Nationals vs. Twins Prediction and Odds - Apr 21, 2023

The Minnesota Twins and Washington Nationals meet in MLB action at Target Field on Friday, starting at 8:10PM ET.

The Twins will have Tyler Mahle (1-2, 4.11 ERA) start, up against Trevor Williams (1-1, 3.52 ERA) for the Nationals.

Dimers' top betting picks for Nationals vs. Twins, plus game predictions and betting odds, are detailed below.

Who will win Nationals vs. Twins?

Based on cutting-edge machine learning and data, Dimers.com has simulated Friday's Nationals-Twins MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Twins a 65% chance of winning against the Nationals.

More: Nationals vs. Twins Simulated 10K Times

Nationals vs. Twins Game Odds

• Run Line: Twins -1.5 (-105), Nationals +1.5 (+100)
• Moneyline: Twins -225, Nationals +205
• Total: Over/Under 7.5 (-110/-105)

Run Line, Moneyline and Over/Under

The Twins are listed as -1.5 favorites versus the Nationals, with -105 at BetMGM the best odds currently available.

For the underdog Nationals (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +100.

BetMGM currently has the best moneyline odds for the Twins at -225, which means you can risk $225 to win $100, for a total payout of $325, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Nationals at +205, where you can bet $100 to profit $205, earning a total payout of $305, if they win.

The Over/Under is set at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Nationals (+1.5) are a 53% chance of covering the run line, while the Over/Under total of 7.5 runs is a 54% chance of going Over.

More: Track Your Bets via Dimers' Bet Center

Best Bets for Nationals vs. Twins

• Run Line: Nationals +1.5 @ +100 via DraftKings Sportsbook (53% probability)
• Moneyline: Nationals @ +205 via DraftKings Sportsbook (2.1% edge)
• Total: Over 7.5 @ -110 via DraftKings Sportsbook (54% probability)

Our best bets are based on complex modeling and betting intelligence to help you make smarter decisions with your state's legal sportsbooks.

While the Twins are more likely to win the game, according to DimersBOT, taking the Nationals moneyline is the best option due to the 2.1% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen on Dimers is one of the keys to achieving long-term profitability.

Nationals vs. Twins Prediction

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Dimers has full coverage of Friday's Nationals-Twins matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep an eye on this page for the latest betting insights before Nationals vs. Twins on Friday April 21, 2023.

Nationals vs. Twins 2023 Game Info

Friday's matchup between the Twins and Nationals at Target Field is scheduled to begin at 8:10PM ET.

• Who: Washington Nationals vs. Minnesota Twins
• Date: Friday April 21, 2023
• Time: 8:10PM ET / 5:10PM PT
• Venue: Target Field

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Calling Our Shot ⚾️ Best Bets

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

What other MLB games are on today?

Now you've got the 411 on Nationals vs. Twins, check out the latest betting coverage for all upcoming MLB games thanks to Dimers' MLB picks and predictions page, where you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good!

As well as MLB game picks and predicitons, Dimers also provides the best MLB prop bets for today, with our projections for home runs, RBIs, and more lined up against the sportsbook odds every single day of the MLB season.

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the World Series, with our data-led probabilities paired with the best odds on the market.