- Merchandise: Buy 49ers and Patriots gear at Fanatics
- Live Stream: Watch this game on FOX via Hulu or FuboTV
Dimers.com's comprehensive preview of this week's Patriots vs. 49ers matchup includes our prediction, picks and the latest betting odds.
Before making any 49ers vs. Patriots picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.
READER EXCLUSIVE: Sign up with code 20FOOTBALL at checkout right now to receive 20% off your first month of Dimers Pro! This offer won't last forever.
Patriots vs. 49ers Predictions
Using trusted machine learning and statistical analysis, we have simulated the result of Sunday's NFL matchup between the Patriots and 49ers 10,000 times as part of our NFL predictions coverage.
Our independent predictive model currently gives the 49ers an 83% chance of beating the Patriots in Week 4 of the NFL season. Our predicted final score has the 49ers winning 25-15.
According to our model, the Patriots (+10.5) have a 54% chance of covering the spread, while the 42.5-point over/under has a 54% chance of staying under.
Along with our Patriots vs. 49ers predictions, we've also here's what else we've got for today’s action:
Patriots vs. 49ers Odds
We have researched the best betting odds in America for this game, which are listed here:
| Bet Type | Patriots | 49ers |
|---|---|---|
| Spread | +10.5 (-110) | -10.5 (-108) |
| Moneyline | +450 | -575 |
| Total | o42.5 (-105) | u42.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Patriots vs. 49ers Picks
Our model's strongest edge in today's Patriots vs. 49ers matchup is on the spread.
Our expert predictions, matched against the latest odds, reveal the best NFL picks for every game throughout the season.
Full access to our picks, including this one, is available via Dimers Pro.
Patriots vs. 49ers TD Scorers
Who will score the first touchdown in Patriots vs. 49ers?
According to our model, San Francisco's Jordan Mason is most likely to score the first touchdown in Patriots vs. 49ers.
Our projections give Mason a 14.4% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 53.6% chance of scoring an anytime touchdown.
First Touchdown Scorer Predictions
New England Patriots
| Player | First TD Probability |
|---|---|
| Rhamondre Stevenson | 9.9% |
| Antonio Gibson | 5.0% |
| Hunter Henry | 4.6% |
San Francisco 49ers
| Player | First TD Probability |
|---|---|
| Jordan Mason | 14.4% |
| Deebo Samuel | 10.2% |
| Brandon Aiyuk | 9.2% |
Anytime Touchdown Scorer Predictions
New England Patriots
| Player | Anytime TD Probability |
|---|---|
| Rhamondre Stevenson | 40.4% |
| Antonio Gibson | 22.6% |
| Hunter Henry | 20.9% |
San Francisco 49ers
| Player | Anytime TD Probability |
|---|---|
| Jordan Mason | 53.6% |
| Deebo Samuel | 40.9% |
| Brandon Aiyuk | 38.4% |
For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 4 touchdown scorer predictions
Patriots vs 49ers Player Props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Patriots and 49ers. For detailed projections, join Dimers Pro.
Already a Dimers Pro member? Head to our Patriots-49ers page now to access every player prop projection.
Patriots vs. 49ers Quarterbacks
Of the starting quarterbacks, the Patriots' Jacoby Brissett is projected to throw for fewer yards than the 49ers' Brock Purdy.
Patriots Rushing
Rhamondre Stevenson, Antonio Gibson and Jacoby Brissett are projected to be the leading rushers for the Patriots.
| Player | Position |
|---|---|
| Rhamondre Stevenson | RB |
| Antonio Gibson | RB |
| Jacoby Brissett | QB |
49ers Rushing
Jordan Mason, Isaac Guerendo and Deebo Samuel are expected to lead the 49ers in rushing yards.
| Player | Position |
|---|---|
| Jordan Mason | RB |
| Isaac Guerendo | RB |
| Deebo Samuel | WR |
Patriots Receiving
DeMario Douglas, Hunter Henry, Ja'Lynn Polk, K.J. Osborn and Rhamondre Stevenson are projected to top the receiving yards for the Patriots.
| Player | Position |
|---|---|
| DeMario Douglas | WR |
| Hunter Henry | TE |
| Ja'Lynn Polk | WR |
| K.J. Osborn | WR |
| Rhamondre Stevenson | RB |
49ers Receiving
Brandon Aiyuk, Deebo Samuel, George Kittle, Jauan Jennings and Jordan Mason are projected to lead the 49ers in receiving yards.
| Player | Position |
|---|---|
| Brandon Aiyuk | WR |
| Deebo Samuel | WR |
| George Kittle | TE |
| Jauan Jennings | WR |
| Jordan Mason | RB |
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Conclusion
We predict the 49ers, with an 83% win probability, will likely beat the Patriots in Week 4 of the NFL season.
AI and automation have enhanced this article to quickly deliver accurate Patriots vs. 49ers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on NFL
Keep up with the latest NFL betting news and our data-driven NFL best bets and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the most up-to-date projections for the Super Bowl, AFC, NFC and each division.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS and NFL, delivers game previews, best bets and props. He has contributed insightful articles at Dimers since 2020 as Head of Social and Community.
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