MLS Betting Tips: Saturday's Picks Include Salt Lake vs. San Jose Play [2/22/2025]

MLS betting is back for another enticing day on 2/22, and we're here to share our top picks for Saturday's soccer action.

Today's MLS best bets come from a range of matchups, including Salt Lake vs. San Jose and Charlotte vs. Seattle, with this article updated throughout the day to highlight the most attractive upcoming games.

Featuring a standout moneyline play at 10:30PM ET, these picks are powered by data-driven simulations and machine learning.

For unlimited access to everything Dimers has to offer on Saturday, February 22, 2025—including our full suite of MLS picks and best bets—check out Dimers Pro.

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List of MLS Betting Tips Tonight [2/22, Updated: 10:02PM ET]

After crunching the numbers and running thousands of simulations, our independent predictive analytics model has identified the best soccer bets for Saturday, February 22, 2025.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro users.

Salt Lake ML (+230)

• Edge: 7.9%
• Probability: 38.2%
• Matchup: Salt Lake vs. San Jose (10:30PM ET, Saturday)

Our model has pinpointed the next MLS betting opportunity tonight, which comes in the Salt Lake vs. San Jose game. We recommend a bet on Salt Lake ML at +230 odds, offering an edge of 7.9%.

Salt Lake ML vs. San Jose

+230

Bet $25
Payout $82.50Bet $25, Payout $82.50

Charlotte vs. Seattle Under 2.5 Goals (-116)

• Edge: 2.8%
• Probability: 56.5%
• Matchup: Charlotte vs. Seattle (10:30PM ET, Saturday)

Our model has found another great MLS bet for Saturday's soccer action, this time in the matchup between Charlotte and Seattle. We suggest placing an over/under wager on Under 2.5 Goals at -116 odds, with our analysis showing a compelling 2.8% edge.

Charlotte vs. Seattle Under 2.5 Goals

-116

Bet $25
Payout $46.55Bet $25, Payout $46.55

MORE: Saturday's Player Prop Picks

MLS Best Bets: Saturday, 2/22/2025

As of 10:02PM ET, here are the next two MLS bets recommended by our model:

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you unlimited access to today's best bets across all sports, powered by our advanced model.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for February 22, 2025.

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List of Upcoming MLS Games to Bet On [2/22/2025]

• Salt Lake vs. San Jose (10:30PM ET, Saturday)
• Charlotte vs. Seattle (10:30PM ET, Saturday)
• Vancouver vs. Portland (4:00PM ET, Sunday)
• San Diego FC vs. LA Galaxy (7:00PM ET, Sunday)

More About MLS

This article is part of our MLS best bets series.

For more MLS betting content, we have MLS betting news and the latest MLS Cup odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate MLS insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.