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Brewers vs. Cardinals Prediction: St. Louis Predicted to Win Friday's MLB Matchup [4/25/2025]
Our expert prediction for Friday's Milwaukee Brewers vs St. Louis Cardinals matchup.

The St. Louis Cardinals and Milwaukee Brewers will lock horns in MLB action at Busch Stadium on Friday, starting at 8:15PM ET.
The Cardinals will start Matthew Liberatore (1-2, 3.60 ERA), while the Brewers have opted for Chad Patrick (1-1, 2.11 ERA).
Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.
"Employing the latest data, our experts simulated Friday's Milwaukee-St. Louis game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"After computing the latest updates and thousands of other inputs, we predict the Cardinals' chance of winning is 56%, while the Brewers' is 44%."
For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Brewers vs. Cardinals predictions page.
Cardinals vs. Brewers Prediction: Who Will Win, Cover the Run Line?
Using innovative machine learning and data, we have simulated the result of Friday's MLB matchup between the Brewers and Cardinals 10,000 times as part of our MLB predictions coverage.
Our leading predictive model currently gives the Cardinals a 56% chance of beating the Brewers.
According to our model, the Brewers (+1.5) have a 63% chance of covering the run line, while the 8-run over/under has a 51% chance of staying under.
Brewers vs. Cardinals Odds [4/25/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
Bet Type | Brewers | Cardinals |
---|---|---|
Run Line | +1.5 (-188) | -1.5 (+160) |
Moneyline | +115 | -130 |
Total | o8 (-104) | u8 (-105) |
All odds are correct at the time of publication and are subject to change.
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Brewers vs. Cardinals Picks and Best Bets
Our model's biggest edge in today's Brewers vs. Cardinals matchup is on the run line.
Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets Today
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Brewers vs. Cardinals Game-Day Updates and Essential Details
Friday's MLB game between the Cardinals and Brewers at Busch Stadium is scheduled to start at 8:15PM ET.
- Who: Milwaukee Brewers vs. St. Louis Cardinals
- Date: Friday, April 25, 2025
- Time: 8:15PM ET/5:15PM PT
- Venue: Busch Stadium
Dimers.com's in-depth preview of Friday's Brewers vs. Cardinals matchup includes our prediction, picks and the latest betting odds.
Before making any Milwaukee vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Cardinals, with a 56% win probability, will likely beat the Brewers on Friday.
AI and automation have enhanced this article to quickly deliver accurate Brewers vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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