NBA Picks Today: Monday's Best Bets Include Clippers vs. Nuggets Play [4/21/2025]

NBA betting is back for another pulse-pounding slate on 4/21, and we're here to give you our top basketball picks for Monday's action.

Today's NBA best bets come from a range of matchups, including the Clippers vs. Nuggets game at 10:00PM ET, with this article updated throughout the day to highlight the most attractive upcoming games.

Featuring a standout moneyline play with an edge of 4.1%, these picks are based on cutting-edge simulations and machine learning.

For unlimited access to everything Dimers has to offer on Monday, April 21, 2025—including our full set of NBA picks and best bets—check out Dimers Pro.

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List of NBA Picks Tonight [4/21, Updated: 9:32PM ET]

After diving deep into the numbers and running thousands of simulations, our famous predictive analytics model has figured out the best basketball bets for Monday, April 21, 2025.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro subscribers.

Clippers ML (-105)

• Edge: 4.1%
• Probability: 55.3%
• Matchup: Clippers vs. Nuggets (10:00PM ET, Monday)

Drawing from our Clippers vs Nuggets prediction, our model has pinpointed the next NBA betting opportunity tonight, which comes in the Clippers vs. Nuggets matchup. We recommend a bet on the Clippers ML at -105 odds, offering an edge of 4.1%.

Clippers ML vs. Nuggets

-105

Bet $25
Payout $48.80Bet $25, Payout $48.80

Nuggets -1.5 (+100)

• Edge: 2.7%
• Probability: 52.7%
• Matchup: Clippers vs. Nuggets (10:00PM ET, Monday)

Our model has found another great NBA bet for Monday's basketball action, again in the matchup between the Clippers and Nuggets. We suggest placing a spread wager on Nuggets -1.5 at +100 odds, with our analysis showing a compelling 2.7% edge.

Nuggets -1.5 vs. Clippers

+100

Bet $25
Payout $50Bet $25, Payout $50

MORE: NBA Props Monday

NBA Best Bets: Monday, 4/21/2025

As of 9:32PM ET, here are the next two NBA bets recommended by our model:

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you unlimited access to today's best bets across all sports, powered by our advanced model.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for April 21, 2025.

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More NBA Betting Guides

This article is part of our NBA player props and NBA best bets series. For related content on April 21, check out:

• Monday's NBA First Basket Predictions
• NBA Player Prop Picks for Monday

List of Upcoming NBA Games to Bet On [4/21/2025]

• Clippers vs. Nuggets (10:00PM ET, Monday)
• Bucks vs. Pacers (7:00PM ET, Tuesday)
• Grizzlies vs. Thunder (7:30PM ET, Tuesday)

More About NBA

For more NBA betting content, we have NBA trends for every game, as well as daily NBA betting news and the latest NBA title odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate NBA insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.